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This study presents a three-dimensional transient computational fluid dynamics simulation of droplet generation in a flow-focusing microfluidic device using the Coupled Level Set and Volume of Fluid method for interface capturing. We…

Fluid Dynamics · Physics 2025-07-17 Manohar Jammula , Somasekhara Goud Sontti

This study investigates the hydrodynamics of droplet formation in a T-shaped cylindrical microfluidic device using micro-PIV experiments and CFD simulations. Devices of 150 micro-m internal diameter were fabricated from PDMS via a…

Fluid Dynamics · Physics 2026-03-04 Pratibha Dogra , Ram Prakash Bharti , Gaurav Sharma

We have developed a coupled level set and volume of fluid-based computational fluid dynamics model to analyze the droplet formation mechanism in a square flow-focusing microchannel. We demonstrate a flexible manipulation of droplet…

Fluid Dynamics · Physics 2025-10-09 Somasekhara Goud Sontti , Arnab Atta

In this article, we have developed a computational model to determine the droplet formation regime and its transition in a square microfluidic flow-focusing device that eventually dictate the droplet shape, size, and its formation…

Fluid Dynamics · Physics 2025-10-28 Somasekhara Goud Sontti , Arnab Atta

Shear-induced droplet formation is important in many industrial applications, primarily focusing on droplet sizes and pinch-off frequency. We propose a one-dimensional mathematical model that describes the effect of shear forces on the…

Fluid Dynamics · Physics 2024-05-30 Darsh Nathawani , Matthew Knepley

Significant progress has been made to increase access to droplet microfluidics for labs with limited microfluidics expertise or fabrication equipment. In particular, using off-the-shelf systems has been a valuable approach. However, the…

Precise control of multiphase microfluidic flows underpins applications ranging from chemical processing to biomedical diagnostics. We investigate the response of a liquid--liquid coflow in a rectangular microchannel to an externally…

Fluid Dynamics · Physics 2026-04-08 D. Ghosh , S. Z. Hoque , T. Sujith , N. S. Satpathi , L. Malik , A. K. Sen

Droplet-based microfluidics systems have become widely used in recent years thanks to their advantages, varying from the possibility of handling small fluid volumes to directly synthesizing and encapsulating various living forms for…

In this study, two phase gas-shear-thinning liquid flow in a square microchannel is numerically investigated using the coupled level set and volume of fluid (CLSVOF) methods. A systematic investigation is carried out to explore the…

The generation of microdroplets via segmentation in microfluidic devices is of interest in many applications, from biochemical to pharmaceutical. This technique permits indeed much higher control on the droplet size, uniformity and…

Fluid Dynamics · Physics 2026-01-15 Alessio Innocenti , Andrea Poggi , Simone Camarri , Maria Vittoria Salvetti

The design of strategies to generate efficient mixing is crucial for a variety of applications, particularly digital microfluidic devices that use small "discrete" fluid volumes (droplets) as fluid carriers and microreactors. In recent…

Chaotic Dynamics · Physics 2008-09-03 R. Chabreyrie , D. Vainchtein , C. Chandre , P. Singh , N. Aubry

In microfluidic systems, droplets undergo intricate deformations as they traverse flow-focusing junctions, posing a challenging task for accurate measurement, especially during short transit times. This study investigates the physical…

The present study deals with the numerical as well as asymptotic analysis of the electrohydrodynamic interaction between two deformable droplets in a confined shear flow. Considering both the phases as leaky dielectric, we have performed…

Fluid Dynamics · Physics 2019-03-27 Somnath Santra , Diptendu Sen , Sayan Das , Suman Chakraborty

We employ a multi-phase smoothed particle hydrodynamics (SPH) method to study droplet dynamics in shear flow. With an extensive range of Reynolds number, capillary number, wall confinement, and density/viscosity ratio between the droplet…

Fluid Dynamics · Physics 2023-07-07 Kuiliang Wang , Hong Liang , Chong Zhao , Xin Bian

The hydrodynamics of droplets is significant in wide-ranging applications involving immiscible fluids and emulsions in food and pharmaceutical. The control and manipulation of droplets are primarily a function of flow governing and…

Fluid Dynamics · Physics 2022-01-19 Akepogu Venkateshwarlu , Ram Prakash Bharti

A three-dimensional, volume-of-fluid (VOF) based CFD model is presented to investigate droplet formation in a microfluidic T-junction. Genesis of Newtonian droplets in non-Newtonian liquid is numerically studied and characterized in three…

Fluid Dynamics · Physics 2025-10-09 Somasekhara Goud Sontti , Arnab Atta

Droplets confined in a microfluidic channel often exhibit intriguing shapes, primarily attributable to complex hydrodynamic interactions over small scales. We show that effect of varied substrate wettability conditions may further…

Fluid Dynamics · Physics 2015-09-11 Kaustav Chaudhury , Debabrata DasGupta , Tamal Roy , Suman Chakraborty

This work has explored interface evolution and pinch-off mechanism of the droplet formation in two-phase flow through cross-flow microfluidic device. The two-dimensional mathematical model equations have been solved using the finite element…

Fluid Dynamics · Physics 2022-03-10 Akepogu Venkateshwarlu , Ram Prakash Bharti

Droplet-based microfluidics turned out to be an efficient and adjustable platform for digital analysis, encapsulation of cells, drug formulation, and polymerase chain reaction. Typically, for most biomedical applications, the handling of…

Soft Condensed Matter · Physics 2018-01-30 Enrico Chiarello , Anupam Gupta , Giampaolo Mistura , Mauro Sbragaglia , Matteo Pierno

Generating droplets from a continuous stream of fluid requires precise tuning of a device to find optimized control parameter conditions. It is analytically intractable to compute the necessary control parameter values of a…

Machine Learning · Computer Science 2022-01-19 Alexander E. Siemenn , Evyatar Shaulsky , Matthew Beveridge , Tonio Buonassisi , Sara M. Hashmi , Iddo Drori
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