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Medical Decision-Making (MDM) is a multi-faceted process that requires clinicians to assess complex multi-modal patient data patient, often collaboratively. Large Language Models (LLMs) promise to streamline this process by synthesizing…

Large language model multi-agent systems (LLM-MAS) offer a promising paradigm for harnessing collective intelligence to achieve more advanced forms of AI behaviour. While recent studies suggest that LLM-MAS can outperform LLM single-agent…

Artificial Intelligence · Computer Science 2025-10-07 Bohan Tang , Huidong Liang , Keyue Jiang , Xiaowen Dong

Large language models (LLMs) and LLM-based agents are increasingly deployed as assistants in planning and decision making, yet most existing systems are implicitly optimized for a single-principal interaction paradigm, in which the model is…

Computation and Language · Computer Science 2026-04-29 Shu Yang , Shenzhe Zhu , Hao Zhu , José Ramón Enríquez , Di Wang , Alex Pentland , Michiel A. Bakker , Jiaxin Pei

The introduction of large language models (LLMs) has greatly enhanced the capabilities of software agents. Instead of relying on rule-based interactions, agents can now interact in flexible ways akin to humans. However, this flexibility…

Human-Computer Interaction · Computer Science 2026-02-04 Joar Sabel , Mattias Wingren , Andreas Lundell , Sören Andersson , Sara Rosenberg , Susanne Hägglund , Linda Estman , Malin Andtfolk

Large language model-based multi-agent systems have recently gained significant attention due to their potential for complex, collaborative, and intelligent problem-solving capabilities. Existing surveys typically categorize LLM-based…

Multiagent Systems · Computer Science 2026-05-27 Bingyu Yan , Zhibo Zhou , Litian Zhang , Lian Zhang , Ziyi Zhou , Dezhuang Miao , Zhoujun Li , Chaozhuo Li , Xiaoming Zhang

Large language models (LLMs) have proven effective in artificial intelligence, where the multi-agent system (MAS) holds considerable promise for healthcare development by achieving the collaboration of LLMs. However, the absence of a…

Artificial Intelligence · Computer Science 2026-05-13 Zhihao Peng , Liuxin Bao , Yixuan Yuan

Building effective clinical decision support systems requires the synthesis of complex heterogeneous multimodal data. Such modalities include temporal electronic health records data, medical images, radiology reports, and clinical notes.…

Artificial Intelligence · Computer Science 2026-05-12 Baraa Al Jorf , Farah E. Shamout

Large Language Models (LLMs) have made significant progress in various fields. However, challenges remain in Multi-Disciplinary Team (MDT) medical consultations. Current research enhances reasoning through role assignment, task…

Artificial Intelligence · Computer Science 2025-03-19 Kai Chen , Xinfeng Li , Tianpei Yang , Hewei Wang , Wei Dong , Yang Gao

Multi-agent large language model (LLM) systems have emerged as a promising approach for clinical diagnosis, leveraging collaboration among agents to refine medical reasoning. However, most existing frameworks rely on single-vendor teams…

Computation and Language · Computer Science 2026-03-17 Grace Chang Yuan , Xiaoman Zhang , Sung Eun Kim , Pranav Rajpurkar

Background: Cognitive biases in clinical decision-making significantly contribute to errors in diagnosis and suboptimal patient outcomes. Addressing these biases presents a formidable challenge in the medical field. Objective: This study…

Computation and Language · Computer Science 2024-05-14 Yu He Ke , Rui Yang , Sui An Lie , Taylor Xin Yi Lim , Hairil Rizal Abdullah , Daniel Shu Wei Ting , Nan Liu

Large language models (LLMs) demonstrate strong potential as agents for tool invocation due to their advanced comprehension and planning capabilities. Users increasingly rely on LLM-based agents to solve complex missions through iterative…

Artificial Intelligence · Computer Science 2025-04-17 Peijie Yu , Yifan Yang , Jinjian Li , Zelong Zhang , Haorui Wang , Xiao Feng , Feng Zhang

Multi-agent LLM frameworks are widely used to accelerate the development of agent systems powered by large language models (LLMs). These frameworks impose distinct architectural structures that govern how agents interact, store information,…

Artificial Intelligence · Computer Science 2026-02-04 Abdelghny Orogat , Ana Rostam , Essam Mansour

Accurate interpretation of clinical narratives is critical for patient care, but the complexity of these notes makes automation challenging. While Large Language Models (LLMs) show promise, single-model approaches can lack the robustness…

Artificial Intelligence · Computer Science 2025-09-01 Yeawon Lee , Xiaoyang Wang , Christopher C. Yang

Large language models (LLMs) have achieved impressive results in natural language understanding, yet their reasoning capabilities remain limited when operating as single agents. Multi-Agent Debate (MAD) has been proposed to address this…

Computation and Language · Computer Science 2026-03-25 Xiao Wang , Jia Wang , Yijie Wang , Pengtao Dang , Sha Cao , Chi Zhang

Large Language Models (LLMs) have revolutionized Natural Language Processing but exhibit limitations, particularly in autonomously addressing novel challenges such as reasoning and problem-solving. Traditional techniques like…

Multiagent Systems · Computer Science 2024-01-03 Sumedh Rasal

Multi-agent systems (MAS) decompose complex tasks and delegate subtasks to different large language model (LLM) agents and tools. Prior studies have reported the superior accuracy performance of MAS across diverse domains, enabled by…

Multiagent Systems · Computer Science 2025-05-27 Mingyan Gao , Yanzi Li , Banruo Liu , Yifan Yu , Phillip Wang , Ching-Yu Lin , Fan Lai

Large language models (LLMs) have demonstrated strong reasoning, planning, and communication abilities, enabling them to operate as autonomous agents in open environments. While single-agent systems remain limited in adaptability and…

Multiagent Systems · Computer Science 2026-01-22 Jianing Hao , Han Ding , Yuanjian Xu , Tianze Sun , Ran Chen , Wanbo Zhang , Guang Zhang , Siguang Li

With recent advances in Large Language Models (LLMs), Agentic AI has become phenomenal in real-world applications, moving toward multiple LLM-based agents to perceive, learn, reason, and act collaboratively. These LLM-based Multi-Agent…

Artificial Intelligence · Computer Science 2025-01-14 Khanh-Tung Tran , Dung Dao , Minh-Duong Nguyen , Quoc-Viet Pham , Barry O'Sullivan , Hoang D. Nguyen

Large Language Model (LLM)-based Multi-Agent Systems (MAS) enhance complex problem solving through multi-agent collaboration, but often incur substantially higher costs than single-agent systems. Recent MAS routing methods aim to balance…

Multiagent Systems · Computer Science 2026-01-15 Di Zhao , Longhui Ma , Siwei Wang , Miao Wang , Yi Kong

Multi-agent systems (MAS) have emerged as a prominent paradigm for leveraging large language models (LLMs) to tackle complex tasks. However, the mechanisms governing the effectiveness of MAS built upon publicly available LLMs, specifically…

Multiagent Systems · Computer Science 2026-05-11 Yuxuan Zhao , Sijia Chen , Ningxin Su
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