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Handwriting stroke generation is crucial for improving the performance of tasks such as handwriting recognition and writers order recovery. In handwriting stroke generation, it is significantly important to imitate the sample calligraphic…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Sidra Hanif , Longin Jan Latecki

We propose a diffusion-based approach for Text-to-Image (T2I) generation with consistent and interactive 3D layout control and editing. While prior methods improve spatial adherence using 2D cues or iterative copy-warp-paste strategies,…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Andrea Rigo , Luca Stornaiuolo , Weijie Wang , Mauro Martino , Bruno Lepri , Nicu Sebe

In this study, we aim to enhance the capabilities of diffusion-based text-to-image (T2I) generation models by integrating diverse modalities beyond textual descriptions within a unified framework. To this end, we categorize widely used…

Computer Vision and Pattern Recognition · Computer Science 2025-08-27 Sungnyun Kim , Junsoo Lee , Kibeom Hong , Daesik Kim , Namhyuk Ahn

Graph generation is a critical yet challenging task, as empirical analyses require a deep understanding of complex, non-Euclidean structures. Diffusion models have recently made significant advances in graph generation, but these models are…

Machine Learning · Computer Science 2026-03-13 Yiming Huang , Tolga Birdal

Equivariant diffusion models have emerged as the prevailing approach for generating novel crystal materials due to their ability to leverage the physical symmetries of periodic material structures. However, current models do not effectively…

Machine Learning · Computer Science 2025-03-04 Kishalay Das , Subhojyoti Khastagir , Pawan Goyal , Seung-Cheol Lee , Satadeep Bhattacharjee , Niloy Ganguly

Most evaluations of generative models rely on feature-distribution metrics such as FID, which operate on continuous recognition features that are explicitly trained to be invariant to appearance variations, and thus discard cues critical…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Zexi Jia , Pengcheng Luo , Yijia Zhong , Jinchao Zhang , Jie Zhou

Diffusion models have emerged as a leading framework in generative modeling, poised to transform the traditionally slow and costly process of drug discovery. This review provides a systematic comparison of their application in designing two…

Machine Learning · Computer Science 2025-11-27 Yiquan Wang , Yahui Ma , Yuhan Chang , Jiayao Yan , Jialin Zhang , Minnuo Cai , Kai Wei

In this work, we present RadGazeGen, a novel framework for integrating experts' eye gaze patterns and radiomic feature maps as controls to text-to-image diffusion models for high fidelity medical image generation. Despite the recent success…

Computer Vision and Pattern Recognition · Computer Science 2024-10-02 Moinak Bhattacharya , Gagandeep Singh , Shubham Jain , Prateek Prasanna

Designing new molecules is essential for drug discovery and material science. Recently, deep generative models that aim to model molecule distribution have made promising progress in narrowing down the chemical research space and generating…

Biomolecules · Quantitative Biology 2023-06-06 Han Huang , Leilei Sun , Bowen Du , Weifeng Lv

We consider the problem of conditional text-to-image synthesis with diffusion models. Most recent works need to either finetune specific parts of the base diffusion model or introduce new trainable parameters, leading to deployment…

Computer Vision and Pattern Recognition · Computer Science 2024-11-19 Tripti Shukla , Srikrishna Karanam , Balaji Vasan Srinivasan

Generating stylistic text with specific attributes is a key problem in controllable text generation. Recently, diffusion models have emerged as a powerful paradigm for both visual and textual generation. Existing approaches can be broadly…

Computation and Language · Computer Science 2025-10-09 Fan Zhou , Chang Tian , Tim Van de Cruys

Recent advances in diffusion models have shown remarkable potential in the conditional generation of novel molecules. These models can be guided in two ways: (i) explicitly, through additional features representing the condition, or (ii)…

Machine Learning · Computer Science 2025-03-12 Yuchen Shen , Chenhao Zhang , Sijie Fu , Chenghui Zhou , Newell Washburn , Barnabás Póczos

Generating ligand molecules for specific protein targets, known as structure-based drug design, is a fundamental problem in therapeutics development and biological discovery. Recently, target-aware generative models, especially diffusion…

Biomolecules · Quantitative Biology 2024-10-29 Siyi Gu , Minkai Xu , Alexander Powers , Weili Nie , Tomas Geffner , Karsten Kreis , Jure Leskovec , Arash Vahdat , Stefano Ermon

Generative AI presents chemists with novel ideas for drug design and facilitates the exploration of vast chemical spaces. Diffusion models (DMs), an emerging tool, have recently attracted great attention in drug R\&D. This paper…

Biomolecules · Quantitative Biology 2025-07-14 Peining Zhang , Daniel Baker , Minghu Song , Jinbo Bi

Recent advances in text-to-image diffusion models have enabled the photorealistic generation of images from text prompts. Despite the great progress, existing models still struggle to generate compositional multi-concept images naturally,…

Computer Vision and Pattern Recognition · Computer Science 2023-10-12 Hazarapet Tunanyan , Dejia Xu , Shant Navasardyan , Zhangyang Wang , Humphrey Shi

The conditional text-to-image diffusion models have garnered significant attention in recent years. However, the precision of these models is often compromised mainly for two reasons, ambiguous condition input and inadequate condition…

Computer Vision and Pattern Recognition · Computer Science 2024-03-28 Sicheng Li , Keqiang Sun , Zhixin Lai , Xiaoshi Wu , Feng Qiu , Haoran Xie , Kazunori Miyata , Hongsheng Li

We present a novel image editing scenario termed Text-grounded Object Generation (TOG), defined as generating a new object in the real image spatially conditioned by textual descriptions. Existing diffusion models exhibit limitations of…

Computer Vision and Pattern Recognition · Computer Science 2024-03-18 Xiangtian Xue , Jiasong Wu , Youyong Kong , Lotfi Senhadji , Huazhong Shu

Developing new molecular compounds is crucial to address pressing challenges, from health to environmental sustainability. However, exploring the molecular space to discover new molecules is difficult due to the vastness of the space. Here…

Machine Learning · Computer Science 2025-05-23 Manuel Ruiz-Botella , Marta Sales-Pardo , Roger Guimerà

Semantic image synthesis (SIS) is a task to generate realistic images corresponding to semantic maps (labels). However, in real-world applications, SIS often encounters noisy user inputs. To address this, we propose Stochastic Conditional…

Computer Vision and Pattern Recognition · Computer Science 2024-06-04 Juyeon Ko , Inho Kong , Dogyun Park , Hyunwoo J. Kim

Objective: While recent advances in text-conditioned generative models have enabled the synthesis of realistic medical images, progress has been largely confined to 2D modalities such as chest X-rays. Extending text-to-image generation to…

Computer Vision and Pattern Recognition · Computer Science 2025-10-02 Daniele Molino , Camillo Maria Caruso , Filippo Ruffini , Paolo Soda , Valerio Guarrasi
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