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We introduce and analyze a novel quantum machine learning model motivated by convolutional neural networks. Our quantum convolutional neural network (QCNN) makes use of only $O(\log(N))$ variational parameters for input sizes of $N$ qubits,…

Quantum Physics · Physics 2019-10-23 Iris Cong , Soonwon Choi , Mikhail D. Lukin

Machine learning with hierarchical quantum circuits, usually referred to as Quantum Convolutional Neural Networks (QCNNs), is a promising prospect for near-term quantum computing. The QCNN is a circuit model inspired by the architecture of…

Quantum Physics · Physics 2024-03-05 Matt Lourens , Ilya Sinayskiy , Daniel K. Park , Carsten Blank , Francesco Petruccione

Swift discovery of spin-crossover materials for their potential application in quantum information devices requires techniques which enable efficient identification of suitably bistable candidates. To this end, we screened the Cambridge…

Quantum machine learning (QML) holds promise for computational advantage, yet progress on real-world tasks is hindered by classical preprocessing and noisy devices. We introduce ViT-QCNN-FT, a hybrid framework that integrates a fine-tuned…

Quantum Physics · Physics 2025-10-15 Mingzhu Wang , Yun Shang

Since classical machine learning has become a powerful tool for developing data-driven algorithms, quantum machine learning is expected to similarly impact the development of quantum algorithms. The literature reflects a mutually beneficial…

Quantum Physics · Physics 2024-12-13 Leandro C. Souza , Bruno C. Guingo , Gilson Giraldi , Renato Portugal

Noise is the central obstacle to building large-scale quantum computers. Quantum systems with sufficiently uncorrelated and weak noise could be used to solve computational problems that are intractable with current digital computers. There…

Quantum Physics · Physics 2021-04-19 Robin Harper , Steven T. Flammia , Joel J. Wallman

Quantum-inspired neural network is one of the interesting researches at the junction of the two fields of quantum computing and deep learning. Several models of quantum-inspired neurons with real parameters have been proposed, which are…

Quantum convolutional neural networks (QCNNs) offer a promising architecture for near-term quantum machine learning by combining hierarchical feature extraction with modest parameter growth. However, any QCNN operating on classical data…

Quantum Physics · Physics 2025-12-16 Xingyun Feng

Entanglement is a key quantity for characterizing quantum correlations in particle scattering processes, but its direct evaluation is computationally demanding on quantum hardware. In this work, we investigate whether fermion density…

Quantum Physics · Physics 2026-04-08 Hala Elhag , Yahui Chai

The accurate screening of candidate drug ligands against target proteins through computational approaches is of prime interest to drug development efforts. Such virtual screening depends in part on methods to predict the binding affinity…

Machine Learning · Computer Science 2024-10-22 Ho-Joon Lee , Prashant S. Emani , Mark B. Gerstein

This work presents a quantum convolutional neural network (QCNN) for the classification of high energy physics events. The proposed model is tested using a simulated dataset from the Deep Underground Neutrino Experiment. The proposed…

Machine Learning · Computer Science 2020-12-23 Samuel Yen-Chi Chen , Tzu-Chieh Wei , Chao Zhang , Haiwang Yu , Shinjae Yoo

Accurately predicting protein structures from amino acid sequences remains a fundamental challenge in computational biology, with profound implications for understanding biological functions and enabling structure-based drug discovery.…

Predicting a ligand's bound pose to a target protein is a key component of early-stage computational drug discovery. Recent developments in machine learning methods have focused on improving pose quality at the cost of model runtime. For…

Biomolecules · Quantitative Biology 2024-10-23 Wojtek Treyde , Seohyun Chris Kim , Nazim Bouatta , Mohammed AlQuraishi

Well-known quantum machine learning techniques, namely quantum kernel assisted support vector machines (QSVMs) and quantum convolutional neural networks (QCNNs), are applied to the binary classification of pulsars. In this comparitive study…

Quantum Physics · Physics 2024-09-09 Donovan Slabbert , Matt Lourens , Francesco Petruccione

Many recent machine learning tasks resort to quantum computing to improve classification accuracy and training efficiency by taking advantage of quantum mechanics, known as quantum machine learning (QML). The variational quantum circuit…

Quantum Physics · Physics 2022-08-17 Jindi Wu , Zeyi Tao , Qun Li

Pneumonia poses a significant global health challenge, demanding accurate and timely diagnosis. While deep learning, particularly Convolutional Neural Networks (CNNs), has shown promise in medical image analysis for pneumonia detection,…

Machine Learning · Computer Science 2025-10-29 Gazi Tanbhir , Md. Farhan Shahriyar , Abdullah Md Raihan Chy

Deep neural networks (DNNs) can be made hardware-efficient by reducing the numerical precision of the weights and activations of the network and by improving the network's resilience to noise. However, this gain in efficiency often comes at…

This work investigates use of equivariant neural networks as efficient and high-performance frameworks for image reconstruction and denoising in nuclear medicine. Our work aims to tackle limitations of conventional Convolutional Neural…

Image and Video Processing · Electrical Eng. & Systems 2025-02-03 Amirreza Hashemi , Yuemeng Feng , Arman Rahmim , Hamid Sabet

Quantum machine learning, focusing on quantum neural networks (QNNs), remains a vastly uncharted field of study. Current QNN models primarily employ variational circuits on an ansatz or a quantum feature map, often requiring multiple…

Quantum Physics · Physics 2024-02-02 Utkarsh Singh , Aaron Z. Goldberg , Khabat Heshami

Computational drug discovery provides an efficient tool helping large scale lead molecules screening. One of the major tasks of lead discovery is identifying molecules with promising binding affinities towards a target, a protein in…

Biological Physics · Physics 2019-09-18 Liangzhen Zheng , Jingrong Fan , Yuguang Mu