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Neurons exhibit intricate geometries within their neurite networks, which play a crucial role in processes such as signaling and nutrient transport. Accurate simulation of material transport in the networks is essential for understanding…

Machine Learning · Computer Science 2025-07-16 Tsung Yeh Hsieh , Yongjie Jessica Zhang

Effective interaction modeling and behavior prediction of dynamic agents play a significant role in interactive motion planning for autonomous robots. Although existing methods have improved prediction accuracy, few research efforts have…

Robotics · Computer Science 2024-01-09 Victoria M. Dax , Jiachen Li , Enna Sachdeva , Nakul Agarwal , Mykel J. Kochenderfer

Mechanistic simulators are an indispensable tool for epidemiology to explore the behavior of complex, dynamic infections under varying conditions and navigate uncertain environments. Agent-based models (ABMs) are an increasingly popular…

Events in natural videos typically arise from spatio-temporal interactions between actors and objects and involve multiple co-occurring activities and object classes. To capture this rich visual and semantic context, we propose using two…

Computer Vision and Pattern Recognition · Computer Science 2020-10-01 Effrosyni Mavroudi , Benjamín Béjar Haro , René Vidal

The rapid advancement of large language models (LLMs) has enabled the development of multi-agent systems where multiple LLM-based agents collaborate on complex tasks. However, existing systems often rely on centralized coordination, leading…

Multiagent Systems · Computer Science 2025-06-02 Yingxuan Yang , Huacan Chai , Shuai Shao , Yuanyi Song , Siyuan Qi , Renting Rui , Weinan Zhang

Directed graphs are a natural model for many phenomena, in particular scientific knowledge graphs such as molecular interaction or chemical reaction networks that define cellular signaling relationships. In these situations, source nodes…

In this paper, we tackle the problem of relational behavior forecasting from sensor data. Towards this goal, we propose a novel spatially-aware graph neural network (SpAGNN) that models the interactions between agents in the scene.…

Computer Vision and Pattern Recognition · Computer Science 2019-10-21 Sergio Casas , Cole Gulino , Renjie Liao , Raquel Urtasun

Longitudinal neuroimaging is essential for modeling disease progression in Alzheimer's disease (AD), yet irregular sampling and missing visits pose substantial challenges for learning reliable temporal representations. To address this…

Machine Learning · Computer Science 2026-03-24 Ruiying Chen , Yutong Wang , Houliang Zhou , Wei Liang , Yong Chen , Lifang He

Agent-based modeling and simulation is a useful method to study biological phenomena in a wide range of fields, from molecular biology to ecology. Since there is currently no agreed-upon standard way to specify such models it is not always…

Quantitative Methods · Quantitative Biology 2010-10-14 Franziska Hinkelmann , David Murrugarra , Abdul Salam Jarrah , Reinhard Laubenbacher

Gene-gene interactions play a crucial role in the manifestation of complex human diseases. Uncovering significant gene-gene interactions is a challenging task. Here, we present an innovative approach utilizing data-driven computational…

Artificial Intelligence · Computer Science 2024-10-22 Yifan Wu , Yuntao Yang , Zirui Liu , Zhao Li , Khushbu Pahwa , Rongbin Li , Wenjin Zheng , Xia Hu , Zhaozhuo Xu

Representation learning in dynamic graphs is a challenging problem because the topology of graph and node features vary at different time. This requires the model to be able to effectively capture both graph topology information and…

Machine Learning · Computer Science 2021-11-16 Xintao Xiang , Tiancheng Huang , Donglin Wang

Data-driven learning of physical systems has kindled significant attention, where many neural models have been developed. In particular, mesh-based graph neural networks (GNNs) have demonstrated significant potential in modeling…

Machine Learning · Computer Science 2025-10-08 Yuan Mi , Qi Wang , Xueqin Hu , Yike Guo , Ji-Rong Wen , Yang Liu , Hao Sun

Deep reinforcement learning in continuous domains focuses on learning control policies that map states to distributions over actions that ideally concentrate on the optimal choices in each step. In multi-agent navigation problems, the…

Robotics · Computer Science 2022-10-20 Chenning Yu , Hongzhan Yu , Sicun Gao

Agent-based models (ABMs) simulate the formation and evolution of social processes at a fundamental level by decoupling agent behavior from global observations. In the case where ABM networks evolve over time as a result of (or in…

Social and Information Networks · Computer Science 2023-08-11 Karleigh Pine , Joel Klipfel , Jared Bennett , Nathaniel Bade , Christian Manasseh

Understanding how neuronal networks reorganize in response to external stimuli and give rise to behavior is a central challenge in neuroscience and artificial intelligence. However, existing methods often fail to capture the evolving…

Neurons and Cognition · Quantitative Biology 2025-06-02 Moein Khajehnejad , Forough Habibollahi , Ahmad Khajehnejad , Chris French , Brett J. Kagan , Adeel Razi

Computational modeling of single-cell gene expression is crucial for understanding cellular processes, but generating realistic expression profiles remains a major challenge. This difficulty arises from the count nature of gene expression…

A cell can be seen as an adaptive autonomous agent or as a society of adaptive autonomous agents, where each can exhibit a particular behaviour depending on its cognitive capabilities. We present an intracellular signalling model obtained…

Multiagent Systems · Computer Science 2007-05-23 Pedro Pablo Gonzalez Perez , Maura Cardenas Garcia , Carlos Gershenson , Jaime Lagunez-Otero

Data-driven graph learning models a network by determining the strength of connections between its nodes. The data refers to a graph signal which associates a value with each graph node. Existing graph learning methods either use simplified…

Machine Learning · Computer Science 2020-11-05 Nafiseh Ghoroghchian , David M. Groppe , Roman Genov , Taufik A. Valiante , Stark C. Draper

Adhesion between cells plays an important role in many biological processes such as tissue morphogenesis and homeostasis, wound healing and cancer cell metastasis. From a mathematical perspective, adhesion between multiple cell types has…

Cell Behavior · Quantitative Biology 2024-04-17 Shahzeb Raja Noureen , Richard L. Mort , Christian A. Yates

Spatio-temporal graphs such as traffic networks or gene regulatory systems present challenges for the existing deep learning methods due to the complexity of structural changes over time. To address these issues, we introduce…

Machine Learning · Computer Science 2019-04-15 Felix L. Opolka , Aaron Solomon , Cătălina Cangea , Petar Veličković , Pietro Liò , R Devon Hjelm