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Ensuring transparency and trust in AI-driven public health and biomedical sciences systems requires more than accurate predictions-it demands explanations that are clear, contextual, and socially accountable. While explainable AI (XAI) has…

Artificial Intelligence · Computer Science 2025-07-30 Bahar İlgen , Akshat Dubey , Georges Hattab

The lack of explainability of a decision from an Artificial Intelligence (AI) based "black box" system/model, despite its superiority in many real-world applications, is a key stumbling block for adopting AI in many high stakes applications…

Artificial Intelligence · Computer Science 2021-01-26 Sheikh Rabiul Islam , William Eberle , Sheikh Khaled Ghafoor , Mohiuddin Ahmed

In recent years, AI systems in the medical domain have advanced significantly. However, despite outperforming humans, they are rarely used in practice since it is often not clear how they make their decisions. Optimal explanation and…

Human-Computer Interaction · Computer Science 2026-05-06 Julia Wagner , Tim Schlippe

Explainable artificial intelligence (XAI) has become increasingly important in biomedical image analysis to promote transparency, trust, and clinical adoption of DL models. While several surveys have reviewed XAI techniques, they often lack…

Computer Vision and Pattern Recognition · Computer Science 2025-07-11 Getamesay Haile Dagnaw , Yanming Zhu , Muhammad Hassan Maqsood , Wencheng Yang , Xingshuai Dong , Xuefei Yin , Alan Wee-Chung Liew

Uncertainty is a fundamental challenge in medical practice, but current medical AI systems fail to explicitly quantify or communicate uncertainty in a way that aligns with clinical reasoning. Existing XAI works focus on interpreting model…

Artificial Intelligence · Computer Science 2025-09-24 Xiuyi Fan

Explainable AI has become a common term in the literature, scrutinized by computer scientists and statisticians and highlighted by psychological or philosophical researchers. One major effort many researchers tackle is constructing general…

Artificial Intelligence · Computer Science 2025-09-12 Carina Newen , Daniel Bodemer , Sonja Glantz , Emmanuel Müller , Magdalena Wischnewski , Lenka Schnaubert

Despite the growing interest in Explainable Artificial Intelligence (XAI), explainability is rarely considered during hyperparameter tuning or neural architecture optimization, where the focus remains primarily on minimizing predictive…

Machine Learning · Computer Science 2025-05-26 Alexander Hinterleitner , Thomas Bartz-Beielstein

Artificial intelligence models encounter significant challenges due to their black-box nature, particularly in safety-critical domains such as healthcare, finance, and autonomous vehicles. Explainable Artificial Intelligence (XAI) addresses…

Artificial Intelligence · Computer Science 2025-03-14 Melkamu Mersha , Khang Lam , Joseph Wood , Ali AlShami , Jugal Kalita

Accurate and interpretable survival analysis remains a core challenge in oncology. With growing multimodal data and the clinical need for transparent models to support validation and trust, this challenge increases in complexity. We propose…

Artificial Intelligence · Computer Science 2025-09-29 Mafalda Malafaia , Peter A. N. Bosman , Coen Rasch , Tanja Alderliesten

The significant features identified in a representative subset of the dataset during the learning process of an artificial intelligence model are referred to as a 'global' explanation. 3D global explanations are crucial in neuroimaging,…

Widespread use of artificial intelligence (AI) algorithms and machine learning (ML) models on the one hand and a number of crucial issues pertaining to them warrant the need for explainable artificial intelligence (XAI). A key…

Artificial Intelligence · Computer Science 2023-12-13 Jinqiang Yu , Graham Farr , Alexey Ignatiev , Peter J. Stuckey

Explainable artificial intelligence (XAI) plays an indispensable role in demystifying the decision-making processes of AI, especially within the healthcare industry. Clinicians rely heavily on detailed reasoning when making a diagnosis,…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Anna Stubbin , Thompson Chyrikov , Jim Zhao , Christina Chajo

Visual recognition models have achieved unprecedented success in various tasks. While researchers aim to understand the underlying mechanisms of these models, the growing demand for deployment in safety-critical areas like autonomous…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Qiyang Wan , Chengzhi Gao , Ruiping Wang , Xilin Chen

Lack of transparency in AI systems poses challenges in critical real-life applications. It is important to be able to explain the decisions of an AI system to ensure trust on the system. Explainable AI (XAI) algorithms play a vital role in…

Machine Learning · Computer Science 2026-05-15 Sayantani Ghosh , Amit Kumar Das , Amlan Chakrabarti

Explainable AI (XAI) has revolutionized the field of deep learning by empowering users to have more trust in neural network models. The field of XAI allows users to probe the inner workings of these algorithms to elucidate their…

Computer Vision and Pattern Recognition · Computer Science 2024-06-13 Prithwijit Chowdhury , Mohit Prabhushankar , Ghassan AlRegib , Mohamed Deriche

A main drawback of eXplainable Artificial Intelligence (XAI) approaches is the feature independence assumption, hindering the study of potential variable dependencies. This leads to approximating black box behaviors by analyzing the effects…

Artificial Intelligence · Computer Science 2024-10-16 Martina Cinquini , Riccardo Guidotti

Explainable AI (XAI) is critical for building trust in complex machine learning models, yet mainstream attribution methods often provide an incomplete, static picture of a model's final state. By collapsing a feature's role into a single…

Machine Learning · Computer Science 2025-11-03 Hamed Najafi , Dongsheng Luo , Jason Liu

Explainable AI (XAI) methods focus on explaining what a neural network has learned - in other words, identifying the features that are the most influential to the prediction. In this paper, we call them "distinguishing features". However,…

Computer Vision and Pattern Recognition · Computer Science 2021-04-19 Kaili Wang , Jose Oramas , Tinne Tuytelaars

This paper compares model-agnostic and model-specific approaches to explainable AI (XAI) in deep learning image classification. I examine how LIME and SHAP (model-agnostic methods) differ from Grad-CAM and Guided Backpropagation…

Artificial Intelligence · Computer Science 2025-04-08 Keerthi Devireddy

Artificial Intelligence (AI) has become essential for analyzing complex data and solving highly-challenging tasks. It is being applied across numerous disciplines beyond computer science, including Food Engineering, where there is a growing…