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Background: Automatic extraction of chemical-disease relations (CDR) from unstructured text is of essential importance for disease treatment and drug development. Meanwhile, biomedical experts have built many highly-structured knowledge…

Computation and Language · Computer Science 2019-12-24 Huiwei Zhou , Chengkun Lang , Zhuang Liu , Shixian Ning , Yingyu Lin , Lei Du

Fine-tuning pre-trained language models (PLMs) has recently shown a potential to improve knowledge graph completion (KGC). However, most PLM-based methods focus solely on encoding textual information, neglecting the long-tailed nature of…

Computation and Language · Computer Science 2025-02-03 Youmin Ko , Hyemin Yang , Taeuk Kim , Hyunjoon Kim

The automatic construction of knowledge graphs (KGs) is an important research area in medicine, with far-reaching applications spanning drug discovery and clinical trial design. These applications hinge on the accurate identification of…

Computation and Language · Computer Science 2025-01-30 Vahan Arsenyan , Spartak Bughdaryan , Fadi Shaya , Kent Small , Davit Shahnazaryan

Retrieval-Augmented Generation (RAG) mitigates hallucinations in Large Language Models (LLMs) by integrating external knowledge. However, conflicts between parametric knowledge and retrieved context pose challenges, particularly when…

Computation and Language · Computer Science 2025-03-21 Baolong Bi , Shenghua Liu , Yiwei Wang , Yilong Xu , Junfeng Fang , Lingrui Mei , Xueqi Cheng

Knowledge Graph Completion (KGC) has been proposed to improve Knowledge Graphs by filling in missing connections via link prediction or relation extraction. One of the main difficulties for KGC is a low resource problem. Previous approaches…

Computation and Language · Computer Science 2023-01-26 Ningyu Zhang , Shumin Deng , Zhanlin Sun , Jiaoayan Chen , Wei Zhang , Huajun Chen

Recently, prompt-tuning has achieved promising results for specific few-shot classification tasks. The core idea of prompt-tuning is to insert text pieces (i.e., templates) into the input and transform a classification task into a masked…

Computation and Language · Computer Science 2023-09-19 Xiang Chen , Ningyu Zhang , Xin Xie , Shumin Deng , Yunzhi Yao , Chuanqi Tan , Fei Huang , Luo Si , Huajun Chen

In many academic settings, medical students start their scientific work already during their studies. Like at our institution, they often work in interdisciplinary teams with more or less experienced (postgraduate) researchers of…

Machine Learning · Statistics 2020-12-08 Andreas D. Meid

This paper aims to enhance the few-shot relation classification especially for sentences that jointly describe multiple relations. Due to the fact that some relations usually keep high co-occurrence in the same context, previous few-shot…

Computation and Language · Computer Science 2020-10-22 Yingyao Wang , Junwei Bao , Guangyi Liu , Youzheng Wu , Xiaodong He , Bowen Zhou , Tiejun Zhao

Clinical text classification requires choosing between specialized fine-tuned models (BERT variants) and general-purpose large language models (LLMs), yet neither dominates across all instances. We introduce Learning to Defer for clinical…

Computation and Language · Computer Science 2026-04-16 Rishik Kondadadi , John E. Ortega

In Natural Language Processing (NLP), Machine Reading Comprehension (MRC) is the task of answering a question based on a given context. To handle questions in the medical domain, modern language models such as BioBERT, SciBERT and even…

Computation and Language · Computer Science 2024-12-16 Saptarshi Sengupta , Connor Heaton , Suhan Cui , Soumalya Sarkar , Prasenjit Mitra

Knowledge Tracing (KT) is a critical technique for modeling student knowledge to support personalized learning. However, most KT systems focus on binary correctness prediction and cannot diagnose the underlying conceptual misunderstandings…

Computation and Language · Computer Science 2026-03-26 Yu-Chen Kang , Yu-Chien Tang , An-Zi Yen

Continually solving new, unsolved tasks is the key to learning diverse behaviors. Through reinforcement learning (RL), we have made massive strides towards solving tasks that have a single goal. However, in the multi-task domain, where an…

Machine Learning · Computer Science 2020-06-18 Yunzhi Zhang , Pieter Abbeel , Lerrel Pinto

In clinical treatment, identifying potential adverse reactions of drugs can help assist doctors in making medication decisions. In response to the problems in previous studies that features are high-dimensional and sparse, independent…

Quantitative Methods · Quantitative Biology 2024-07-30 Yufeng Li , Wenchao Zhao , Bo Dang , Xu Yan , Weimin Wang , Min Gao , Mingxuan Xiao

Electronic Health Records (EHRs) and routine documentation practices play a vital role in patients' daily care, providing a holistic record of health, diagnoses, and treatment. However, complex and verbose EHR narratives overload healthcare…

Computation and Language · Computer Science 2025-02-26 Yanjun Gao , Ruizhe Li , Emma Croxford , John Caskey , Brian W Patterson , Matthew Churpek , Timothy Miller , Dmitriy Dligach , Majid Afshar

Much of biomedical and healthcare data is encoded in discrete, symbolic form such as text and medical codes. There is a wealth of expert-curated biomedical domain knowledge stored in knowledge bases and ontologies, but the lack of reliable…

Artificial Intelligence · Computer Science 2020-06-25 David Chang , Ivana Balazevic , Carl Allen , Daniel Chawla , Cynthia Brandt , Richard Andrew Taylor

In real-world clinical settings, data distributions evolve over time, with a continuous influx of new, limited disease cases. Therefore, class incremental learning is of great significance, i.e., deep learning models are required to learn…

Computer Vision and Pattern Recognition · Computer Science 2024-09-13 Yifei Yao , Hanrong Zhang

Accurate and explainable health event predictions are becoming crucial for healthcare providers to develop care plans for patients. The availability of electronic health records (EHR) has enabled machine learning advances in providing these…

Machine Learning · Computer Science 2021-05-18 Chang Lu , Chandan K. Reddy , Prithwish Chakraborty , Samantha Kleinberg , Yue Ning

This paper proposes a knowledge-enhanced disease diagnosis method based on a prompt learning framework. The method retrieves structured knowledge from external knowledge graphs related to clinical cases, encodes it, and injects it into the…

Computation and Language · Computer Science 2024-09-17 Zhang Zheng

Motivation: Phenotype concept recognition (CR) is a fundamental task in biomedical text mining. However, existing methods either require ontology-specific training, making them struggle to generalize across diverse text styles and evolving…

Computation and Language · Computer Science 2026-04-06 Yicheng Tao , Yuanhao Huang , Yiqun Wang , Xin Luo , Jie Liu

Diabetic retinopathy (DR) is a leading cause of vision loss worldwide, and early diagnosis through automated retinal image analysis can significantly reduce the risk of blindness. This paper presents a robust deep learning framework for…

Computer Vision and Pattern Recognition · Computer Science 2025-07-30 Faisal Ahmed