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This paper introduces a new modeling perspective in the public mental health domain to provide a robust interpretation of the relations between anxiety and depression, and the demographic and temporal factors. This perspective particularly…

Applications · Statistics 2026-01-30 Mustafa Cavus , Przemysław Biecek , Julian Tejada , Fernando Marmolejo-Ramos , Andre Faro

The primary method for identifying mental disorders automatically has traditionally involved using binary classifiers. These classifiers are trained using behavioral data obtained from an interview setup. In this training process, data from…

Neurons and Cognition · Quantitative Biology 2023-08-11 Rohan Kumar Gupta , Rohit Sinha

Predicting whether an individual's depressive symptoms will worsen, remain stable, or improve over the coming weeks can enable earlier and more targeted care, yet prospective within-person trajectory prediction remains largely unaddressed…

Human-Computer Interaction · Computer Science 2026-04-28 Merve Cerit , Andrea Mock , Vryan Almanon Feliciano , Thomas N. Robinson , Byron Reeves , Nilam Ram , Nick Haber

Mental health disorders affect millions worldwide, and healthcare systems are increasingly overwhelmed by the volume of clinical data generated from electronic records, telemedicine platforms, and population-level screening programs. At the…

Artificial Intelligence · Computer Science 2026-05-14 Giuliano Lorenzoni , Paulo Alencar , Donald Cowan

Depression has been the leading cause of mental-health illness worldwide. Major depressive disorder (MDD), is a common mental health disorder that affects both psychologically as well as physically which could lead to loss of lives. Due to…

Computer Vision and Pattern Recognition · Computer Science 2019-09-05 Anupama Ray , Siddharth Kumar , Rutvik Reddy , Prerana Mukherjee , Ritu Garg

Mood disorders such as depression and anxiety often manifest through facial expressions, but existing machine learning algorithms designed to assess these disorders have been hindered by small datasets and limited real-world applicability.…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Xiao Xu , Xizhe Zhang , Yan Zhang

Intensive Longitudinal Data (ILD) is increasingly available to social and behavioral scientists. With this increased availability come new opportunities for modeling and predicting complex biological, behavioral, and physiological…

Methodology · Statistics 2025-01-08 Zachary F. Fisher , Younghoon Kim , Barbara Fredrickson , Vladas Pipiras

Mental health disorders are rising worldwide. However, the availability of trained clinicians has not scaled proportionally, leaving many people without adequate or timely support. To bridge this gap, recent studies have shown the promise…

Computation and Language · Computer Science 2025-08-19 Aishik Mandal , Prottay Kumar Adhikary , Hiba Arnaout , Iryna Gurevych , Tanmoy Chakraborty

In the clinical treatment of mood disorders, the complex behavioral symptoms presented by patients and variability of patient response to particular medication classes can create difficulties in providing fast and reliable treatment when…

Machine Learning · Computer Science 2024-02-13 Bradley T. Baker , Mustafa S. Salman , Zening Fu , Armin Iraji , Elizabeth Osuch , Jeremy Bockholt , Vince D. Calhoun

The relationship between skin diseases and mental illnesses has been extensively studied using cross-sectional epidemiological data. Typically, such data can only measure association (rather than causation) and include only a subset of the…

Applications · Statistics 2024-05-13 Marco Scutari , Delphine Kerob , Samir Salah

Background: Clinical trials are designed to prove the efficacy of an intervention by means of model-based approaches involving parametric hypothesis testing. Issues arise when no effect is observed in the study population. Indeed, an effect…

Every day, users generate digital traces (e.g., social media posts, chats, and online interactions) that are inherently timestamped and may reflect aspects of their mental state. These traces can be organized into temporal trajectories that…

Artificial Intelligence · Computer Science 2026-05-15 Loris Belcastro , Francesco Gervino , Fabrizio Marozzo , Domenico Talia , Paolo Trunfio

Mental disorders are among the foremost contributors to the global healthcare challenge. Research indicates that timely diagnosis and intervention are vital in treating various mental disorders. However, the early somatization symptoms of…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Yichun Li , Shuanglin Li , Syed Mohsen Naqvi

The therapeutic working alliance is a critical predictor of psychotherapy success. Traditionally, working alliance assessment relies on questionnaires completed by both therapists and patients. In this paper, we present COMPASS, a novel…

Computation and Language · Computer Science 2025-08-12 Baihan Lin , Djallel Bouneffouf , Yulia Landa , Rachel Jespersen , Cheryl Corcoran , Guillermo Cecchi

A fundamental approach in neuroscience research is to test hypotheses based on neuropsychological and behavioral measures, i.e., whether certain factors (e.g., related to life events) are associated with an outcome (e.g., depression). In…

Machine Learning · Computer Science 2022-08-01 Magdalini Paschali , Qingyu Zhao , Ehsan Adeli , Kilian M. Pohl

Hematotoxicity, drug-induced damage to the blood-forming system, is a frequent side effect of cytotoxic chemotherapy and poses a significant challenge in clinical practice due to its high inter-patient variability and limited…

Machine Learning · Computer Science 2025-05-28 Marie Steinacker , Yuri Kheifetz , Markus Scholz

Parkinsons disease, PD, is a chronic condition that affects motor skills and includes symptoms like tremors and rigidity. The current diagnostic procedure uses patient assessments to evaluate symptoms and sometimes a magnetic resonance…

Image and Video Processing · Electrical Eng. & Systems 2022-01-14 Sabrina Zhu

We address the problem of causal discovery from data, making use of the recently proposed causal modeling framework of modular structural causal models (mSCM) to handle cycles, latent confounders and non-linearities. We introduce…

Machine Learning · Statistics 2022-08-31 Patrick Forré , Joris M. Mooij

A wide variety of methods have been developed for identifying depression, but they focus primarily on measuring the degree to which individuals are suffering from depression currently. In this work we explore the possibility of predicting…

Machine Learning · Computer Science 2022-03-22 Guansong Pang , Ngoc Thien Anh Pham , Emma Baker , Rebecca Bentley , Anton van den Hengel

We propose a pipeline for gaining insights into complex diseases by training LLMs on challenging social media text data classification tasks, obtaining explanations for the classification outputs, and performing qualitative and quantitative…

Computation and Language · Computer Science 2024-12-17 Kexin Chen , Noelle Lim , Claire Lee , Michael Guerzhoy