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Spatial transcriptomics (ST) measures mRNA expression while preserving spatial organization, but multi-slice analysis faces two coupled difficulties: large non-rigid deformations across slices and inter-slice batch effects when alignment…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Bonian Han , Cong Qi , Przemyslaw Musialski , Zhi Wei

3D Transformers have achieved great success in point cloud understanding and representation. However, there is still considerable scope for further development in effective and efficient Transformers for large-scale LiDAR point cloud scene…

Computer Vision and Pattern Recognition · Computer Science 2024-12-30 Dening Lu , Jun Zhou , Kyle Gao , Linlin Xu , Jonathan Li

Segmentation of ischemic stroke and intracranial hemorrhage on computed tomography is essential for investigation and treatment of stroke. In this paper, we modified the U-Net CNN architecture for the stroke identification problem using…

Image and Video Processing · Electrical Eng. & Systems 2020-04-01 Manvel Avetisian , Vladimir Kokh , Alex Tuzhilin , Dmitry Umerenkov

Clinical magnetic-resonance (MR) protocols generate many T1 and T2 sequences whose appearance differs more than the acquisition sites that produce them. Existing domain-generalization benchmarks focus almost on cross-center shifts and…

Image and Video Processing · Electrical Eng. & Systems 2025-08-01 Zheyuan Zhang , Linkai Peng , Wanying Dou , Cuiling Sun , Halil Ertugrul Aktas , Andrea M. Bejar , Elif Keles , Gorkem Durak , Ulas Bagci

Accurate segmentation of critical anatomical structures is at the core of medical image analysis. The main bottleneck lies in gathering the requisite expert-labeled image annotations in a scalable manner. Methods that permit to produce…

Computer Vision and Pattern Recognition · Computer Science 2020-07-09 Yuhang Lu , Weijian Li , Kang Zheng , Yirui Wang , Adam P. Harrison , Chihung Lin , Song Wang , Jing Xiao , Le Lu , Chang-Fu Kuo , Shun Miao

Precise ischemic lesion segmentation plays an essential role in improving diagnosis and treatment planning for ischemic stroke, one of the prevalent diseases with the highest mortality rate. While numerous deep neural network approaches…

Image and Video Processing · Electrical Eng. & Systems 2023-12-06 Luca Tomasetti , Stine Hansen , Mahdieh Khanmohammadi , Kjersti Engan , Liv Jorunn Høllesli , Kathinka Dæhli Kurz , Michael Kampffmeyer

The development of automatic segmentation techniques for medical imaging tasks requires assessment metrics to fairly judge and rank such approaches on benchmarks. The Dice Similarity Coefficient (DSC) is a popular choice for comparing the…

Image and Video Processing · Electrical Eng. & Systems 2023-02-13 Vatsal Raina , Nataliia Molchanova , Mara Graziani , Andrey Malinin , Henning Muller , Meritxell Bach Cuadra , Mark Gales

Although the International Classification of Diseases (ICD) has been adopted worldwide, manually assigning ICD codes to clinical text is time-consuming, error-prone, and expensive, motivating the development of automated approaches. This…

Computation and Language · Computer Science 2024-02-06 Gonçalo Gomes , Isabel Coutinho , Bruno Martins

In the field of medical image segmentation, challenges such as indistinct lesion features, ambiguous boundaries,and multi-scale characteristics have long revailed. This paper proposes an improved method named Intensity-Spatial Dual Masked…

Image and Video Processing · Electrical Eng. & Systems 2025-02-17 Yuexing Ding , Jun Wang , Hongbing Lyu

Coronary artery disease (CAD), one of the leading causes of mortality worldwide, necessitates effective risk assessment strategies, with coronary artery calcium (CAC) scoring via computed tomography (CT) being a key method for prevention.…

Image and Video Processing · Electrical Eng. & Systems 2026-02-11 Mahmut S. Gokmen , Caner Ozcan , Moneera N. Haque , Steve W. Leung , C. Seth Parker , W. Brent Seales , Cody Bumgardner

Volumetric lesion segmentation from computed tomography (CT) images is a powerful means to precisely assess multiple time-point lesion/tumor changes. However, because manual 3D segmentation is prohibitively time consuming, current practices…

Computer Vision and Pattern Recognition · Computer Science 2018-07-04 Jinzheng Cai , Youbao Tang , Le Lu , Adam P. Harrison , Ke Yan , Jing Xiao , Lin Yang , Ronald M. Summers

We aim to detect pancreatic ductal adenocarcinoma (PDAC) in abdominal CT scans, which sheds light on early diagnosis of pancreatic cancer. This is a 3D volume classification task with little training data. We propose a two-stage framework,…

Computer Vision and Pattern Recognition · Computer Science 2019-08-22 Fengze Liu , Lingxi Xie , Yingda Xia , Elliot K. Fishman , Alan L. Yuille

Prostate specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT) imaging provides a tremendously exciting frontier in visualization of prostate cancer (PCa) metastatic lesions. However, accurate…

Medical Physics · Physics 2024-12-05 Amirhosein Toosi , Sara Harsini , François Bénard , Carlos Uribe , Arman Rahmim

Automatic pancreas segmentation is fundamental to abdominal MRI analysis, yet deep learning models trained on one MRI sequence often fail catastrophically when applied to another-a challenge that has received little systematic…

Aortic shape analysis plays a key role in cardiovascular diagnostics, treatment planning, and understanding disease progression. We present a robust, fully automated pipeline for aortic shape analysis from cardiac MRI, combining deep…

Tissues and Organs · Quantitative Biology 2025-09-15 Nairouz Shehata , Amr Elsawy , Mohamed Nagy , Muhammad ElMahdy , Mariam Ali , Soha Romeih , Heba Aguib , Magdi Yacoub , Ben Glocker

Dynamic contrast-enhanced (DCE) cardiac magnetic resonance imaging (CMRI) is a widely used modality for diagnosing myocardial blood flow (perfusion) abnormalities. During a typical free-breathing DCE-CMRI scan, close to 300 time-resolved…

Image and Video Processing · Electrical Eng. & Systems 2023-11-14 Dilek M. Yalcinkaya , Khalid Youssef , Bobak Heydari , Orlando Simonetti , Rohan Dharmakumar , Subha Raman , Behzad Sharif

Blood vessel segmentation is a core task in medical image analysis for the care of vascular diseases and surgical planning, yet the challenges of providing expert vascular annotations pose a major obstacle for the progress of related deep…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Erin Rainville , Melissa Ananian , Tristan Mirolla , Hassan Rivaz , Yiming Xiao

Deploying high-performing 3D medical image segmenters (e.g., nnU-Net) is often limited by memory footprint and inference latency. Compression is therefore necessary, but compact 3D encoders tend to lose fine structural cues (small lesions…

Computer Vision and Pattern Recognition · Computer Science 2026-05-27 Mengchen Fan , Baocheng Geng , Xi Xiao , Tianyang Wang , Siyuan Mei , Pulin Che , Xiaoqian Jiang , Qizhen Lan

Stroke poses an immense public health burden and remains among the primary causes of death and disability worldwide. Emergent therapy is often precluded by late or indeterminate times of onset before initial clinical presentation. Rapid,…

Medical Physics · Physics 2021-04-16 Leeor Alon , Seena Dehkharghani

Accurate segmentation of the pelvic CTs is crucial for the clinical diagnosis of pelvic bone diseases and for planning patient-specific hip surgeries. With the emergence and advancements of deep learning for digital healthcare, several…

Image and Video Processing · Electrical Eng. & Systems 2021-01-28 Prabhakara Subramanya Jois , Aniketh Manjunath , Thomas Fevens