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Related papers: BioGraphFusion: Graph Knowledge Embedding for Biol…

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Knowledge graph is a popular format for representing knowledge, with many applications to semantic search engines, question-answering systems, and recommender systems. Real-world knowledge graphs are usually incomplete, so knowledge graph…

Machine Learning · Computer Science 2023-04-26 Hung Nghiep Tran , Atsuhiro Takasu

Knowledge Graphs (KG) and associated Knowledge Graph Embedding (KGE) models have recently begun to be explored in the context of drug discovery and have the potential to assist in key challenges such as target identification. In the drug…

Biomolecules · Quantitative Biology 2022-06-01 Stephen Bonner , Ian P Barrett , Cheng Ye , Rowan Swiers , Ola Engkvist , Charles Tapley Hoyt , William L Hamilton

Biomedical knowledge graphs are increasingly large, dynamic, and multimodal, driven by rapid advances in biotechnology such as high-throughput sequencing. Machine learning models can infer previously unobserved biomedical relationships and…

Machine Learning · Computer Science 2026-05-12 Yousef A. Radwan , Yao Li , Qing Qing , Ziqi Xu , Qixin Zhang , Yongcheng Jing , Renqiang Luo , Xikun Zhang

As an efficient model for knowledge organization, the knowledge graph has been widely adopted in several fields, e.g., biomedicine, sociology, and education. And there is a steady trend of learning embedding representations of knowledge…

Computation and Language · Computer Science 2024-04-01 Siyu Yao , Ruijie Wang , Shen Sun , Derui Bu , Jun Liu

Entity synonyms discovery is crucial for entity-leveraging applications. However, existing studies suffer from several critical issues: (1) the input mentions may be out-of-vocabulary (OOV) and may come from a different semantic space of…

Artificial Intelligence · Computer Science 2021-04-02 Yiying Yang , Xi Yin , Haiqin Yang , Xingjian Fei , Hao Peng , Kaijie Zhou , Kunfeng Lai , Jianping Shen

The ability of knowledge graphs to represent complex relationships at scale has led to their adoption for various needs including knowledge representation, question-answering, and recommendation systems. Knowledge graphs are often…

Computation and Language · Computer Science 2023-05-18 Jason Youn , Ilias Tagkopoulos

Embedding knowledge graphs (KGs) for multi-hop logical reasoning is a challenging problem due to massive and complicated structures in many KGs. Recently, many promising works projected entities and queries into a geometric space to…

Machine Learning · Computer Science 2023-04-25 Dong Yang , Peijun Qing , Yang Li , Haonan Lu , Xiaodong Lin

Integrating heterogeneous biomedical data including imaging, omics, and clinical records supports accurate diagnosis and personalised care. Graph-based models fuse such non-Euclidean data by capturing spatial and relational structure, yet…

Genomics · Quantitative Biology 2025-05-06 Alireza Sadeghi , Farshid Hajati , Ahmadreza Argha , Nigel H Lovell , Min Yang , Hamid Alinejad-Rokny

Knowledge graphs and structural causal models have each proven valuable for organizing biomedical knowledge and estimating causal effects, but remain largely disconnected: knowledge graphs encode qualitative relationships focusing on facts…

Artificial Intelligence · Computer Science 2025-05-13 Sumyyah Toonsi , Paul Schofield , Robert Hoehndorf

Biomedical information graphs are crucial for interaction discovering of biomedical information in modern age, such as identification of multifarious molecular interactions and drug discovery, which attracts increasing interests in…

Machine Learning · Computer Science 2024-02-20 Zecheng Yin

Large language models (LLMs) are transforming the way information is retrieved with vast amounts of knowledge being summarized and presented via natural language conversations. Yet, LLMs are prone to highlight the most frequently seen…

Computation and Language · Computer Science 2024-02-20 Julien Delile , Srayanta Mukherjee , Anton Van Pamel , Leonid Zhukov

While deep learning has achieved great success in many fields, one common criticism about deep learning is its lack of interpretability. In most cases, the hidden units in a deep neural network do not have a clear semantic meaning or…

Genomics · Quantitative Biology 2019-06-04 Tianle Ma , Aidong Zhang

This comprehensive review aims to provide an overview of the current state of Healthcare Knowledge Graphs (HKGs), including their construction, utilization models, and applications across various healthcare and biomedical research domains.…

Proteins perform much of the work in living organisms, and consequently the development of efficient computational methods for protein representation is essential for advancing large-scale biological research. Most current approaches…

Quantitative Methods · Quantitative Biology 2023-06-09 Francesco Ceccarelli , Lorenzo Giusti , Sean B. Holden , Pietro Liò

Knowledge graph (KG) reasoning is becoming increasingly popular in both academia and industry. Conventional KG reasoning based on symbolic logic is deterministic, with reasoning results being explainable, while modern embedding-based…

Artificial Intelligence · Computer Science 2022-02-16 Wen Zhang , Jiaoyan Chen , Juan Li , Zezhong Xu , Jeff Z. Pan , Huajun Chen

Graph neural networks (GNNs) demonstrate a robust capability for representation learning on graphs with complex structures, showcasing superior performance in various applications. The majority of existing GNNs employ a graph convolution…

Machine Learning · Computer Science 2025-02-19 Jinlu Wang , Jipeng Guo , Yanfeng Sun , Junbin Gao , Shaofan Wang , Yachao Yang , Baocai Yin

Constructing domain-specific knowledge graphs from unstructured text remains challenging due to heterogeneous entity mentions, long-tail relation distributions, and the absence of standardized schemas. We present LEC-KG, a bidirectional…

Computation and Language · Computer Science 2026-03-02 Yikai Zeng , Yingchao Piao , Changhua Pei , Jianhui Li

A Knowledge Graph (KG) is the directed graphical representation of entities and relations in the real world. KG can be applied in diverse Natural Language Processing (NLP) tasks where knowledge is required. The need to scale up and complete…

Computation and Language · Computer Science 2024-04-19 Xincan Feng , Zhi Qu , Yuchang Cheng , Taro Watanabe , Nobuhiro Yugami

Protein representation learning is critical for numerous biological tasks. Recently, large transformer-based protein language models (pLMs) pretrained on large scale protein sequences have demonstrated significant success in sequence-based…

Machine Learning · Computer Science 2025-08-12 Xuefeng Liu , Songhao Jiang , Chih-chan Tien , Jinbo Xu , Rick Stevens

Knowledge Graph (KG) alignment aims at finding equivalent entities and relations (i.e., mappings) between two KGs. The existing approaches utilize either reasoning-based or semantic embedding-based techniques, but few studies explore their…

Computation and Language · Computer Science 2021-08-23 Zhiyuan Qi , Ziheng Zhang , Jiaoyan Chen , Xi Chen , Yefeng Zheng