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Pathology plays an important role in disease diagnosis, treatment decision-making and drug development. Previous works on interpretability for machine learning models on pathology images have revolved around methods such as attention value…

Vision foundation models (FMs) achieve state-of-the-art performance in medical imaging. However, they encode information in abstract latent representations that clinicians cannot interrogate or verify. The goal of this study is to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Philipp Wesp , Robbie Holland , Vasiliki Sideri-Lampretsa , Sergios Gatidis

Sparse autoencoders (SAEs) are useful for detecting and steering interpretable features in neural networks, with particular potential for understanding complex multimodal representations. Given their ability to uncover interpretable…

Computer Vision and Pattern Recognition · Computer Science 2025-05-29 Vladimir Zaigrajew , Hubert Baniecki , Przemyslaw Biecek

Sparse autoencoders (SAEs) emerged as a promising tool for mechanistic interpretability of transformer-based foundation models. Very recently, SAEs were also adopted for the visual domain, enabling the discovery of visual concepts and their…

Computer Vision and Pattern Recognition · Computer Science 2025-07-17 Muhammed Furkan Dasdelen , Hyesu Lim , Michele Buck , Katharina S. Götze , Carsten Marr , Steffen Schneider

To truly understand vision models, we must not only interpret their learned features but also validate these interpretations through controlled experiments. While earlier work offers either rich semantics or direct control, few post-hoc…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Samuel Stevens , Wei-Lun Chao , Tanya Berger-Wolf , Yu Su

Adapting foundation models for specific purposes has become a standard approach to build machine learning systems for downstream applications. Yet, it is an open question which mechanisms take place during adaptation. Here we develop a new…

Computer Vision and Pattern Recognition · Computer Science 2025-03-24 Hyesu Lim , Jinho Choi , Jaegul Choo , Steffen Schneider

Artificial intelligence in healthcare requires models that are accurate and interpretable. We advance mechanistic interpretability in medical vision by applying Medical Sparse Autoencoders (MedSAEs) to the latent space of MedCLIP, a…

Artificial Intelligence · Computer Science 2026-05-25 Riccardo Renzulli , Colas Lepoutre , Enrico Cassano , Marco Grangetto

Sparse Autoencoders (SAEs) provide potentials for uncovering structured, human-interpretable representations in Large Language Models (LLMs), making them a crucial tool for transparent and controllable AI systems. We systematically analyze…

Machine Learning · Computer Science 2026-02-03 Jack Gallifant , Shan Chen , Kuleen Sasse , Hugo Aerts , Thomas Hartvigsen , Danielle S. Bitterman

Sparse autoencoders (SAEs) have recently emerged as a powerful tool for interpreting the internal representations of large language models (LLMs), revealing latent latent features with semantical meaning. This interpretability has also…

Other Quantitative Biology · Quantitative Biology 2025-07-11 Haoxiang Guan , Jiyan He , Jie Zhang

Interpretability can improve the safety, transparency and trust of AI models, which is especially important in healthcare applications where decisions often carry significant consequences. Mechanistic interpretability, particularly through…

Sparse autoencoders (SAEs) have lately been used to uncover interpretable latent features in large language models. By projecting dense embeddings into a much higher-dimensional and sparse space, learned features become disentangled and…

Machine Learning · Computer Science 2025-07-30 Viktoria Schuster

The rapid advancements in transformer-based language models have revolutionized natural language processing, yet understanding the internal mechanisms of these models remains a significant challenge. This paper explores the application of…

Machine Learning · Computer Science 2025-02-14 Edith Natalia Villegas Garcia , Alessio Ansuini

Analyzing large-scale text corpora is a core challenge in machine learning, crucial for tasks like identifying undesirable model behaviors or biases in training data. Current methods often rely on costly LLM-based techniques (e.g.…

Artificial Intelligence · Computer Science 2025-12-12 Nick Jiang , Xiaoqing Sun , Lisa Dunlap , Lewis Smith , Neel Nanda

Sparse Autoencoders (SAEs) have emerged as a powerful framework for machine learning interpretability, enabling the unsupervised decomposition of model representations into a dictionary of abstract, human-interpretable concepts. However, we…

Computer Vision and Pattern Recognition · Computer Science 2025-05-27 Thomas Fel , Ekdeep Singh Lubana , Jacob S. Prince , Matthew Kowal , Victor Boutin , Isabel Papadimitriou , Binxu Wang , Martin Wattenberg , Demba Ba , Talia Konkle

Sparse Autoencoder (SAE) has emerged as a powerful tool for mechanistic interpretability of large language models. Recent works apply SAE to protein language models (PLMs), aiming to extract and analyze biologically meaningful features from…

Quantitative Methods · Quantitative Biology 2026-01-21 Xiangyu Liu , Haodi Lei , Yi Liu , Yang Liu , Wei Hu

While large language models provide strong compositional reasoning, existing reasoning segmentation pipelines fail to transparently connect this reasoning to visual perception. Current methods, such as latent query alignment, are end-to-end…

Computer Vision and Pattern Recognition · Computer Science 2026-05-22 Zhenyu Lu , Liupeng Li , Jinpeng Wang , Haoqian Kang , Yan Feng , Ke Chen , Yaowei Wang

Sparse Autoencoders (SAEs) have been successfully used to probe Large Language Models (LLMs) and extract interpretable concepts from their internal representations. These concepts are linear combinations of neuron activations that…

Computation and Language · Computer Science 2026-02-23 Mathis Le Bail , Jérémie Dentan , Davide Buscaldi , Sonia Vanier

While the activations of neurons in deep neural networks usually do not have a simple human-understandable interpretation, sparse autoencoders (SAEs) can be used to transform these activations into a higher-dimensional latent space which…

Machine Learning · Computer Science 2025-08-07 Gonçalo Paulo , Alex Mallen , Caden Juang , Nora Belrose

Many current state-of-the-art models for sequential recommendations are based on transformer architectures. Interpretation and explanation of such black box models is an important research question, as a better understanding of their…

Information Retrieval · Computer Science 2026-02-18 Anton Klenitskiy , Konstantin Polev , Daria Denisova , Alexey Vasilev , Dmitry Simakov , Gleb Gusev

Understanding and mitigating the potential risks associated with foundation models (FMs) hinges on developing effective interpretability methods. Sparse Autoencoders (SAEs) have emerged as a promising tool for disentangling FM…

Machine Learning · Computer Science 2024-11-04 Aashiq Muhamed , Mona Diab , Virginia Smith
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