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RNA design aims to identify RNA sequences that fold into a target secondary structure. This task is challenging in terms of computational efficiency. Most existing methods focus on either minimum free energy (MFE)-based or ensemble-based…

Biomolecules · Quantitative Biology 2026-03-04 Tianshuo Zhou , David H. Mathews , Liang Huang

Retrieval-Augmented Generation systems depend on retrieving semantically relevant document chunks to support accurate, grounded outputs from large language models. In structured and repetitive corpora such as regulatory filings, chunk…

Information Retrieval · Computer Science 2026-01-21 Raquib Bin Yousuf , Shengzhe Xu , Mandar Sharma , Andrew Neeser , Chris Latimer , Naren Ramakrishnan

Neural architecture search has been shown to hold great promise towards the automation of deep learning. However in spite of its potential, neural architecture search remains quite costly. To this point, we propose a novel gradient-based…

Machine Learning · Computer Science 2019-02-18 Efi Kokiopoulou , Anja Hauth , Luciano Sbaiz , Andrea Gesmundo , Gabor Bartok , Jesse Berent

Pre-trained multimodal models have achieved significant success in retrieval-based question answering. However, current multimodal retrieval question-answering models face two main challenges. Firstly, utilizing compressed evidence features…

Artificial Intelligence · Computer Science 2023-10-17 Shuwen Yang , Anran Wu , Xingjiao Wu , Luwei Xiao , Tianlong Ma , Cheng Jin , Liang He

Vector data is prevalent across business and scientific applications, and its popularity is growing with the proliferation of learned embeddings. Vector data collections often reach billions of vectors with thousands of dimensions, thus,…

Information Retrieval · Computer Science 2025-09-08 Ilias Azizi , Karima Echihabi , Themis Palpanas

Machine learning tasks are generally formulated as optimization problems, where one searches for an optimal function within a certain functional space. In practice, parameterized functional spaces are considered, in order to be able to…

Artificial Intelligence · Computer Science 2024-12-13 Manon Verbockhaven , Sylvain Chevallier , Guillaume Charpiat , Théo Rudkiewicz

High-level automation is increasingly critical in AI, driven by rapid advances in large language models (LLMs) and AI agents. However, LLMs, despite their general reasoning power, struggle significantly in specialized, data-sensitive tasks…

Machine Learning · Computer Science 2026-02-12 Jialiang Wang , Hanmo Liu , Shimin Di , Zhili Wang , Jiachuan Wang , Lei Chen , Xiaofang Zhou

Searching techniques in most of existing neural architecture search (NAS) algorithms are mainly dominated by differentiable methods for the efficiency reason. In contrast, we develop an efficient continuous evolutionary approach for…

Computer Vision and Pattern Recognition · Computer Science 2020-03-10 Zhaohui Yang , Yunhe Wang , Xinghao Chen , Boxin Shi , Chao Xu , Chunjing Xu , Qi Tian , Chang Xu

Neural networks are powerful and flexible models that work well for many difficult learning tasks in image, speech and natural language understanding. Despite their success, neural networks are still hard to design. In this paper, we use a…

Machine Learning · Computer Science 2017-02-16 Barret Zoph , Quoc V. Le

Large reasoning models such as DeepSeek-R1 and OpenAI o1 generate extended chains of thought spanning thousands of tokens, yet their integration with retrieval-augmented generation (RAG) remains fundamentally misaligned. Current RAG systems…

Information Retrieval · Computer Science 2026-04-30 Dongxin Guo , Jikun Wu , Siu Ming Yiu

Modeling and generating graphs is fundamental for studying networks in biology, engineering, and social sciences. However, modeling complex distributions over graphs and then efficiently sampling from these distributions is challenging due…

Machine Learning · Computer Science 2018-06-26 Jiaxuan You , Rex Ying , Xiang Ren , William L. Hamilton , Jure Leskovec

Enterprises grapple with the significant challenge of managing proprietary unstructured data, hindering efficient information retrieval. This has led to the emergence of AI-driven information retrieval solutions, designed to adeptly extract…

Search and retrieval remains a major research topic in several domains, including computer graphics, computer vision, engineering design, etc. A search engine requires primarily an input search query and a database of items to search from.…

Computer Vision and Pattern Recognition · Computer Science 2022-07-05 Bharadwaj Manda , Prasad Kendre , Subhrajit Dey , Ramanathan Muthuganapathy

The success of neural networks has driven a shift in focus from feature engineering to architecture engineering. However, successful networks today are constructed using a small and manually defined set of building blocks. Even in methods…

Machine Learning · Computer Science 2019-11-19 Mitchell Wortsman , Ali Farhadi , Mohammad Rastegari

Merging multiple expert models offers a promising approach for performing multi-task learning without accessing their original data. Existing methods attempt to alleviate task conflicts by sparsifying task vectors or promoting orthogonality…

Machine Learning · Computer Science 2025-05-27 Yongxian Wei , Anke Tang , Li Shen , Zixuan Hu , Chun Yuan , Xiaochun Cao

The rapid proliferation of artificial intelligence (AI) models and methods presents growing challenges for research software engineers and researchers who must select, integrate, and maintain appropriate models within complex research…

Deep learning models have proven to be successful in a wide range of machine learning tasks. Yet, they are often highly sensitive to perturbations on the input data which can lead to incorrect decisions with high confidence, hampering their…

Machine Learning · Computer Science 2023-06-13 Steffen Jung , Jovita Lukasik , Margret Keuper

Large pre-trained neural networks are ubiquitous and critical to the success of many downstream tasks in natural language processing and computer vision. However, within the field of web information retrieval, there is a stark contrast in…

Machine Learning · Computer Science 2022-10-28 Benedict Yeoh , Huijuan Wang

In this work, we focus on the problem of image instance retrieval with deep descriptors extracted from pruned Convolutional Neural Networks (CNN). The objective is to heavily prune convolutional edges while maintaining retrieval…

Computer Vision and Pattern Recognition · Computer Science 2017-07-19 Gaurav Manek , Jie Lin , Vijay Chandrasekhar , Lingyu Duan , Sateesh Giduthuri , Xiaoli Li , Tomaso Poggio

Recent progress in leveraging large language models (LLMs) has enabled Neural Architecture Design (NAD) systems to generate new architecture not limited from manually predefined search space. Nevertheless, LLM-driven generation remains…

Machine Learning · Computer Science 2025-12-08 Gyusam Chang , Jeongyoon Yoon , Shin han yi , JaeHyeok Lee , Sujin Jang , Sangpil Kim
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