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On the medical images, many of the tissues/lesions may be ambiguous. That is why the medical segmentation is typically annotated by a group of clinical experts to mitigate the personal bias. However, this clinical routine also brings new…

Image and Video Processing · Electrical Eng. & Systems 2022-08-08 Junde Wu , Huihui Fang , Hoayi Xiong , Lixin Duan , Mingkui Tan , Weihua Yang , Huiying Liu , Yanwu Xu

Denoising diffusion models, a class of generative models, have garnered immense interest lately in various deep-learning problems. A diffusion probabilistic model defines a forward diffusion stage where the input data is gradually perturbed…

Image and Video Processing · Electrical Eng. & Systems 2023-06-06 Amirhossein Kazerouni , Ehsan Khodapanah Aghdam , Moein Heidari , Reza Azad , Mohsen Fayyaz , Ilker Hacihaliloglu , Dorit Merhof

Obtaining large-scale medical data, annotated or unannotated, is challenging due to stringent privacy regulations and data protection policies. In addition, annotating medical images requires that domain experts manually delineate…

Computer Vision and Pattern Recognition · Computer Science 2025-05-16 Tushar Kataria , Shireen Y. Elhabian

Objective: Accurate probability estimates are essential for the safe deployment of medical image segmentation models in clinical decision-making. However, modern deep segmentation networks are often poorly calibrated, a problem exacerbated…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Meritxell Riera-Marín , Javier García López , Júlia Rodríguez-Comas , Miguel A. González Ballester , Adrian Galdran

In recent years, Denoising Diffusion Models have demonstrated remarkable success in generating semantically valuable pixel-wise representations for image generative modeling. In this study, we propose a novel end-to-end framework, called…

Image and Video Processing · Electrical Eng. & Systems 2023-03-21 Zhaohu Xing , Liang Wan , Huazhu Fu , Guang Yang , Lei Zhu

Diffusion Probabilistic Methods are employed for state-of-the-art image generation. In this work, we present a method for extending such models for performing image segmentation. The method learns end-to-end, without relying on a…

Computer Vision and Pattern Recognition · Computer Science 2022-09-08 Tomer Amit , Tal Shaharbany , Eliya Nachmani , Lior Wolf

Denoising Diffusion Probabilistic models have become increasingly popular due to their ability to offer probabilistic modeling and generate diverse outputs. This versatility inspired their adaptation for image segmentation, where multiple…

Automated semantic segmentation of cell nuclei in microscopic images is crucial for disease diagnosis and tissue microenvironment analysis. Nonetheless, this task presents challenges due to the complexity and heterogeneity of cells. While…

Image and Video Processing · Electrical Eng. & Systems 2023-08-10 Zhuchen Shao , Sourya Sengupta , Hua Li , Mark A. Anastasio

The ability to quickly annotate medical imaging data plays a critical role in training deep learning frameworks for segmentation. Doing so for image volumes or video sequences is even more pressing as annotating these is particularly…

Computer Vision and Pattern Recognition · Computer Science 2021-07-20 Laurent Lejeune , Raphael Sznitman

Anomaly detection in medical imaging plays a crucial role in identifying pathological regions across various imaging modalities, such as brain MRI, liver CT, and carotid ultrasound (US). However, training fully supervised segmentation…

Image and Video Processing · Electrical Eng. & Systems 2025-07-29 Yuan Bi , Lucie Huang , Ricarda Clarenbach , Reza Ghotbi , Angelos Karlas , Nassir Navab , Zhongliang Jiang

Deep learning algorithms have become the golden standard for segmentation of medical imaging data. In most works, the variability and heterogeneity of real clinical data is acknowledged to still be a problem. One way to automatically…

Image and Video Processing · Electrical Eng. & Systems 2022-02-25 Arkadiy Dushatskiy , Gerry Lowe , Peter A. N. Bosman , Tanja Alderliesten

Deformable image registration aims to precisely align medical images from different modalities or times. Traditional deep learning methods, while effective, often lack interpretability, real-time observability and adjustment capacity during…

Computer Vision and Pattern Recognition · Computer Science 2024-10-08 Yongtai Zhuo , Yiqing Shen

Aside from offering state-of-the-art performance in medical image generation, denoising diffusion probabilistic models (DPM) can also serve as a representation learner to capture semantic information and potentially be used as an image…

Image and Video Processing · Electrical Eng. & Systems 2024-07-09 Chun-Mei Feng

Manual annotation of medical images is highly subjective, leading to inevitable and huge annotation biases. Deep learning models may surpass human performance on a variety of tasks, but they may also mimic or amplify these biases. Although…

Computer Vision and Pattern Recognition · Computer Science 2022-03-23 Zehui Liao , Shishuai Hu , Yutong Xie , Yong Xia

Large annotated datasets are crucial for the success of deep neural networks, but labeling data can be prohibitively expensive in domains such as medical imaging. This work tackles the subset selection problem: selecting a small set of the…

Machine Learning · Computer Science 2025-09-29 Noga Bar , Raja Giryes

Open-vocabulary semantic segmentation (OVSS) aims to segment objects from arbitrary text categories without requiring densely annotated datasets. Although contrastive learning based models enable zero-shot segmentation, they often lose fine…

Computer Vision and Pattern Recognition · Computer Science 2026-04-30 Huy Che , Vinh-Tiep Nguyen

There has recently been great progress in automatic segmentation of medical images with deep learning algorithms. In most works observer variation is acknowledged to be a problem as it makes training data heterogeneous but so far no…

Computer Vision and Pattern Recognition · Computer Science 2020-01-24 Arkadiy Dushatskiy , Adriënne M. Mendrik , Peter A. N. Bosman , Tanja Alderliesten

Multi-rater annotations commonly occur when medical images are independently annotated by multiple experts (raters). In this paper, we tackle two challenges arisen in multi-rater annotations for medical image segmentation (called ambiguous…

Computer Vision and Pattern Recognition · Computer Science 2024-08-26 Jinhong Wang , Yi Cheng , Jintai Chen , Hongxia Xu , Danny Chen , Jian Wu

In spite of recent progress, image diffusion models still produce artifacts. A common solution is to leverage the feedback provided by quality assessment systems or human annotators to optimize the model, where images are generally rated in…

Computer Vision and Pattern Recognition · Computer Science 2025-03-12 Yiyang Wang , Xi Chen , Xiaogang Xu , Sihui Ji , Yu Liu , Yujun Shen , Hengshuang Zhao

Medical image segmentation often involves inherent uncertainty due to variations in expert annotations. Capturing this uncertainty is an important goal and previous works have used various generative image models for the purpose of…

Computer Vision and Pattern Recognition · Computer Science 2025-08-19 Jakob Lønborg Christensen , Morten Rieger Hannemose , Anders Bjorholm Dahl , Vedrana Andersen Dahl