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The advancement of human healthspan and bioengineering relies heavily on predicting the behavior of complex biological systems. While high-throughput multiomics data is becoming increasingly abundant, converting this data into actionable…

Machine Learning · Computer Science 2025-12-10 Udesh Habaraduwa , Andrei Lixandru

Developing neural operators that accurately predict the behavior of systems governed by partial differential equations (PDEs) across unseen parameter regimes is crucial for robust generalization in scientific and engineering applications.…

Machine Learning · Computer Science 2026-04-21 Eva van Tegelen , Taniya Kapoor , George A. K. van Voorn , Peter van Heijster , Ioannis N. Athanasiadis

We develop a novel multi-layer predictor-feedback to achieve exact compensation of state-dependent input delay of general nonlinear integro-differential equations. The system of interest is an unconventional mixed Partial Differential…

Optimization and Control · Mathematics 2026-04-09 Tong Li , Peipei Shang , Mamadou Diagne

In the context of training neural network-based approximations of solutions of parameter-dependent PDEs, we investigate the effect of preconditioning via well-conditioned frame representations of operators and demonstrate a significant…

Numerical Analysis · Mathematics 2026-02-02 Markus Bachmayr , Wolfgang Dahmen , Chenguang Duan , Mathias Oster

The proposed BSDE-based diffusion model represents a novel approach to diffusion modeling, which extends the application of stochastic differential equations (SDEs) in machine learning. Unlike traditional SDE-based diffusion models, our…

Machine Learning · Computer Science 2023-04-27 Zihao Wang

The problem of state estimation for a system of coupled hyperbolic PDEs and ODEs with Lipschitz nonlinearities with boundary measurements is considered. An infinite dimensional observer with a linear boundary injection term is used to solve…

Systems and Control · Electrical Eng. & Systems 2021-01-19 Francesco Ferrante , Andrea Cristofaro

One of the most popular recent areas of machine learning predicates the use of neural networks augmented by information about the underlying process in the form of Partial Differential Equations (PDEs). These physics-informed neural…

Fluid Dynamics · Physics 2025-06-17 Luca Menicali , David H. Richter , Stefano Castruccio

Neural PDE surrogates are often deployed in data-limited or partially observed regimes where downstream decisions depend on calibrated uncertainty in addition to low prediction error. Existing approaches obtain uncertainty through ensemble…

Machine Learning · Computer Science 2026-02-12 Carlos Stein Brito

Operator learning is a recently developed generalization of regression to mappings between functions. It promises to drastically reduce expensive numerical integration of PDEs to fast evaluations of mappings between functional states of a…

Machine Learning · Computer Science 2025-12-23 Tian Yu Yen , Reese E. Jones , Ravi G. Patel

A Neural Process (NP) estimates a stochastic process implicitly defined with neural networks given a stream of data, rather than pre-specifying priors already known, such as Gaussian processes. An ideal NP would learn everything from data…

Machine Learning · Computer Science 2023-04-20 Hyungi Lee , Eunggu Yun , Giung Nam , Edwin Fong , Juho Lee

Motivated by dynamic risk measures and conditional $g$-expectations, in this work we propose a numerical method to approximate the solution operator given by a Backward Stochastic Differential Equation (BSDE). The main ingredients for this…

Numerical Analysis · Mathematics 2025-12-12 Pere Díaz Lozano , Giulia Di Nunno

Recent advances in learning dynamical systems from data have shown significant promise. However, many existing methods assume access to the full state of the system -- an assumption that is rarely satisfied in practice, where systems are…

Machine Learning · Computer Science 2026-03-10 Thibault Monsel , Onofrio Semeraro , Lionel Mathelin , Guillaume Charpiat

Fourier Neural Operators are deep learning models that learn mappings between function spaces and can be used to learn and solve partial differential equations (PDEs), in some cases significantly faster than traditional PDE solvers. Within…

Machine Learning · Computer Science 2026-05-05 Michael F. Staddon

Neural operators provide a framework for learning solution operators of partial differential equations (PDEs), enabling efficient surrogate modeling for complex systems. While universal approximation results are now well understood,…

Machine Learning · Computer Science 2026-05-13 Takashi Furuya , Ryo Ozawa , Jenn-Nan Wang

In this paper, we study a kind of constrained backward stochastic differential equations (BSDEs) such that the nonlinear expectation of the composition of a loss function and the solution remains above zero. The existence and uniqueness…

Probability · Mathematics 2025-11-24 Hanwu Li

We develop a theoretical analysis for special neural network architectures, termed operator recurrent neural networks, for approximating nonlinear functions whose inputs are linear operators. Such functions commonly arise in solution…

Optimization and Control · Mathematics 2022-01-05 Maarten V. de Hoop , Matti Lassas , Christopher A. Wong

Simulation-based inference (SBI) enables parameter estimation for complex stochastic models with intractable likelihoods when model simulation is feasible. Neural posterior estimation (NPE) is a popular SBI approach that often achieves…

Methodology · Statistics 2026-02-23 Ryan P. Kelly , David T. Frazier , David J. Warne , Christopher C. Drovandi

In this work, we propose a new deep learning-based scheme for solving high dimensional nonlinear backward stochastic differential equations (BSDEs). The idea is to reformulate the problem as a global optimization, where the local loss…

Numerical Analysis · Mathematics 2024-04-18 Lorenc Kapllani , Long Teng

A wide range of scientific problems, such as those described by continuous-time dynamical systems and partial differential equations (PDEs), are naturally formulated on function spaces. While function spaces are typically…

We study the derivative-informed learning of nonlinear operators between infinite-dimensional separable Hilbert spaces by neural networks. Such operators can arise from the solution of partial differential equations (PDEs), and are used in…

Numerical Analysis · Mathematics 2025-04-14 Dingcheng Luo , Thomas O'Leary-Roseberry , Peng Chen , Omar Ghattas