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Backpropagation is the core learning mechanism underlying deep learning. However, whether and how this algorithm is implemented in the brain remains highly debated. In particular, while forward activations of pretrained models reliably map…

Encoding models provide a powerful framework for linking continuous stimulus features to neural activity; however, traditional voxelwise approaches are limited by measurement noise, inter-subject variability, and redundancy arising from…

Computation and Language · Computer Science 2026-04-29 Kamya Hari , Taha Binhuraib , Jin Li , Cory Shain , Anna A. Ivanova

Decoding visual signals holds the tantalizing potential to unravel the complexities of cognition and perception. While recent studies have focused on reconstructing visual stimuli from neural recordings to bridge brain activity with visual…

Computational Engineering, Finance, and Science · Computer Science 2025-09-23 Zixiang Yin , Jiarui Li , Zhengming Ding

Neurons in the brain represent external stimuli via neural codes. These codes often arise from stereotyped stimulus-response maps, associating to each neuron a convex receptive field. An important problem confronted by the brain is to infer…

Neurons and Cognition · Quantitative Biology 2015-02-25 Carina Curto , Vladimir Itskov , Alan Veliz-Cuba , Nora Youngs

Brain encoding and decoding aims to understand the relationship between external stimuli and brain activities, and is a fundamental problem in neuroscience. In this article, we study latent embedding alignment for brain encoding and…

Methodology · Statistics 2026-03-24 Shuoxun Xu , Zhanhao Yan , Lexin Li

Dreaming is generally thought to be generated by spontaneous brain activity during sleep with patterns common to waking experience. This view is supported by a recent study demonstrating that dreamed objects can be predicted from brain…

Neurons and Cognition · Quantitative Biology 2017-01-24 Tomoyasu Horikawa , Yukiyasu Kamitani

Support vector machine (SVM) based multivariate pattern analysis (MVPA) has delivered promising performance in decoding specific task states based on functional magnetic resonance imaging (fMRI) of the human brain. Conventionally, the…

Existing approaches to modeling associations between visual stimuli and brain responses are facing difficulties in handling between-subject variance and model generalization. Inspired by the recent progress in modeling speech-brain…

Computer Vision and Pattern Recognition · Computer Science 2023-11-23 Yiqian Yang , Zhengqiao Zhao , Qian Wang , Yan Yang , Jingdong Chen

Despite significant strides in visual quality assessment, the neural mechanisms underlying visual quality perception remain insufficiently explored. This study employed fMRI to examine brain activity during image quality assessment and…

Multimedia · Computer Science 2024-04-30 Yiming Zhang , Ying Hu , Xiongkuo Min , Yan Zhou , Guangtao Zhai

Creativity, a process that generates novel and meaningful ideas, involves increased association between task-positive (control) and task-negative (default) networks in the human brain. Inspired by this seminal finding, in this study we…

Artificial Intelligence · Computer Science 2020-04-24 Payel Das , Brian Quanz , Pin-Yu Chen , Jae-wook Ahn , Dhruv Shah

Deciphering brain function through non-invasive recordings requires synthesizing complementary high-frequency electromagnetic (EEG/MEG) and low-frequency metabolic (fMRI) signals. However, despite their shared neural origins, extreme…

Neurons and Cognition · Quantitative Biology 2026-02-26 Changli Tang , Shurui Li , Junliang Wang , Qinfan Xiao , Zhonghao Zhai , Lei Bai , Yu Qiao , Bowen Zhou , Wen Wu , Yuanning Li , Chao Zhang

Brain decoding, aiming to identify the brain states using neural activity, is important for cognitive neuroscience and neural engineering. However, existing machine learning methods for fMRI-based brain decoding either suffer from low…

Neurons and Cognition · Quantitative Biology 2022-10-13 Ziyuan Ye , Youzhi Qu , Zhichao Liang , Mo Wang , Quanying Liu

Due to the lack of paired samples and the low signal-to-noise ratio of functional MRI (fMRI) signals, reconstructing perceived natural images or decoding their semantic contents from fMRI data are challenging tasks. In this work, we…

Computer Vision and Pattern Recognition · Computer Science 2023-05-16 Yulong Liu , Yongqiang Ma , Wei Zhou , Guibo Zhu , Nanning Zheng

Psychovisual models suggest human vision decouples low-level feature extraction from higher cognition by first forming intermediate abstractions. In contrast, deep learning-based vision models routinely extract and aggregate features using…

Computer Vision and Pattern Recognition · Computer Science 2026-05-29 Wendi Ma , Aryaman Sharma , Wei Dai , Shekhar S. Chandra

We study the intriguing connection between visual data, deep networks, and the brain. Our method creates a universal channel alignment by using brain voxel fMRI response prediction as the training objective. We discover that deep networks,…

Computer Vision and Pattern Recognition · Computer Science 2026-04-22 Huzheng Yang , James Gee , Jianbo Shi

Early detection is crucial for timely intervention aimed at preventing and slowing the progression of neurocognitive disorder (NCD), a common and significant health problem among the aging population. Recent evidence has suggested that…

Computation and Language · Computer Science 2025-06-11 Yuejiao Wang , Xianmin Gong , Xixin Wu , Patrick Wong , Hoi-lam Helene Fung , Man Wai Mak , Helen Meng

Functional Magnetic Resonance Imaging (fMRI) maps cerebral activation in response to stimuli but this activation is often difficult to detect, especially in low-signal contexts and single-subject studies. Accurate activation detection can…

Applications · Statistics 2023-10-26 Wei-Chen Chen , Ranjan Maitra

Task functional magnetic resonance imaging (fMRI) is a type of neuroimaging data used to identify areas of the brain that activate during specific tasks or stimuli. These data are conventionally modeled using a massive univariate approach…

Methodology · Statistics 2022-11-04 Daniel A. Spencer , David Bolin , Amanda F. Mejia

Electroencephalography (EEG) foundation models hold significant promise for universal Brain-Computer Interfaces (BCIs). However, existing approaches often rely on end-to-end fine-tuning and exhibit limited efficacy under frozen-probing…

Machine Learning · Computer Science 2026-03-20 Jiquan Wang , Sha Zhao , Yangxuan Zhou , Yiming Kang , Shijian Li , Gang Pan

Converging evidence suggests that the mammalian ventral visual pathway encodes increasingly complex stimulus features in downstream areas. Using deep convolutional neural networks, we can now quantitatively demonstrate that there is indeed…

Neurons and Cognition · Quantitative Biology 2017-03-13 Umut Güçlü , Marcel A. J. van Gerven