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Real-time monitoring of dynamic biological processes in the body is critical to understanding disease progression and treatment response. This data, for instance, can help address the lower than 50% response rates to cancer immunotherapy.…

Monitoring diseases that affect the brain's structural integrity requires automated analysis of magnetic resonance (MR) images, e.g., for the evaluation of volumetric changes. However, many of the evaluation tools are optimized for…

Today, over 700,000 people are living with brain tumors in the United States. Brain tumors can spread very quickly to other parts of the brain and the spinal cord unless necessary preventive action is taken. Thus, the survival rate for this…

Computer Vision and Pattern Recognition · Computer Science 2020-11-18 Sahithi Ankireddy

Deep learning has demonstrated significant potential in medical imaging; however, the opacity of "black-box" models hinders clinical trust, while segmentation tasks typically necessitate labourious, hard-to-obtain pixel-wise annotations. To…

Image and Video Processing · Electrical Eng. & Systems 2026-01-22 Soumick Chatterjee , Hadya Yassin , Florian Dubost , Andreas Nürnberger , Oliver Speck

Predicting the sensitivity of cancer cell lines to PLX-4720, a preclinical BRAF inhibitor, requires models capable of capturing the multilayered regulation of oncogenic signaling. Single-omics predictors are often insufficient because drug…

Brain tumors analysis is important in timely diagnosis and effective treatment to cure patients. Tumor analysis is challenging because of tumor morphology like size, location, texture, and heteromorphic appearance in the medical images. In…

Image and Video Processing · Electrical Eng. & Systems 2022-02-14 Mirza Mumtaz Zahoor , Shahzad Ahmad Qureshi , Saddam Hussain Khan , Asifullah Khan

Current analysis of tumor proliferation, the most salient prognostic biomarker for invasive breast cancer, is limited to subjective mitosis counting by pathologists in localized regions of tissue images. This study presents the first…

Computer Vision and Pattern Recognition · Computer Science 2016-10-12 Manan Shah , Christopher Rubadue , David Suster , Dayong Wang

In the past few years, deep learning (DL) models have drawn great attention and shown superior performance on brain tumor and subregion segmentation tasks. However, the success is limited to segmentation of adult gliomas, where sufficient…

Image and Video Processing · Electrical Eng. & Systems 2021-10-01 Silu Zhang , Angela Edwards , Shubo Wang , Zoltan Patay , Asim Bag , Matthew A. Scoggins

Computer-aided segmentation of brain tumors from MRI data is of crucial significance to clinical decision-making in diagnosis, treatment planning, and follow-up disease monitoring. Gliomas, owing to their high malignancy and heterogeneity,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-25 MD Rashidul Islam , Bakary Gibba

Brain tumor detection and classification are critical tasks in medical image analysis, particularly in early-stage diagnosis, where accurate and timely detection can significantly improve treatment outcomes. In this study, we apply various…

Computer Vision and Pattern Recognition · Computer Science 2024-11-08 Alice Oh , Inyoung Noh , Jian Choo , Jihoo Lee , Justin Park , Kate Hwang , Sanghyeon Kim , Soo Min Oh

Accurate subtype classification and outcome prediction in mesothelioma are essential for guiding therapy and patient care. Most computational pathology models are trained on large tissue images from resection specimens, limiting their use…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Farzaneh Seyedshahi , Francesca Damiola , Sylvie Lantuejoul , Ke Yuan , John Le Quesne

The most common primary brain tumors are gliomas, evolving from the cerebral supportive cells. For clinical follow-up, the evaluation of the preoperative tumor volume is essential. Volumetric assessment of tumor volume with manual…

Computer Vision and Pattern Recognition · Computer Science 2011-03-11 Jan Egger , Dženan Zukić , Miriam H. A. Bauer , Daniela Kuhnt , Barbara Carl , Bernd Freisleben , Andreas Kolb , Christopher Nimsky

In recent years, the diagnosis of gliomas has become increasingly complex. Analysis of glioma histopathology images using artificial intelligence (AI) offers new opportunities to support diagnosis and outcome prediction. To give an overview…

$^{18}$F-Fluoromisonidazole ($^{18}$F-FMISO) is a highly promising positron emission tomography radiopharmaceutical for identifying hypoxic regions in solid tumors. This research employs spatiotemporal multi-scale mathematical modeling to…

Biological Physics · Physics 2024-05-08 Mohammad Amin Abazari , M. Soltani , Faezeh Eydi , Arman Rahmim , Farshad Moradi Kashkooli

Phase contrast X-ray imaging (PCXI) is an emerging imaging modality that has the potential to greatly improve radiography for medical imaging and materials analysis. PCXI makes it possible to visualise soft-tissue structures that are…

Confocal laser endomicroscopy (CLE) is an advanced optical fluorescence technology undergoing assessment for applications in brain tumor surgery. Despite its promising potential, interpreting the unfamiliar gray tone images of fluorescent…

Computer Vision and Pattern Recognition · Computer Science 2018-08-21 Mohammadhassan Izadyyazdanabadi , Evgenii Belykh , Michael Mooney , Nikolay Martirosyan , Jennifer Eschbacher , Peter Nakaji , Mark C. Preul , Yezhou Yang

Neuro-oncological surgery is the primary brain cancer treatment, yet it faces challenges with gliomas due to their invasiveness and the need to preserve neurological function. Hence, radical resection is often unfeasible, highlighting the…

The research work presented in this paper is to achieve the tissue classification and automatically diagnosis the abnormal tumor region present in Computed Tomography (CT) images using the wavelet based statistical texture analysis method.…

Computer Vision and Pattern Recognition · Computer Science 2015-03-13 A. Padma , Dr. R. Sukanesh

Tumors can manifest in various forms and in different areas of the human body. Brain tumors are specifically hard to diagnose and treat because of the complexity of the organ in which they develop. Detecting them in time can lower the…

Image and Video Processing · Electrical Eng. & Systems 2024-03-18 Antonio Curci , Andrea Esposito

Data limitation is a significant challenge in applying deep learning to medical images. Recently, the diffusion probabilistic model (DPM) has shown the potential to generate high-quality images by converting Gaussian random noise into…

Computer Vision and Pattern Recognition · Computer Science 2024-08-26 Sepehr Salem Ghahfarokhi , Tyrell To , Julie Jorns , Tina Yen , Bing Yu , Dong Hye Ye