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Advances in bio-technology have made available massive amounts of functional, structural and genomic data for many biological sequences. This increased availability of heterogeneous biological data has resulted in biological applications…

Computational Engineering, Finance, and Science · Computer Science 2013-02-26 Srikrishnan Divakaran , Arpit Mithal , Namit Jain

We introduce a consistent estimator for the homology (an algebraic structure representing connected components and cycles) of level sets of both density and regression functions. Our method is based on kernel estimation. We apply this…

Statistics Theory · Mathematics 2016-09-30 Omer Bobrowski , Sayan Mukherjee , Jonathan E. Taylor

Test Case Selection (TCS) aims to select a subset of the test suite to run for regression testing. The selection is typically based on past coverage and execution cost data. Researchers have successfully used multi-objective evolutionary…

Software Engineering · Computer Science 2021-07-21 Mitchell Olsthoorn , Annibale Panichella

This work is dedicated to the topological analysis of complex transitional networks for dynamic state detection. Transitional networks are formed from time series data and they leverage graph theory tools to reveal information about the…

Machine Learning · Statistics 2023-08-08 Audun D. Myers , Max M. Chumley , Firas A. Khasawneh , Elizabeth Munch

Scene graph generation aims to produce structured representations for images, which requires to understand the relations between objects. Due to the continuous nature of deep neural networks, the prediction of scene graphs is divided into…

Computer Vision and Pattern Recognition · Computer Science 2020-08-13 Meng Wei , Chun Yuan , Xiaoyu Yue , Kuo Zhong

A new method for the Automated Protein Structure Analysis (APSA) is derived, which simplifies the protein backbone to a smooth curve in 3-dimensional space. For the purpose of obtaining this smooth line each amino acid is represented by its…

Quantitative Methods · Quantitative Biology 2008-11-24 Sushilee Raganathan , Dmitry Izotov , Elfi Kraka , Dieter Cremer

Musical genre's classification has been a relevant research topic. The association between music and genres is fundamental for the media industry, which manages musical recommendation systems, and for music streaming services, which may…

Audio and Speech Processing · Electrical Eng. & Systems 2021-10-12 Matheus Henrique Pimenta-Zanon , Glaucia Maria Bressan , Fabrício Martins Lopes

Genome sequence analysis plays a pivotal role in enabling many medical and scientific advancements in personalized medicine, outbreak tracing, and forensics. However, the analysis of genome sequencing data is currently bottlenecked by the…

Hardware Architecture · Computer Science 2021-11-04 Damla Senol Cali

Deep learning methods have demonstrated outstanding performances on classification and regression tasks on homogeneous data types (e.g., image, audio, and text data). However, tabular data still pose a challenge, with classic machine…

Machine Learning · Computer Science 2023-11-15 Antonio Briola , Yuanrong Wang , Silvia Bartolucci , Tomaso Aste

Connectionist approaches to machine learning, \emph{i.e.} neural networks, are enjoying a considerable vogue right now. However, these methods require large volumes of data and produce models that are uninterpretable to humans. An…

Artificial Intelligence · Computer Science 2025-05-06 Nolan P Shaw , P Michael Furlong , Britt Anderson , Jeff Orchard

The overwhelming presence of categorical/sequential data in diverse domains emphasizes the importance of sequence mining. The challenging nature of sequences proves the need for continuing research to find a more accurate and faster…

Machine Learning · Computer Science 2022-04-26 Hadi Jahanshahi , Mustafa Gokce Baydogan

Computational topologists recently developed a method, called persistent homology to analyze data presented in terms of similarity or dissimilarity. Indeed, persistent homology studies the evolution of topological features in terms of a…

Quantitative Methods · Quantitative Biology 2017-08-01 Pavel Petrov , Stephen T Rush , Zhichun Zhai , Christine H Lee , Peter T Kim , Giseon Heo

The prevalent approach to sequence to sequence learning maps an input sequence to a variable length output sequence via recurrent neural networks. We introduce an architecture based entirely on convolutional neural networks. Compared to…

Computation and Language · Computer Science 2017-07-26 Jonas Gehring , Michael Auli , David Grangier , Denis Yarats , Yann N. Dauphin

Genomic (DNA) sequences encode an enormous amount of information for gene regulation and protein synthesis. Similar to natural language models, researchers have proposed foundation models in genomics to learn generalizable features from…

Spatial transcriptomics is an emerging field that enables the identification of functional regions based on the spatial distribution of gene expression. Integrating this functional information present in transcriptomic data with structural…

Computer Vision and Pattern Recognition · Computer Science 2025-11-13 Shanaka Liyanaarachchi , Chathurya Wijethunga , Shihab Aaqil Ahamed , Akthas Absar , Ranga Rodrigo

Genes carry the instructions for making proteins that are found in a cell as a specific sequence of nucleotides that are found in DNA molecules. But, the regions of these genes that code for proteins may occupy only a small region of the…

Computational Engineering, Finance, and Science · Computer Science 2014-01-28 Pokkuluri Kiran Sree , Inampudi Ramesh Babu

Topology identification and inference of processes evolving over graphs arise in timely applications involving brain, transportation, financial, power, as well as social and information networks. This chapter provides an overview of graph…

Signal Processing · Electrical Eng. & Systems 2025-12-12 Gonzalo Mateos , Yanning Shen , Georgios B. Giannakis , Ananthram Swami

A PCA based sequence-to-vector (seq2vec) dimension reduction method for the text classification problem, called the tree-structured multi-stage principal component analysis (TMPCA) is presented in this paper. Theoretical analysis and…

Computation and Language · Computer Science 2018-10-12 Yuanhang Su , Ruiyuan Lin , C. -C. Jay Kuo

We introduce graphcodes, a novel multi-scale summary of the topological properties of a dataset that is based on the well-established theory of persistent homology. Graphcodes handle datasets that are filtered along two real-valued scale…

Algebraic Topology · Mathematics 2024-05-24 Michael Kerber , Florian Russold

Topological data analysis (TDA) is a rising field in the intersection of mathematics, statistics, and computer science/data science. The cornerstone of TDA is persistent homology, which produces a summary of topological information called a…

Computational Geometry · Computer Science 2022-05-24 Yu-Min Chung , Michael Hull , Austin Lawson , Neil Pritchard