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Related papers: Efficient Whole Slide Pathology VQA via Token Comp…

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Recent advancements in computational pathology have produced patch-level Multi-modal Large Language Models (MLLMs), but these models are limited by their inability to analyze whole slide images (WSIs) comprehensively and their tendency to…

Computer Vision and Pattern Recognition · Computer Science 2025-08-13 Yuci Liang , Xinheng Lyu , Wenting Chen , Meidan Ding , Jipeng Zhang , Xiangjian He , Song Wu , Xiaohan Xing , Sen Yang , Xiyue Wang , Linlin Shen

Computational pathology and whole-slide image (WSI) analysis are pivotal in cancer diagnosis and prognosis. However, the ultra-high resolution of WSIs presents significant modeling challenges. Recent advancements in pathology foundation…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Honglin Li , Zhongyi Shui , Yunlong Zhang , Chenglu Zhu , Lin Yang

The application of large vision-language models to computational pathology holds great promise for diagnostic assistants but faces a critical computational bottleneck: the gigapixel scale of Whole Slide Images (WSIs). A single WSI typically…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Zhuo Chen , Shawn Young , Lijian Xu

Multi-modal large language models (MLLMs) utilizing instruction-following data, such as LLaVA, have achieved great progress in the industry. A major limitation in these models is that visual tokens consume a substantial portion of the…

Computer Vision and Pattern Recognition · Computer Science 2024-12-13 Ke Wang , Hong Xuan

Whole Slide Image (WSI) MLLMs are difficult to build and deploy because gigapixel slides induce thousands of visual tokens, while only a small fraction of regions is diagnostically relevant. Existing slide-level pathology MLLMs typically…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Qingqiao Hu , Weimin Lyu , Meilong Xu , Kehan Qi , Xiaoling Hu , Saumya Gupta , Jiawei Zhou , Chao Chen

In Computational Pathology (CPath), the introduction of Vision-Language Models (VLMs) has opened new avenues for research, focusing primarily on aligning image-text pairs at a single magnification level. However, this approach might not be…

Computer Vision and Pattern Recognition · Computer Science 2025-04-29 Shahad Albastaki , Anabia Sohail , Iyyakutti Iyappan Ganapathi , Basit Alawode , Asim Khan , Sajid Javed , Naoufel Werghi , Mohammed Bennamoun , Arif Mahmood

Whole Slide Images (WSIs) exhibit hierarchical structure, where diagnostic information emerges from cellular morphology, regional tissue organization, and global context. Existing Computational Pathology (CPath) Multimodal Large Language…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Basit Alawode , Arif Mahmood , Muaz Khalifa Al-Radi , Shahad Albastaki , Asim Khan , Muhammad Bilal , Moshira Ali Abdalla , Mohammed Bennamoun , Sajid Javed

Whole slide imaging is routinely adopted for carcinoma diagnosis and prognosis. Abundant experience is required for pathologists to achieve accurate and reliable diagnostic results of whole slide images (WSI). The huge size and…

Computer Vision and Pattern Recognition · Computer Science 2024-07-09 Pingyi Chen , Chenglu Zhu , Sunyi Zheng , Honglin Li , Lin Yang

Large Multimodal Models (LMMs) have shown significant visual reasoning capabilities by connecting a visual encoder and a large language model. LMMs typically take in a fixed and large amount of visual tokens, such as the penultimate layer…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Yuzhang Shang , Mu Cai , Bingxin Xu , Yong Jae Lee , Yan Yan

Hepatocellular Carcinoma diagnosis relies heavily on the interpretation of gigapixel Whole Slide Images. However, current computational approaches are constrained by fixed-resolution processing mechanisms and inefficient feature…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Yuxuan Yang , Zhonghao Yan , Yi Zhang , Bo Yun , Muxi Diao , Guowei Zhao , Kongming Liang , Wenbin Li , Zhanyu Ma

Vision-Language Models (VLMs) have achieved remarkable success in various multi-modal tasks, but they are often bottlenecked by the limited context window and high computational cost of processing high-resolution image inputs and videos.…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Xubing Ye , Yukang Gan , Xiaoke Huang , Yixiao Ge , Yansong Tang

The architecture of multimodal large language models (MLLMs) commonly connects a vision encoder, often based on CLIP-ViT, to a large language model. While CLIP-ViT works well for capturing global image features, it struggles to model local…

Computer Vision and Pattern Recognition · Computer Science 2025-07-08 Haoran Lou , Chunxiao Fan , Ziyan Liu , Yuexin Wu , Xinliang Wang

The rapidly emerging field of computational pathology has the potential to enable objective diagnosis, therapeutic response prediction and identification of new morphological features of clinical relevance. However, deep learning-based…

Image and Video Processing · Electrical Eng. & Systems 2020-05-25 Ming Y. Lu , Drew F. K. Williamson , Tiffany Y. Chen , Richard J. Chen , Matteo Barbieri , Faisal Mahmood

Large Vision-Language Models (LVLMs) excel in visual understanding and reasoning, but the excessive visual tokens lead to high inference costs. Although recent token reduction methods mitigate this issue, they mainly target single-turn…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Yi Wang , Haofei Zhang , Qihan Huang , Anda Cao , Gongfan Fang , Wei Wang , Xuan Jin , Jie Song , Mingli Song , Xinchao Wang

Recent methods have made notable progress in accelerating Large Vision-Language Models (LVLMs) by exploiting the inherent redundancy in visual inputs. Most existing approaches, however, focus narrowly on reducing image tokens before or…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Lianyu Hu , Liqing Gao , Fanhua Shang , Liang Wan , Wei Feng

Histopathology whole slide images (WSIs) play a very important role in clinical studies and serve as the gold standard for many cancer diagnoses. However, generating automatic tools for processing WSIs is challenging due to their enormous…

Computer Vision and Pattern Recognition · Computer Science 2022-09-28 Jingwei Zhang , Xin Zhang , Ke Ma , Rajarsi Gupta , Joel Saltz , Maria Vakalopoulou , Dimitris Samaras

In this paper, we present LLaVA-Scissor, a training-free token compression strategy designed for video multimodal large language models. Previous methods mostly attempt to compress tokens based on attention scores, but fail to effectively…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Boyuan Sun , Jiaxing Zhao , Xihan Wei , Qibin Hou

Recent advances on Multi-modal Large Language Models have demonstrated that high-resolution image input is crucial for model capabilities, especially for fine-grained tasks. However, high-resolution images lead to a quadratic increase in…

Computer Vision and Pattern Recognition · Computer Science 2024-11-22 Yuke Zhu , Chi Xie , Shuang Liang , Bo Zheng , Sheng Guo

In recent years, large-scale vision-language models (VLMs) have demonstrated remarkable performance on multimodal understanding and reasoning tasks. However, handling high-dimensional visual features often incurs substantial computational…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Xiaoyang Guo , Keze Wang

The advent of real-time large multimodal models (LMMs) like GPT-4o has sparked considerable interest in efficient LMMs. LMM frameworks typically encode visual inputs into vision tokens (continuous representations) and integrate them and…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Shaolei Zhang , Qingkai Fang , Zhe Yang , Yang Feng
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