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At the heart of medicine lies the physician-patient dialogue, where skillful history-taking paves the way for accurate diagnosis, effective management, and enduring trust. Artificial Intelligence (AI) systems capable of diagnostic dialogue…

Large Language Models (LLMs) have demonstrated great potential for conducting diagnostic conversations but evaluation has been largely limited to language-only interactions, deviating from the real-world requirements of remote care…

While large language models (LLMs) have shown promise in diagnostic dialogue, their capabilities for effective management reasoning - including disease progression, therapeutic response, and safe medication prescription - remain…

Vision impairment and blindness are a major global health challenge where gaps in the ophthalmology workforce limit access to specialist care. We evaluate AMIE, a medically fine-tuned conversational system based on Gemini with integrated…

The shortage of doctors is creating a critical squeeze in access to medical expertise. While conversational Artificial Intelligence (AI) holds promise in addressing this problem, its safe deployment in patient-facing roles remains largely…

Artificial Intelligence · Computer Science 2025-04-11 Antoine Lizée , Pierre-Auguste Beaucoté , James Whitbeck , Marion Doumeingts , Anaël Beaugnon , Isabelle Feldhaus

Large language models (LLMs) have shown remarkable progress in encoding clinical knowledge and responding to complex medical queries with appropriate clinical reasoning. However, their applicability in subspecialist or complex medical…

The scarcity of subspecialist medical expertise, particularly in rare, complex and life-threatening diseases, poses a significant challenge for healthcare delivery. This issue is particularly acute in cardiology where timely, accurate…

Clinician skepticism toward opaque AI hinders adoption in high-stakes healthcare. We present AICare, an interactive and interpretable AI copilot for collaborative clinical decision-making. By analyzing longitudinal electronic health…

Human-Computer Interaction · Computer Science 2026-02-03 Yinghao Zhu , Dehao Sui , Zixiang Wang , Xuning Hu , Lei Gu , Yifan Qi , Tianchen Wu , Ling Wang , Yuan Wei , Wen Tang , Zhihan Cui , Yasha Wang , Lequan Yu , Ewen M Harrison , Junyi Gao , Liantao Ma

With the rapid adoption of large language models (LLMs), conversational AI agents have become widely deployed across real-world applications. To enhance safety, these agents are often equipped with guardrails that moderate harmful content.…

Cryptography and Security · Computer Science 2026-04-14 Ziqing Yang , Yixin Wu , Rui Wen , Michael Backes , Yang Zhang

Artificial intelligence holds great promise for expanding access to expert medical knowledge and reasoning. However, most evaluations of language models rely on static vignettes and multiple-choice questions that fail to reflect the…

Screening patients for clinical trial eligibility remains a manual, time-consuming, and resource-intensive process. We present a secure, scalable proof-of-concept system for Artificial Intelligence (AI)-augmented patient-trial matching that…

Healthcare AI systems have historically faced challenges in merging contextual reasoning, long-term state management, and human-verifiable workflows into a cohesive framework. This paper introduces a completely innovative architecture and…

Artificial Intelligence · Computer Science 2025-12-08 Zag ElSayed , Craig Erickson , Ernest Pedapati

The integration of AI into radiology introduces opportunities for improved clinical care provision and efficiency but it demands a meticulous approach to mitigate potential risks as with any other new technology. Beginning with rigorous…

As artificial intelligence (AI) systems approach and surpass expert human performance across a broad range of tasks, obtaining high-quality human supervision for evaluation and training becomes increasingly challenging. Our focus is on…

Machine Learning · Computer Science 2026-02-25 Ren Yin , Takashi Ishida , Masashi Sugiyama

Messaging patients is a critical part of healthcare communication, helping to improve things like medication adherence and healthy behaviors. However, traditional mobile message design has significant limitations due to its inability to…

Artificial Intelligence · Computer Science 2025-10-01 Junjie Luo , Yihong Guo , Anqi Liu , Ritu Agarwal , Gordon Gao

Engineering workflows such as design optimization, simulation-based diagnosis, control tuning, and model-based systems engineering (MBSE) are iterative, constraint-driven, and shaped by prior decisions. Yet many AI methods still treat these…

Artificial Intelligence · Computer Science 2026-04-10 Tong Duy Son , Zhihao Liu , Piero Brigida , Yerlan Akhmetov , Gurudevan Devarajan , Kai Liu , Ajinkya Bhave

Automated approaches to answer patient-posed health questions are rising, but selecting among systems requires reliable evaluation. The current gold standard for evaluating the free-text artificial intelligence (AI) responses--human expert…

Artificial Intelligence · Computer Science 2026-05-11 Sarvesh Soni , Dina Demner-Fushman

Background: Globally we face a projected shortage of 11 million healthcare practitioners by 2030, and administrative burden consumes 50% of clinical time. Artificial intelligence (AI) has the potential to help alleviate these problems.…

Human-Computer Interaction · Computer Science 2025-08-01 Hashim Hayat , Maksim Kudrautsau , Evgeniy Makarov , Vlad Melnichenko , Tim Tsykunou , Piotr Varaksin , Matt Pavelle , Adam Z. Oskowitz
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