Related papers: A Multi-granularity Concept Sparse Activation and …

In a complex disease such as tuberculosis, the evidence for the disease and its evolution may be present in multiple modalities such as clinical, genomic, or imaging data. Effective patient-tailored outcome prediction and therapeutic…

Effective mental health counseling is a complex, theory-driven process requiring the simultaneous integration of psychological frameworks, real-time distress signals, and strategic intervention planning. This level of clinical reasoning is…

In precision medicine, quantitative multi-omic features, topological context, and textual biological knowledge play vital roles in identifying disease-critical signaling pathways and targets. Existing pipelines capture only part of…

A multilingual collection may contain useful knowledge in other languages to supplement and correct the facts in the original language for Retrieval-Augmented Generation (RAG). However, the vanilla approach that simply concatenates multiple…

Building upon the standard graph-based Retrieval-Augmented Generation (RAG), the introduction of heterogeneous graphs and hypergraphs aims to enrich retrieval and generation by leveraging the relationships between multiple entities through…

Complex scientific questions often entail multiple intents, such as identifying gene mutations and linking them to related diseases. These tasks require evidence from diverse sources and multi-hop reasoning, while conventional…

In Textual question answering (TQA) systems, complex questions often require retrieving multiple textual fact chains with multiple reasoning steps. While existing benchmarks are limited to single-chain or single-hop retrieval scenarios. In…

Graph-based retrieval-augmented generation (RAG) enriches large language models (LLMs) with external knowledge for long-context understanding and multi-hop reasoning, but existing methods face a granularity dilemma: fine-grained…

While large language models hold promise for complex medical applications, their development is hindered by the scarcity of high-quality reasoning data. To address this issue, existing approaches typically distill chain-of-thought reasoning…

Statistical learning with a large number of rare binary features is commonly encountered in analyzing electronic health records (EHR) data, especially in the modeling of disease onset with prior medical diagnoses and procedures. Dealing…

Graph Retrieval-Augmented Generation (GRAG or Graph RAG) architectures aim to enhance language understanding and generation by leveraging external knowledge. However, effectively capturing and integrating the rich semantic information…

We propose DeepRAG, a novel framework that integrates DeepSeek hierarchical question decomposition capabilities with RAG Gym unified retrieval-augmented generation optimization using process level supervision. Targeting the challenging…

In this paper, we consider the problem of disease diagnosis. Unlike the conventional learning paradigm that treats labels independently, we propose a knowledge-enhanced framework, that enables training visual representation with the…

While large language models are capable diagnostic tools, the impact of multi-agent topology on diagnostic accuracy remains underexplored. This study evaluates four agent topologies, Control (single agent), Hierarchical, Adversarial, and…

Predicting the bioactivity of a ligand is one of the hardest and most important challenges in computer-aided drug discovery. Despite years of data collection and curation efforts by research organizations worldwide, bioactivity data remains…

With the growing imbalance between limited medical resources and escalating demands, AI-based clinical tasks have become paramount. As a sub-domain, medication recommendation aims to amalgamate longitudinal patient history with medical…

Clinical diagnosis is time-consuming, requiring intensive interactions between patients and medical professionals. While large language models (LLMs) could ease the pre-diagnostic workload, their limited domain knowledge hinders effective…

Deep learning has brought significant progress to medical image classification, yet most existing methods still rely on isolated visual evidence and cannot effectively leverage similar cases or external knowledge. In clinical practice,…

Amid growing global mental health concerns, particularly among vulnerable groups, natural language processing offers a tremendous potential for early detection and intervention of people's mental disorders via analyzing their postings and…

Large pretrained language models and neural reasoning systems have advanced many natural language tasks, yet they remain challenged by knowledge-intensive queries that require precise, structured multi-hop inference. Knowledge graphs…