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Background: Beam angle optimization (BAO) is a critical component of radiation therapy (RT) treatment planning, where small changes in beam configuration can significantly impact treatment quality, especially for proton RT. Mathematically,…

Medical Physics · Physics 2025-09-08 Nimita Shinde , Ya-Nan Zhu , Haozheng Shen , Hao Gao

In this paper, we study the use of hybrid classical-quantum annealing technology to solve a critical business optimization problem that is a form of multiproduct multi-bin packing in three dimensions with support constraints and case…

Optimization and Control · Mathematics 2024-08-29 Mohsen Rahmani , Nitish Umang , Mason Christensen

Quantum computing (QC) has gained popularity due to its unique capabilities that are quite different from that of classical computers in terms of speed and methods of operations. This paper proposes hybrid models and methods that…

Quantum Physics · Physics 2019-11-12 Akshay Ajagekar , Travis Humble , Fengqi You

Current quantum computers can only solve optimization problems of a very limited size. For larger problems, decomposition methods are required in which the original problem is broken down into several smaller sub-problems. These are then…

Optimization and Control · Mathematics 2025-04-30 Zongji Li , Tobias Seidel , Michael Bortz , Raoul Heese

Quantum computers show potential for achieving computational advantage over classical computers, with many candidate applications in combinatorial optimisation. We present an application level benchmarking framework for near-term quantum…

The emergence of huge-scale, data-intensive linear optimization (LO) problems in applications such as machine learning has driven the need for more computationally efficient interior point methods (IPMs). While conventional IPMs are…

This paper introduces D2-UC, a quantum-ready framework for the unit commitment (UC) problem that prepares UC for near-term hybrid quantum-classical solvers by combining distributed classical decomposition with distributed quantum execution.…

Quantum Physics · Physics 2025-11-06 Milad Hasanzadeh , Amin Kargarian

Quantum annealing has emerged as a promising approach for solving NP-hard optimization problems, leveraging quantum phenomena such as quantum tunneling to navigate complex energy landscapes. However, the extent to which quantum tunneling…

Quantum Physics · Physics 2026-03-02 Vishwajeet Ohal , Pierre Boulanger

With unprecedented increases in traffic load in today's wireless networks, design challenges shift from the wireless network itself to the computational support behind the wireless network. In this vein, there is new interest in…

Networking and Internet Architecture · Computer Science 2020-10-05 Minsung Kim , Davide Venturelli , Kyle Jamieson

The advent of quantum algorithms has initiated a discourse on the potential for quantum speedups for optimization problems. However, several factors still hinder a practical realization of the potential benefits. These include the lack of…

Real-world optimization problems must undergo a series of transformations before becoming solvable on current quantum hardware. Even for a fixed problem, the number of possible transformation paths -- from industry-relevant formulations…

McGeoch and Wang (2013) recently obtained optimal or near-optimal solutions to some quadratic unconstrained boolean optimization (QUBO) problem instances using a 439 qubit D-Wave Two quantum computing system in much less time than with the…

Optimization and Control · Mathematics 2015-11-05 Sanjeeb Dash

Database systems encompass several performance-critical optimization tasks, such as join ordering and index tuning. As data volumes grow and workloads become more complex, these problems have become exponentially harder to solve…

Databases · Computer Science 2026-01-21 Hanwen Liu , Ibrahim Sabek

Optimization problems is one of the most challenging applications of quantum computers, as well as one of the most relevants. As a consequence, it has attracted huge efforts to obtain a speedup over classical algorithms using quantum…

We present a new framework for solving general topology optimization (TO) problems that find an optimal material distribution within a design space to maximize the performance of a structure while satisfying design constraints. These…

Numerical Analysis · Mathematics 2024-11-20 Zisheng Ye , Wenxiao Pan

This tutorial offers a quick, hands-on introduction to solving Quadratic Unconstrained Binary Optimization (QUBO) models on currently available quantum computers and their simulators. We cover both IBM and D-Wave machines: IBM utilizes a…

Quantum Physics · Physics 2025-06-18 Arul Mazumder , Sridhar Tayur

Inspired by recent developments in various areas of science relevant to quantum computing, we introduce quantum manifold optimization (QMO) as a promising framework for solving constrained optimization problems in next-generation wireless…

Signal Processing · Electrical Eng. & Systems 2025-04-15 Getuar Rexhepi , Hyeon Seok Rou , Giuseppe Thadeu Freitas de Abreu

Iterative Refinement (IR) is a classical computing technique for obtaining highly precise solutions to linear systems of equations, as well as linear optimization problems. In this paper, motivated by the limited precision of quantum…

Optimization and Control · Mathematics 2023-12-19 Mohammadhossein Mohammadisiahroudi , Brandon Augustino , Pouya Sampourmahani , Tamás Terlaky

Emerging quantum processors provide an opportunity to explore new approaches for solving traditional problems in the post Moore's law supercomputing era. However, the limited number of qubits makes it infeasible to tackle massive real-world…

Partitioning transportation networks into balanced and spatially coherent traffic zones is a fundamental yet computationally challenging task in intelligent transportation systems. The resulting optimization problem exhibits dense…

Quantum Physics · Physics 2026-05-19 Ruimin Ke , Talha Azfar , Kaicong Huang , Shuyang Li