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Security applications are increasingly relying on large language models (LLMs) for cyber threat detection; however, their opaque reasoning often limits trust, particularly in decisions that require domain-specific cybersecurity knowledge.…

Cryptography and Security · Computer Science 2025-11-03 Arnabh Borah , Md Tanvirul Alam , Nidhi Rastogi

This study leverages optimized context retrieval to enhance open-source Large Language Models (LLMs) for cost-effective, high performance healthcare AI. We demonstrate that this approach achieves state-of-the-art accuracy on medical…

Artificial Intelligence · Computer Science 2025-04-04 Jordi Bayarri-Planas , Ashwin Kumar Gururajan , Dario Garcia-Gasulla

Large language models (LLMs) in biomedicine face a fundamental conflict between static parameter knowledge and the dynamic nature of clinical evidence. Retrieval-Augmented Generation (RAG) addresses this by grounding generation in external…

Other Quantitative Biology · Quantitative Biology 2025-12-19 Jiawei He , Boya Zhang , Hossein Rouhizadeh , Yingjian Chen , Rui Yang , Jin Lu , Xudong Chen , Nan Liu , Douglas Teodoro

Despite the potential of Large Language Models (LLMs) in medicine, they may generate responses lacking supporting evidence or based on hallucinated evidence. While Retrieval Augment Generation (RAG) is popular to address this issue, few…

As Large Language Models (LLMs) are increasingly integrated into healthcare to address complex inquiries, ensuring their reliability remains a critical challenge. Recent studies have highlighted that generic LLMs often struggle in clinical…

Computation and Language · Computer Science 2026-04-01 Bian Sun , Zhenjian Wang , Orvill de la Torre , Zirui Wang

Generating high-quality answers consistently by providing contextual information embedded in the prompt passed to the Large Language Model (LLM) is dependent on the quality of information retrieval. As the corpus of contextual information…

Information Retrieval · Computer Science 2024-08-01 Sai Ganesh , Anupam Purwar , Gautam B

The adoption of large language models (LLMs) to assist clinicians has attracted remarkable attention. Existing works mainly adopt the close-ended question-answering (QA) task with answer options for evaluation. However, many clinical…

Current ophthalmology clinical workflows are plagued by over-referrals, long waits, and complex and heterogeneous medical records. Large language models (LLMs) present a promising solution to automate various procedures such as triaging,…

As connected and automated transportation systems evolve, there is a growing need for federal and state authorities to revise existing laws and develop new statutes to address emerging cybersecurity and data privacy challenges. This study…

The adoption of generative AI and large language models (LLMs) in education is still emerging. In this study, we explore the development and evaluation of AI teaching assistants that provide curriculum-based guidance using a…

Computation and Language · Computer Science 2025-10-06 Konstantinos Katharakis , Sippo Rossi , Raghava Rao Mukkamala

Large Language Models (LLMs) are increasingly used for clinical decision support, where hallucinations and unsafe suggestions may pose direct risks to patient safety. These risks are hard to assess: subtle clinical errors are often missed…

Computation and Language · Computer Science 2026-05-14 Yinzhu Chen , Abdine Maiga , Hossein A. Rahmani , Emine Yilmaz

The versatility of large language models (LLMs) has been explored across various sectors, but their application in healthcare poses challenges, particularly in the domain of pharmaceutical contraindications where accurate and reliable…

Artificial Intelligence · Computer Science 2025-08-11 Byeonghun Bang , Jongsuk Yoon , Dong-Jin Chang , Seho Park , Yong Oh Lee

Large Language Models (LLMs) have demonstrated significant promise for various applications in healthcare. However, their efficacy in the Arabic medical domain remains unexplored due to the lack of high-quality domain-specific datasets and…

Computation and Language · Computer Science 2025-08-25 Mouath Abu Daoud , Chaimae Abouzahir , Leen Kharouf , Walid Al-Eisawi , Nizar Habash , Farah E. Shamout

Recent advancements in Large Language Models (LLMs) and Large Vision Language Models (LVLMs) have enabled general-purpose systems to demonstrate promising capabilities in complex reasoning tasks, including those in the medical domain.…

Computation and Language · Computer Science 2026-05-19 Rafid Ahmed , Intesar Tahmid , Mir Sazzat Hossain , Tasnimul Hossain Tomal , Md Fahim , Md Farhad Alam Bhuiyan

Unlike professional caregivers, family caregivers often assume this role without formal preparation or training. Because of this, there is an urgent need to enhance the capacity of family caregivers to provide quality care. Large language…

Computation and Language · Computer Science 2024-03-12 Bambang Parmanto , Bayu Aryoyudanta , Wilbert Soekinto , I Made Agus Setiawan , Yuhan Wang , Haomin Hu , Andi Saptono , Yong K. Choi

This paper introduces a system that integrates large language models (LLMs) into the clinical trial retrieval process, enhancing the effectiveness of matching patients with eligible trials while maintaining information privacy and allowing…

Information Retrieval · Computer Science 2024-11-01 Georgios Peikos , Pranav Kasela , Gabriella Pasi

Background The increasing adoption of Artificial Intelligence (AI) in healthcare has sparked growing concerns about its environmental and ethical implications. Commercial Large Language Models (LLMs), such as ChatGPT and DeepSeek, require…

Artificial Intelligence · Computer Science 2025-06-26 Konstantinos Vrettos , Michail E. Klontzas

Access to the right evidence does not guarantee that large language models (LLMs) will reason with it correctly. This gap between retrieval and reasoning is especially concerning in clinical settings, where outputs must align with…

Artificial Intelligence · Computer Science 2025-11-21 Deepthi Potluri , Aby Mammen Mathew , Jeffrey B DeWitt , Alexander L. Rasgon , Yide Hao , Junyuan Hong , Ying Ding

Incorporating large language models (LLMs) in medical question answering demands more than high average accuracy: a model that returns substantively different answers each time it is queried is not a reliable medical tool. Online health…

Information Retrieval · Computer Science 2026-04-14 Avi-ad Avraam Buskila

Deploying Large Language Model (LLM) applications, particularly those relying on Retrieval-Augmented Generation (RAG), remains challenging due to high computational demands, outdated knowledge bases, and the need to manually select optimal…