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Brain lesion segmentation plays an essential role in neurological research and diagnosis. As brain lesions can be caused by various pathological alterations, different types of brain lesions tend to manifest with different characteristics…

Image and Video Processing · Electrical Eng. & Systems 2024-07-17 Xinru Zhang , Ni Ou , Berke Doga Basaran , Marco Visentin , Mengyun Qiao , Renyang Gu , Cheng Ouyang , Yaou Liu , Paul M. Matthew , Chuyang Ye , Wenjia Bai

Accurate brain lesion delineation is important for planning neurosurgical treatment. Automatic brain lesion segmentation methods based on convolutional neural networks have demonstrated remarkable performance. However, neural network…

Image and Video Processing · Electrical Eng. & Systems 2024-08-20 Jiayu Huo , Sebastien Ourselin , Rachel Sparks

Deep learning frameworks such as nnU-Net achieve state-of-the-art performance in brain lesion segmentation but remain difficult to deploy clinically due to heavy dependencies and monolithic design. We introduce \textit{StrokeSeg}, a modular…

Computer Vision and Pattern Recognition · Computer Science 2025-10-29 Yann Kerverdo , Florent Leray , Youwan Mahé , Stéphanie Leplaideur , Francesca Galassi

Understanding the intensity characteristics of brain lesions is key for defining image-based biomarkers in neurological studies and for predicting disease burden and outcome. In this work, we present a novel foreground-based generative…

Image and Video Processing · Electrical Eng. & Systems 2022-08-04 Berke Doga Basaran , Mengyun Qiao , Paul M. Matthews , Wenjia Bai

The segmentation of substantial brain lesions is a significant and challenging task in the field of medical image segmentation. Substantial brain lesions in brain imaging exhibit high heterogeneity, with indistinct boundaries between lesion…

Computer Vision and Pattern Recognition · Computer Science 2025-08-07 Hongming Wang , Yifeng Wu , Huimin Huang , Hongtao Wu , Jia-Xuan Jiang , Xiaodong Zhang , Hao Zheng , Xian Wu , Yefeng Zheng , Jinping Xu , Jing Cheng

Summary Brain Predictability toolbox (BPt) represents a unified framework of machine learning (ML) tools designed to work with both tabulated data (in particular brain, psychiatric, behavioral, and physiological variables) and neuroimaging…

Machine Learning · Computer Science 2020-11-04 Sage Hahn , Dekang Yuan , Wesley Thompson , Max M Owens , Nicholas Allgaier , Hugh Garavan

Robust and generalizable segmentation of brain tumors on multi-parametric magnetic resonance imaging (MRI) remains difficult because tumor types differ widely. The BraTS 2025 Lighthouse Challenge benchmarks segmentation methods on diverse…

Neural demyelination and brain damage accumulated in white matter appear as hyperintense areas on T2-weighted MRI scans in the form of lesions. Modeling binary images at the population level, where each voxel represents the existence of a…

Methodology · Statistics 2023-05-29 Anna Menacher , Thomas E. Nichols , Chris Holmes , Habib Ganjgahi

Automated brain tumor segmentation methods have become well-established and reached performance levels offering clear clinical utility. These methods typically rely on four input magnetic resonance imaging (MRI) modalities: T1-weighted…

Data sharing is a key factor for ensuring reproducibility and transparency of scientific experiments, and neuroimaging is no exception. The vast heterogeneity of data formats and imaging modalities utilised in the field makes it a very…

Digital Libraries · Computer Science 2019-06-25 Unai Lopez-Novoa , Cyril Charron , John Evans , Leandro Beltrachini

The integration of artificial intelligence (AI) into pathology is advancing precision medicine by improving diagnosis, treatment planning, and patient outcomes. Digitised whole-slide images (WSIs) capture rich spatial and morphological…

Creating tetrahedral meshes with anatomically accurate surfaces is critically important for a wide range of model-based neuroimaging modalities. However, computationally efficient brain meshing algorithms and software are greatly lacking.…

Medical Physics · Physics 2017-08-31 Anh Phong Tran , Qianqian Fang

Current deep learning-based approaches to lesion segmentation in neuroimaging often depend on high-resolution images and extensive annotated data, limiting clinical applicability. This paper introduces a novel synthetic data framework…

Image and Video Processing · Electrical Eng. & Systems 2025-08-18 Liam Chalcroft , Ioannis Pappas , Cathy J. Price , John Ashburner

Semantic segmentation of brain tumours is a fundamental task in medical image analysis that can help clinicians in diagnosing the patient and tracking the progression of any malignant entities. Accurate segmentation of brain lesions is…

Image and Video Processing · Electrical Eng. & Systems 2023-08-29 Aditya Kasliwal , Sankarshanaa Sagaram , Laven Srivastava , Pratinav Seth , Adil Khan

Artificial intelligence (AI) is increasingly central to understanding how the brain processes information. However, the integration of neuroscience and modern AI is bottlenecked by a fragmented software ecosystem. Current tools are siloed…

ivadomed is an open-source Python package for designing, end-to-end training, and evaluating deep learning models applied to medical imaging data. The package includes APIs, command-line tools, documentation, and tutorials. ivadomed also…

Image and Video Processing · Electrical Eng. & Systems 2020-10-26 Charley Gros , Andreanne Lemay , Olivier Vincent , Lucas Rouhier , Anthime Bucquet , Joseph Paul Cohen , Julien Cohen-Adad

The field of computer vision is undergoing a paradigm shift toward large-scale foundation model pre-training via self-supervised learning (SSL). Leveraging large volumes of unlabeled brain MRI data, such models can learn anatomical priors…

Image and Video Processing · Electrical Eng. & Systems 2026-01-15 Petros Koutsouvelis , Matej Gazda , Leroy Volmer , Sina Amirrajab , Kamil Barbierik , Branislav Setlak , Jakub Gazda , Peter Drotar

Molecular simulations are an important tool for research in physics, chemistry, and biology. The capabilities of simulations can be greatly expanded by providing access to advanced sampling methods and techniques that permit calculation of…

MELAGE, a pioneering Python-based neuroimaging software, emerges as a versatile tool for the visualization, processing, and analysis of medical images. Initially conceived to address the unique challenges of processing 3D ultrasound and MRI…

Image and Video Processing · Electrical Eng. & Systems 2023-09-15 Bahram Jafrasteh , Simón Pedro Lubián López , Isabel Benavente Fernández

In clinical practice, segmenting specific lesions based on the needs of physicians can significantly enhance diagnostic accuracy and treatment efficiency. However, conventional lesion segmentation models lack the flexibility to distinguish…

Computer Vision and Pattern Recognition · Computer Science 2025-04-22 Shuyi Ouyang , Jinyang Zhang , Xiangye Lin , Xilai Wang , Qingqing Chen , Yen-Wei Chen , Lanfen Lin
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