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The advancement of Large Language Models (LLMs), including GPT-4, provides exciting new opportunities for generative design. We investigate the application of this tool across the entire design and manufacturing workflow. Specifically, we…

Natural language processing (NLP) has significantly influenced scientific domains beyond human language, including protein engineering, where pre-trained protein language models (PLMs) have demonstrated remarkable success. However,…

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Generative protein language models are a natural way to design new proteins with desired functions. However, current models are either difficult to direct to produce a protein from a specific family of interest, or must be trained on a…

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A plethora of protein language models have been released in recent years. Yet comparatively little work has addressed how to best sample from them to optimize desired biological properties. We fill this gap by proposing a flexible,…

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Since the inception of the Transformer architecture in 2017, Large Language Models (LLMs) such as GPT and BERT have evolved significantly, impacting various industries with their advanced capabilities in language understanding and…

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Transformer-based pre-trained models have gained much advance in recent years, becoming one of the most important backbones in natural language processing. Recent work shows that the attention mechanism inside Transformer may not be…

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Natural Language Processing (NLP) helps empower intelligent machines by enhancing a better understanding of the human language for linguistic-based human-computer communication. Recent developments in computational power and the advent of…

Computation and Language · Computer Science 2021-03-02 Amirsina Torfi , Rouzbeh A. Shirvani , Yaser Keneshloo , Nader Tavaf , Edward A. Fox

The design of protein sequences with desired functionalities is a fundamental task in protein engineering. Deep generative methods, such as autoregressive models and diffusion models, have greatly accelerated the discovery of novel protein…

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Graph Transformers (GTs) have demonstrated a strong capability in modeling graph structures by addressing the intrinsic limitations of graph neural networks (GNNs), such as over-smoothing and over-squashing. Recent studies have proposed…

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Foundation models have revolutionized natural language processing and artificial intelligence, significantly enhancing how machines comprehend and generate human languages. Inspired by the success of these foundation models, researchers…

Since the Transformer architecture emerged, language model development has grown, driven by their promising potential. Releasing these models into production requires properly understanding their behavior, particularly in sensitive domains…

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In the last half-decade, the field of natural language processing (NLP) has undergone two major transitions: the switch to neural networks as the primary modeling paradigm and the homogenization of the training regime (pre-train, then…

Computation and Language · Computer Science 2021-10-19 Artur Kulmizev , Joakim Nivre

Recent advances in Pretrained Language Models (PLMs) and Large Language Models (LLMs) have demonstrated transformative capabilities across diverse domains. The field of patent analysis and innovation is not an exception, where natural…

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In this work we systematically review the recent advancements in software engineering with language models, covering 70+ models, 40+ evaluation tasks, 180+ datasets, and 900 related works. Unlike previous works, we integrate software…

Computation and Language · Computer Science 2024-06-27 Ziyin Zhang , Chaoyu Chen , Bingchang Liu , Cong Liao , Zi Gong , Hang Yu , Jianguo Li , Rui Wang

Language models (LMs) built upon deep neural networks (DNNs) have recently demonstrated breakthrough effectiveness in software engineering tasks such as code generation, completion, and repair. This has paved the way for the emergence of…

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Transformer, originally devised for natural language processing, has also attested significant success in computer vision. Thanks to its super expressive power, researchers are investigating ways to deploy transformers to reinforcement…

Machine Learning · Computer Science 2023-01-24 Shengchao Hu , Li Shen , Ya Zhang , Yixin Chen , Dacheng Tao

Transformers have had a significant impact on natural language processing and have recently demonstrated their potential in computer vision. They have shown promising results over convolution neural networks in fundamental computer vision…

Computer Vision and Pattern Recognition · Computer Science 2023-11-14 Rojina Kashefi , Leili Barekatain , Mohammad Sabokrou , Fatemeh Aghaeipoor

State-of-the-art deep-learning-based approaches to Natural Language Processing (NLP) are credited with various capabilities that involve reasoning with natural language texts. In this paper we carry out a large-scale empirical study…

Computation and Language · Computer Science 2022-11-11 Viktor Schlegel , Kamen V. Pavlov , Ian Pratt-Hartmann

Transformer models have revolutionized natural language processing with their unparalleled ability to grasp complex contextual relationships. However, the vast number of parameters in these models has raised concerns regarding computational…

Machine Learning · Computer Science 2023-10-10 Sia Gholami , Marwan Omar

Large-scale Protein Language Models (PLMs) have improved performance in protein prediction tasks, ranging from 3D structure prediction to various function predictions. In particular, AlphaFold, a ground-breaking AI system, could potentially…

Quantitative Methods · Quantitative Biology 2022-10-18 Mingyang Hu , Fajie Yuan , Kevin K. Yang , Fusong Ju , Jin Su , Hui Wang , Fei Yang , Qiuyang Ding
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