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Quantum noise in real-world devices poses a significant challenge in achieving practical quantum advantage, since accurately compiled and executed circuits are typically deep and highly susceptible to decoherence. To facilitate the…

Quantum Physics · Physics 2025-06-13 Yuchen Guo , Shuo Yang

Quantum computing (QC) provides a promising avenue toward enabling quantum chemistry calculations, which are classically impossible due to a computational complexity that increases exponentially with system size. As fully fault-tolerant…

The synthesis approaches for quantum circuits typically aim at minimizing the number of lines or gates. Given the tight restrictions on those logical resources in physical implementations, we propose to view the problem fundamentally…

Emerging Technologies · Computer Science 2023-02-03 Niels Gleinig , Tobias Rohner , Torsten Hoefler

Quantum computing is a promising technology that harnesses the peculiarities of quantum mechanics to deliver computational speedups for some problems that are intractable to solve on a classical computer. Current generation noisy…

Numerical Analysis · Mathematics 2022-09-16 Daan Camps , Efekan Kökcü , Lindsay Bassman , Wibe A. de Jong , Alexander F. Kemper , Roel Van Beeumen

Quantum algorithm design usually assumes access to a perfect quantum computer with ideal properties like full connectivity, noise-freedom and arbitrarily long coherence time. In Noisy Intermediate-Scale Quantum (NISQ) devices, however, the…

Quantum Physics · Physics 2020-09-11 Xiangzhen Zhou , Sanjiang Li , Yuan Feng

Distributed quantum computation is often proposed to increase the scalability of quantum hardware, as it reduces cooperative noise and requisite connectivity by sharing quantum information between distant quantum devices. However, such…

Quantum Physics · Physics 2023-09-13 Abigail McClain Gomez , Taylor L. Patti , Anima Anandkumar , Susanne F. Yelin

Quantum computing has emerged as a promising platform for simulating strongly correlated systems in chemistry, for which the standard quantum chemistry methods are either qualitatively inaccurate or too expensive. However, due to the…

Chemical Physics · Physics 2024-05-06 Max Rossmannek , Fabijan Pavošević , Angel Rubio , Ivano Tavernelli

Quantum data loading plays a central role in quantum algorithms and quantum information processing. Many quantum algorithms hinge on the ability to prepare arbitrary superposition states as a subroutine, with claims of exponential speedups…

Quantum Physics · Physics 2025-09-25 Chun-Tse Li , Hao-Chung Cheng

A central problem in biophysics and computational drug design is accurate modeling of biomolecules. The current molecular dynamics simulation methods can answer how a molecule inhibits a cancerous cell signaling pathway, or the role of…

Quantum Physics · Physics 2019-10-31 Anurag Mishra , Alireza Shabani

Quantum circuit optimization - the process of transforming a quantum circuit into an equivalent one with reduced time and space requirements - is crucial for maximizing the utility of current and near-future quantum devices. While most…

Quantum Physics · Physics 2026-01-23 Marcin Szyniszewski , Aleks Kissinger , Noah Linden , Paul Skrzypczyk

Accurate calculation of strongly correlated electronic systems requires proper treatment of both static and dynamic correlations, which remains challenging for conventional methods. To address this, we present VQE-PDFT,aquantum-classical…

Quantum Physics · Physics 2026-04-20 Yibo Chen , Zirui Sheng , Weitang Li , Yong Zhang , Xun Xu , Jun-Han Huang , Yuxiang Li

Quantum algorithms require accurate representations of electronic states on a quantum device, yet the approximation of electronic wave functions for strongly correlated systems remains a profound theoretical challenge, with existing methods…

Quantum Physics · Physics 2025-04-29 Dipanjali Halder , Dibyendu Mondal , Rahul Maitra

Quantum computing has shown tremendous promise in addressing complex computational problems, yet its practical realization is hindered by the limited availability of qubits for computation. Recent advancements in quantum hardware have…

Quantum Physics · Physics 2023-11-22 Kun Fang , Munan Zhang , Ruqi Shi , Yinan Li

Nuclear quantum phenomena beyond the Born-Oppenheimer approximation are known to play an important role in a growing number of chemical and biological processes. While there exists no unique consensus on a rigorous and efficient…

Simulating large electronic networks with vibrational environments remains a fundamental challenge due to the long lifetimes of electronic-vibrational (vibronic) excitations on the picosecond scale. Quantum computers are a promising…

We present QEst, a procedure to systematically generate approximations for quantum circuits to reduce their CNOT gate count. Our approach employs circuit partitioning for scalability with procedures to 1) reduce circuit length using…

Quantum Physics · Physics 2021-08-31 Tirthak Patel , Ed Younis , Costin Iancu , Wibe de Jong , Devesh Tiwari

When modeling the effects of noise on quantum circuits, one often makes the assumption that these effects can be accounted for by individual decoherence events following an otherwise noise-free gate. In this work, we address the validity of…

Quantum Physics · Physics 2023-12-19 Keith R. Fratus , Juha Leppäkangas , Michael Marthaler , Jan-Michael Reiner

We study the problem of compilation of quantum algorithms into optimized physical-level circuits executable in a quantum information processing (QIP) experiment based on trapped atomic ions. We report a complete strategy: starting with an…

Quantum Physics · Physics 2017-02-22 Dmitri Maslov

Realizing a conceptual quantum algorithm on an actual physical device necessitates the algorithm's quantum circuit description to undergo certain transformations in order to adhere to all constraints imposed by the hardware. In this regard,…

Quantum Physics · Physics 2023-01-11 Lukas Burgholzer , Rudy Raymond , Robert Wille

Quantum computers are special purpose machines that are expected to be particularly useful in simulating strongly correlated chemical systems. The quantum computer excels at treating a moderate number of orbitals within an active space in a…

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