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Modeling the relationship between chemical structure and molecular activity is a key goal in drug development. Many benchmark tasks have been proposed for molecular property prediction, but these tasks are generally aimed at specific,…

Quantitative Methods · Quantitative Biology 2020-10-05 Samuel G. Finlayson , Matthew B. A. McDermott , Alex V. Pickering , Scott L. Lipnick , Isaac S. Kohane

Design patterns (DPs) are recognised as a good practice in software development. However, the lack of appropriate documentation often hampers traceability, and their benefits are blurred among thousands of lines of code. Automatic methods…

Software Engineering · Computer Science 2024-01-17 Rafael Barbudo , Aurora Ramírez , Francisco Servant , José Raúl Romero

Histopathology image analysis plays a critical role in cancer diagnosis and treatment. To automatically segment the cancerous regions, fully supervised segmentation algorithms require labor-intensive and time-consuming labeling at the pixel…

Image and Video Processing · Electrical Eng. & Systems 2019-08-29 Gang Xu , Zhigang Song , Zhuo Sun , Calvin Ku , Zhe Yang , Cancheng Liu , Shuhao Wang , Jianpeng Ma , Wei Xu

The field of advanced text-to-image generation is witnessing the emergence of unified frameworks that integrate powerful text encoders, such as CLIP and T5, with Diffusion Transformer backbones. Although there have been efforts to control…

Computer Vision and Pattern Recognition · Computer Science 2025-02-28 Liang Chen , Shuai Bai , Wenhao Chai , Weichu Xie , Haozhe Zhao , Leon Vinci , Junyang Lin , Baobao Chang

Due to the rapid advancements of sensory and computing technology, multi-modal data sources that represent the same pattern or phenomenon have attracted growing attention. As a result, finding means to explore useful information from these…

Machine Learning · Computer Science 2021-03-10 Lei Gao , Ling Guan

Histopathological image segmentation is a laborious and time-intensive task, often requiring analysis from experienced pathologists for accurate examinations. To reduce this burden, supervised machine-learning approaches have been adopted…

Computer Vision and Pattern Recognition · Computer Science 2024-09-12 Vishnuvardhan Purma , Suhas Srinath , Seshan Srirangarajan , Aanchal Kakkar , Prathosh A. P

Current SMILES-based diffusion models for molecule generation typically support only unimodal constraint. They inject conditioning signals at the start of the training process and require retraining a new model from scratch whenever the…

Machine Learning · Computer Science 2025-08-21 Yunzhe Zhang , Yifei Wang , Khanh Vinh Nguyen , Pengyu Hong

Recent progress in large language models (LLMs) has leveraged their in-context learning (ICL) abilities to enable quick adaptation to unseen biomedical NLP tasks. By incorporating only a few input-output examples into prompts, LLMs can…

Computation and Language · Computer Science 2025-08-12 Jun Wang , Zaifu Zhan , Qixin Zhang , Mingquan Lin , Meijia Song , Rui Zhang

Manifold learning (ML) aims to seek low-dimensional embedding from high-dimensional data. The problem is challenging on real-world datasets, especially with under-sampling data, and we find that previous methods perform poorly in this case.…

Machine Learning · Computer Science 2022-07-27 Zelin Zang , Siyuan Li , Di Wu , Ge Wang , Lei Shang , Baigui Sun , Hao Li , Stan Z. Li

Huge amount of applications in various fields, such as gene expression analysis or computer vision, undergo data sets with high-dimensional low-sample-size (HDLSS), which has putted forward great challenges for standard statistical and…

Machine Learning · Computer Science 2022-06-07 Liran Shen , Meng Joo Er , Qingbo Yin

Recent advancements in Large Multimodal Models (LMMs) have attracted interest in their generalization capability with only a few samples in the prompt. This progress is particularly relevant to the medical domain, where the quality and…

Computation and Language · Computer Science 2024-05-06 Seonhee Cho , Choonghan Kim , Jiho Lee , Chetan Chilkunda , Sujin Choi , Joo Heung Yoon

In the genomic era, the identification of gene signatures associated with disease is of significant interest. Such signatures are often used to predict clinical outcomes in new patients and aid clinical decision-making. However, recent…

Methodology · Statistics 2019-03-27 Naim U. Rashid , Quefeng Li , Jen Jen Yeh , Joseph G. Ibrahim

To perform unconstrained face recognition robust to variations in illumination, pose and expression, this paper presents a new scheme to extract "Multi-Directional Multi-Level Dual-Cross Patterns" (MDML-DCPs) from face images. Specifically,…

Computer Vision and Pattern Recognition · Computer Science 2015-08-07 Changxing Ding , Jonghyun Choi , Dacheng Tao , Larry S. Davis

Datacenters are increasingly becoming heterogeneous, and are starting to include specialized hardware for networking, video processing, and especially deep learning. To leverage the heterogeneous compute capability of modern datacenters, we…

Machine Learning · Computer Science 2023-08-03 Yassine Ghannane , Mohamed S. Abdelfattah

In this work, we study distance metric learning (DML) for high dimensional data. A typical approach for DML with high dimensional data is to perform the dimensionality reduction first before learning the distance metric. The main…

Machine Learning · Computer Science 2015-09-16 Qi Qian , Rong Jin , Lijun Zhang , Shenghuo Zhu

Distance metric learning (DML) approaches learn a transformation to a representation space where distance is in correspondence with a predefined notion of similarity. While such models offer a number of compelling benefits, it has been…

Machine Learning · Statistics 2016-03-03 Oren Rippel , Manohar Paluri , Piotr Dollar , Lubomir Bourdev

Deep learning techniques have become widely utilized in histopathology image classification due to their superior performance. However, this success heavily relies on the availability of substantial labeled data, which necessitates…

Image and Video Processing · Electrical Eng. & Systems 2024-10-15 Meng Li , Chaoyi Li , Can Peng , Brian C. Lovell

Human multimodal emotion recognition (MER) seeks to infer human emotions by integrating information from language, visual, and acoustic modalities. Although existing MER approaches have achieved promising results, they still struggle with…

Computer Vision and Pattern Recognition · Computer Science 2026-02-05 Yong Li , Yuanzhi Wang , Yi Ding , Shiqing Zhang , Ke Lu , Cuntai Guan

Recent advances in vision-language models have significantly expanded the frontiers of automated image analysis. However, applying these models in safety-critical contexts remains challenging due to the complex relationships between…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Muhammad Imran , Yugyung Lee

described by multiple instances (e.g., image patches) and simultaneously associated with multiple labels. Existing MIML methods are useful in many applications but most of which suffer from relatively low accuracy and training efficiency…

Computer Vision and Pattern Recognition · Computer Science 2023-06-16 Qi Lai , Jianhang Zhou , Yanfen Gan , Chi-Man Vong , Deshuang Huang
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