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200 papers

High-throughput computational screening of polymers offers a powerful way to address the imbalance between the vast number of polymers synthesised for diverse applications and the relatively small subset that can be studied using atomistic…

Materials Science · Physics 2026-03-12 Lois Smith , Samuel Ericson , Vittoria Fantauzzo , Chin Yong , Paola Carbone , Alessandro Troisi

Protein language models (PLMs) have revolutionised computational biology through their ability to generate powerful sequence representations for diverse prediction tasks. However, their black-box nature limits biological interpretation and…

Biomolecules · Quantitative Biology 2025-04-11 Jan van Eck , Dea Gogishvili , Wilson Silva , Sanne Abeln

Post-merger integration (PMI) planning presents significant challenges due to the complex interdependencies between integration initiatives and their associated synergies. While dependency-based planning approaches offer valuable…

Human-Computer Interaction · Computer Science 2025-03-24 Lars Malmqvist

Machine Learning (ML) is profoundly reshaping the way researchers create, implement, and operate data-intensive software. Its adoption, however, introduces notable challenges for computing infrastructures, particularly when it comes to…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-10-30 Lucio Anderlini , Giulio Bianchini , Diego Ciangottini , Stefano Dal Pra , Diego Michelotto , Rosa Petrini , Daniele Spiga

Cloud systems have rapidly expanded worldwide in the last decade, shifting computational tasks to cloud servers where clients submit their requests. Among cloud workloads, latency-critical applications -- characterized by high-percentile…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-05-07 Zhilin Li , Lucia Pons , Salvador Petit , Julio Sahuquillo , Julio Pons

We developed a multiscale approach (MultiSCAAL) that integrates the potential of mean force (PMF) obtained from all-atomistic molecular dynamics simulations with a knowledge-based energy function for coarse-grained molecular simulations in…

Biological Physics · Physics 2010-05-10 Antonios Samiotakis , Dirar Homouz , Margaret S. Cheung

Protein structure determination has long been one of the primary challenges of structural biology, to which deep machine learning (ML)-based approaches have increasingly been applied. However, these ML models generally do not incorporate…

Biological Physics · Physics 2025-11-14 Tom Pan , Evan Dramko , Mitchell D. Miller , Anastasios Kyrillidis , George N. Phillips

We present an end-to-end automated workflow that uses large-scale remote compute resources and an embedded GPU platform at the edge to enable AI/ML-accelerated real-time analysis of data collected for x-ray ptychography. Ptychography is a…

Computer Vision and Pattern Recognition · Computer Science 2023-04-11 Anakha V Babu , Tekin Bicer , Saugat Kandel , Tao Zhou , Daniel J. Ching , Steven Henke , Siniša Veseli , Ryan Chard , Antonino Miceli , Mathew Joseph Cherukara

Computational pathology, which involves analyzing whole slide images for automated cancer diagnosis, relies on multiple instance learning, where performance depends heavily on the feature extractor and aggregator. Recent Pathology…

Computer Vision and Pattern Recognition · Computer Science 2025-05-22 Conghao Xiong , Hao Chen , Joseph J. Y. Sung

Current trends point to a future where large-scale scientific applications are tightly-coupled HPC/AI hybrids. Hence, we urgently need to invest in creating a seamless, scalable framework where HPC and AI/ML can efficiently work together…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-05-06 Jens Domke , Mohamed Wahib , Anshu Dubey , Tal Ben-Nun , Erik W. Draeger

This paper aims to create a transition path from file-based IO to streaming-based workflows for scientific applications in an HPC environment. By using the openPMP-api, traditional workflows limited by filesystem bottlenecks can be overcome…

Cloud native solutions are widely applied in various fields, placing higher demands on the efficient management and utilization of resource platforms. To achieve the efficiency, load forecasting and elastic scaling have become crucial…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-05-22 Linfeng Wen , Minxian Xu , Adel N. Toosi , Kejiang Ye

Understanding inter-VM interference is of paramount importance to provide a sound knowledge and understand where performance degradation comes from in the current public cloud. With this aim, this paper devises a workload taxonomy that…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-10-13 Lucia Pons , Josué Feliu , José Puche , Chaoyi Huang , Salvador Petit , Julio Pons , María E. Gómez , Julio Sahuquillo

In recent years, the integration of artificial intelligence (AI) and cloud computing has emerged as a promising avenue for addressing the growing computational demands of AI applications. This paper presents a comprehensive study of…

Machine Learning · Computer Science 2023-04-28 Neelesh Mungoli

Cloud computing is one of the highly flexible, confidential and easily accessible medium of platforms and provides powerful service for sharing information over the Internet. Cloud security has become an emerging issue as network manager…

Networking and Internet Architecture · Computer Science 2020-06-24 Ziaur Rahman , Asma Islam Swapna , Habibur Rahman Habib , Akramuzzaman Shaoun

Accurate workload forecasting is critical for efficient resource management in cloud computing systems, enabling effective scheduling and autoscaling. Despite recent advances with transformer-based forecasting models, challenges remain due…

Machine Learning · Computer Science 2024-08-20 Shiyu Wang , Zhixuan Chu , Yinbo Sun , Yu Liu , Yuliang Guo , Yang Chen , Huiyang Jian , Lintao Ma , Xingyu Lu , Jun Zhou

In many domains, the previous decade was characterized by increasing data volumes and growing complexity of computational workloads, creating new demands for highly data-parallel computing in distributed systems. Effective operation of…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-01-25 Carl Witt , Marc Bux , Wladislaw Gusew , Ulf Leser

Cloud performance fluctuates due to factors such as resource contention and workload changes. These factors can be short-term, seasonal, or long-term. Their effects are often intertwined in performance traces, making performance management…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-05-12 Shimul Debnath , William Hart , Lori Pollock , Donald Lien , Wei Wang

Cloud service providers commonly use standard benchmarks like TPC-H and TPC-DS to evaluate and optimize cloud data analytics systems. However, these benchmarks rely on fixed query patterns and fail to capture the real execution statistics…

The pre-trained model (PTM) is revolutionizing Artificial Intelligence (AI) technology. However, the hardware requirement of PTM training is prohibitively high, making it a game for a small proportion of people. Therefore, we proposed…

Machine Learning · Computer Science 2022-11-11 Jiarui Fang , Zilin Zhu , Shenggui Li , Hui Su , Yang Yu , Jie Zhou , Yang You