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Mild-stage dementia patients primarily experience two critical symptoms: severe memory loss and emotional instability. To address these challenges, we propose DEMENTIA-PLAN, an innovative retrieval-augmented generation framework that…
Alzheimer's disease is estimated to affect around 50 million people worldwide and is rising rapidly, with a global economic burden of nearly a trillion dollars. This calls for scalable, cost-effective, and robust methods for detection of…
In the past decade, there has been a surge in research examining the use of voice and speech analysis as a means of detecting neurodegenerative diseases such as Alzheimer's. Many studies have shown that certain acoustic features can be used…
Dementia and especially Alzheimer's disease (AD) are the most common causes of cognitive decline in elderly people. A spread of the above mentioned mental health problems in aging societies is causing a significant medical and economic…
This paper proposes a speech-based method for automatic depression classification. The system is based on ensemble learning for Convolutional Neural Networks (CNNs) and is evaluated using the data and the experimental protocol provided in…
Dementia is characterized by a decline in memory and thinking that is significant enough to impair function in activities of daily living. Patients seen in dementia specialty clinics are highly heterogeneous with a variety of different…
This paper presents a tutorial of an explainable approach using Convolutional Neural Network (CNN) and Gradient-weighted Class Activation Mapping (Grad-CAM) to classify four progressive dementia stages based on open MRI brain images. The…
Dementia affects cognitive functions of adults, including memory, language, and behaviour. Standard diagnostic biomarkers such as MRI are costly, whilst neuropsychological tests suffer from sensitivity issues in detecting dementia onset.…
Current progress in the artificial intelligence domain has led to the development of various types of AI-powered dementia assessments, which can be employed to identify patients at the early stage of dementia. It can revolutionize the…
Speech, language, and communication deficits are present in most neurodegenerative syndromes. They enable the early detection, diagnosis, treatment planning, and monitoring of neurocognitive disease progression as part of traditional…
Alzheimer's dementia (AD) is a neurodegenerative disorder with cognitive decline that commonly impacts language ability. This work extends the paired perplexity approach to detecting AD by using a recent large language model (LLM), the…
Projected to impact 1.6 million people in the UK by 2040 and costing {\pounds}25 billion annually, dementia presents a growing challenge to society. This study, a pioneering effort to predict the translational potential of dementia research…
Dementia is under-recognized in the community, under-diagnosed by healthcare professionals, and under-coded in claims data. Information on cognitive dysfunction, however, is often found in unstructured clinician notes within medical records…
Simulating dementia patients with large language models (LLMs) is challenging due to the need to jointly model cognitive impairment, emotional dynamics, and nonverbal behaviors over long conversations. We present DemMA, an expert-guided…
Speech pause is an effective biomarker in dementia detection. Recent deep learning models have exploited speech pauses to achieve highly accurate dementia detection, but have not exploited the interpretability of speech pauses, i.e., what…
There is a pressing need to automatically understand the state and progression of chronic neurological diseases such as dementia. The emergence of state-of-the-art sensing platforms offers unprecedented opportunities for indirect and…
Alzheimer's Disease (AD) is nowadays the most common form of dementia, and its automatic detection can help to identify symptoms at early stages, so that preventive actions can be carried out. Moreover, non-intrusive techniques based on…
Interpreting the environmental, behavioural and psychological data from in-home sensory observations and measurements can provide valuable insights into the health and well-being of individuals. Presents of neuropsychiatric and…
Dementia is a progressive cognitive syndrome with Alzheimer's disease (AD) as the leading cause. Conversation-based AD detection offers a cost-effective alternative to clinical methods, as language dysfunction is an early biomarker of AD.…
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that leads to irreversible cognitive decline in memory and communication. Early detection of AD through speech analysis is crucial for delaying disease progression.…