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Protein language models have revolutionized structure prediction, but their nonlinear nature obscures how sequence representations inform structure prediction. While sparse autoencoders (SAEs) offer a path to interpretability here by…

Biomolecules · Quantitative Biology 2025-03-13 Nithin Parsan , David J. Yang , John J. Yang

This study explores the application of Convolutional Autoencoders (CAEs) for analyzing and reconstructing Scanning Tunneling Microscopy (STM) images of various crystalline lattice structures. We developed two distinct CAE architectures to…

Numerical Analysis · Mathematics 2025-01-24 Peter Binev , Joshua Moorehead , Ayush Parambath , Luke Parrella , Rori Pumphrey , Miruna Savu

The growing volume of high-resolution Whole Slide Images in digital histopathology poses significant storage, transmission, and computational efficiency challenges. Standard compression methods, such as JPEG, reduce file sizes but often…

Image and Video Processing · Electrical Eng. & Systems 2025-03-17 Srikar Yellapragada , Alexandros Graikos , Kostas Triaridis , Zilinghan Li , Tarak Nath Nandi , Ravi K Madduri , Prateek Prasanna , Joel Saltz , Dimitris Samaras

A common goal of mechanistic interpretability is to decompose the activations of neural networks into features: interpretable properties of the input computed by the model. Sparse autoencoders (SAEs) are a popular method for finding these…

Machine Learning · Computer Science 2025-02-10 Patrick Leask , Bart Bussmann , Michael Pearce , Joseph Bloom , Curt Tigges , Noura Al Moubayed , Lee Sharkey , Neel Nanda

Large Language Models (LLMs) have transformed natural language processing, yet their internal mechanisms remain largely opaque. Recently, mechanistic interpretability has attracted significant attention from the research community as a…

Machine Learning · Computer Science 2025-09-24 Dong Shu , Xuansheng Wu , Haiyan Zhao , Daking Rai , Ziyu Yao , Ninghao Liu , Mengnan Du

Sparse autoencoders (SAEs) aim to disentangle model activations into monosemantic, human-interpretable features. In practice, learned features are often redundant and vary across training runs and sparsity levels, which makes…

Machine Learning · Computer Science 2026-01-01 Cristina P. Martin-Linares , Jonathan P. Ling

Autoencoders have been used for finding interpretable and disentangled features underlying neural network representations in both image and text domains. While the efficacy and pitfalls of such methods are well-studied in vision, there is a…

Machine Learning · Computer Science 2025-02-06 Abhinav Menon , Manish Shrivastava , David Krueger , Ekdeep Singh Lubana

In this paper we propose Structuring AutoEncoders (SAE). SAEs are neural networks which learn a low dimensional representation of data which are additionally enriched with a desired structure in this low dimensional space. While traditional…

Machine Learning · Computer Science 2019-08-20 Marco Rudolph , Bastian Wandt , Bodo Rosenhahn

Sparse Autoencoders (SAEs) have emerged as a promising approach for interpreting neural network representations by learning sparse, human-interpretable features from dense activations. We investigate whether incorporating variational…

Machine Learning · Computer Science 2025-10-03 Zachary Baker , Yuxiao Li

Sparse autoencoders (SAEs) are widely used to extract sparse, interpretable latents from transformer activations. We test whether commonly used SAE quality metrics and automatic explanation pipelines can distinguish trained transformers…

Machine Learning · Computer Science 2026-01-28 Thomas Heap , Tim Lawson , Lucy Farnik , Laurence Aitchison

Sparse autoencoders (SAEs) have emerged as a powerful technique for decomposing language model representations into interpretable features. Current interpretation methods infer feature semantics from activation patterns, but overlook that…

Machine Learning · Computer Science 2026-02-02 Yiting Liu , Zhi-Hong Deng

Standard Sparse Autoencoders (SAEs) excel at discovering a dictionary of a model's learned features, offering a powerful observational lens. However, the ambiguous and ungrounded nature of these features makes them unreliable instruments…

Machine Learning · Computer Science 2025-09-29 Jianrong Ding , Muxi Chen , Chenchen Zhao , Qiang Xu

Sparse autoencoders (SAEs) extract millions of interpretable features from a language model, but flat feature inventories aren't very useful on their own. Domain concepts get mixed with generic and weakly grounded features, while related…

Artificial Intelligence · Computer Science 2026-04-29 John Winnicki , Abeynaya Gnanasekaran , Eric Darve

Sparse autoencoders (SAEs) have emerged as a powerful tool for interpreting large language models (LLMs) by decomposing token activations into combinations of human-understandable features. While SAEs provide crucial insights into LLM…

Machine Learning · Computer Science 2025-11-11 Zhen Xu , Zhen Tan , Song Wang , Kaidi Xu , Tianlong Chen

The rapid advancements in transformer-based language models have revolutionized natural language processing, yet understanding the internal mechanisms of these models remains a significant challenge. This paper explores the application of…

Machine Learning · Computer Science 2025-02-14 Edith Natalia Villegas Garcia , Alessio Ansuini

Sparse autoencoders (SAEs) have emerged as a powerful tool for interpreting language model activations by decomposing them into sparse, interpretable features. A popular approach is the TopK SAE, that uses a fixed number of the most active…

Machine Learning · Computer Science 2024-12-10 Bart Bussmann , Patrick Leask , Neel Nanda

We present SAE-BrainMap, a novel framework that directly aligns deep learning visual model representations with voxel-level fMRI responses using sparse autoencoders (SAEs). First, we train layer-wise SAEs on model activations and compute…

Neurons and Cognition · Quantitative Biology 2025-06-16 Ziming Mao , Jia Xu , Zeqi Zheng , Haofang Zheng , Dabing Sheng , Yaochu Jin , Guoyuan Yang

Understanding the internal representations of large language models (LLMs) remains a central challenge for interpretability research. Sparse autoencoders (SAEs) offer a promising solution by decomposing activations into interpretable…

Machine Learning · Computer Science 2025-10-10 Yifei Yao , Mengnan Du

Sparse Autoencoders (SAEs) have recently emerged as powerful tools for interpreting and steering the internal representations of large language models (LLMs). However, conventional approaches to analyzing SAEs typically rely solely on…

Machine Learning · Computer Science 2025-09-24 Dong Shu , Xuansheng Wu , Haiyan Zhao , Mengnan Du , Ninghao Liu

As black box models and pretrained models gain traction in time series applications, understanding and explaining their predictions becomes increasingly vital, especially in high-stakes domains where interpretability and trust are…

Machine Learning · Computer Science 2026-01-16 Khalid Oublal , Quentin Bouniot , Qi Gan , Stephan Clémençon , Zeynep Akata
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