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The use of deep learning (DL) in medical image analysis has significantly improved the ability to predict lung cancer. In this study, we introduce a novel deep convolutional neural network (CNN) model, named ResNet+, which is based on the…

Image and Video Processing · Electrical Eng. & Systems 2025-07-03 Ahmad Chaddad , Jihao Peng , Yihang Wu

Nasopharyngeal Carcinoma (NPC) is a malignant epithelial cancer arising from the nasopharynx. Survival prediction is a major concern for NPC patients, as it provides early prognostic information to plan treatments. Recently, deep survival…

Image and Video Processing · Electrical Eng. & Systems 2022-09-20 Mingyuan Meng , Bingxin Gu , Lei Bi , Shaoli Song , David Dagan Feng , Jinman Kim

Survival analysis aims to model how covariates and time jointly shape the time-to-event distribution under right censoring. Classical methods such as the Cox model and generalised additive models (GAMs) require interactions and time-varying…

Machine Learning · Statistics 2026-05-26 Stelios Boulitsakis Logothetis , Angela Wood , Pietro Liò

This study explores the application potential of a deep learning model based on the CNN-LSTM framework in forecasting the sales volume of cancer drugs, with a focus on modeling complex time series data. As advancements in medical technology…

Computational Engineering, Finance, and Science · Computer Science 2025-06-30 Yinghan Li , Yilin Yao , Junghua Lin , Nanxi Wang

In this paper, we apply a general deep learning (DL) framework for the answer selection task, which does not depend on manually defined features or linguistic tools. The basic framework is to build the embeddings of questions and answers…

Computation and Language · Computer Science 2016-03-29 Ming Tan , Cicero dos Santos , Bing Xiang , Bowen Zhou

Survival analysis aims at modeling the relationship between covariates and event occurrence with some untracked (censored) samples. In implementation, existing methods model the survival distribution with strong assumptions or in a discrete…

Machine Learning · Computer Science 2023-05-25 Yu Ling , Weimin Tan , Bo Yan

In the context of survival analysis, data-driven neural network-based methods have been developed to model complex covariate effects. While these methods may provide better predictive performance than regression-based approaches, not all…

Machine Learning · Statistics 2024-04-23 Jesse Islam , Maxime Turgeon , Robert Sladek , Sahir Bhatnagar

Deep reinforcement learning (RL) policies can demonstrate unsafe behaviors and are challenging to interpret. To address these challenges, we combine RL policy model checking--a technique for determining whether RL policies exhibit unsafe…

Artificial Intelligence · Computer Science 2025-01-07 Dennis Gross , Helge Spieker

There exists unexplained diverse variation within the predefined colon cancer stages using only features either from genomics or histopathological whole slide images as prognostic factors. Unraveling this variation will bring about improved…

Quantitative Methods · Quantitative Biology 2022-12-15 Olalekan Ogundipe , Zeyneb Kurt , Wai Lok Woo

Copulas provide an attractive approach for constructing multivariate distributions with flexible marginal distributions and different forms of dependences. Of particular importance in many areas is the possibility of explicitly forecasting…

Methodology · Statistics 2018-05-22 Feng Li , Yanfei Kang

Rising breast cancer (BC) occurrence and mortality are major global concerns for women. Deep learning (DL) has demonstrated superior diagnostic performance in BC classification compared to human expert readers. However, the predominant use…

In this study, we present a hybrid CNN-RNN approach to investigate long-term survival of subjects in a lung cancer screening study. Subjects who died of cardiovascular and respiratory causes were identified whereby the CNN model was used to…

Machine Learning · Computer Science 2023-03-21 Yaozhi Lu , Shahab Aslani , An Zhao , Ahmed Shahin , David Barber , Mark Emberton , Daniel C. Alexander , Joseph Jacob

Deep Brain Stimulation (DBS) has gained increasing attention as an effective method to mitigate Parkinsons disease (PD) disorders. Existing DBS systems are open-loop such that the system parameters are not adjusted automatically based on…

Computer Vision and Pattern Recognition · Computer Science 2016-11-18 Hosein M. Golshan , Adam O. Hebb , Sara J. Hanrahan , Joshua Nedrud , Mohammad H. Mahoor

Deep learning (DL) analysis of Chest X-ray (CXR) and Computed tomography (CT) images has garnered a lot of attention in recent times due to the COVID-19 pandemic. Convolutional Neural Networks (CNNs) are well suited for the image analysis…

Image and Video Processing · Electrical Eng. & Systems 2022-12-29 Suba S , Nita Parekh

Traditional statistical and machine learning methods typically assume that the training and test data follow the same distribution. However, this assumption is frequently violated in real-world applications, where the training data in the…

Methodology · Statistics 2025-07-08 Hanxuan Ye , Hongzhe Li

Objective: Survival analysis is central to medical prediction, yet large language models (LLMs) are rarely used as end-to-end survival models because censoring prevents straightforward supervised fine-tuning. Here we present LLMSurvival, a…

Artificial Intelligence · Computer Science 2026-05-26 Yishu Wei , Hexin Dong , Yi Lin , Jiahe Qian , Yi Liu , Yifan Peng

Lung cancer is the leading cause of cancer-related mortality worldwide. Lung cancer screening (LCS) using annual low-dose computed tomography (CT) scanning has been proven to significantly reduce lung cancer mortality by detecting cancerous…

Recent studies have highlighted the high correlation between cardiovascular diseases (CVD) and lung cancer, and both are associated with significant morbidity and mortality. Low-Dose CT (LCDT) scans have led to significant improvements in…

Computer Vision and Pattern Recognition · Computer Science 2019-11-27 Hengtao Guo , Uwe Kruger , Ge Wang , Mannudeep K. Kalra , Pingkun Yan

Accurate survival prediction in head and neck cancer (HNC) is essential for guiding clinical decision-making and optimizing treatment strategies. Traditional models, such as Cox proportional hazards, have been widely used but are limited in…

Computer Vision and Pattern Recognition · Computer Science 2024-10-30 Aiman Farooq , Utkarsh Sharma , Deepak Mishra

Deep neural networks (DNNs) have become powerful tools for modeling complex data structures through sequentially integrating simple functions in each hidden layer. In survival analysis, recent advances of DNNs primarily focus on enhancing…

Machine Learning · Statistics 2025-03-26 Changhui Yuan , Shishun Zhao , Shuwei Li , Xinyuan Song , Zhao Chen