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Continuing advances in Large Language Models (LLMs) in artificial intelligence offer important capacities in intuitively accessing and using medical knowledge in many contexts, including education and training as well as assessment and…

Computation and Language · Computer Science 2024-08-01 Roma Shusterman , Allison C. Waters , Shannon O`Neill , Phan Luu , Don M. Tucker

Recent advances in Large Language Models (LLMs) have achieved remarkable breakthroughs in understanding and responding to user intents. However, their performance lag behind general use cases in some expertise domains, such as Chinese…

Computation and Language · Computer Science 2023-12-29 Songhua Yang , Hanjie Zhao , Senbin Zhu , Guangyu Zhou , Hongfei Xu , Yuxiang Jia , Hongying Zan

Patient matching is the process of linking patients to appropriate clinical trials by accurately identifying and matching their medical records with trial eligibility criteria. We propose LLM-Match, a novel framework for patient matching…

Computation and Language · Computer Science 2025-03-26 Xiaodi Li , Shaika Chowdhury , Chung Il Wi , Maria Vassilaki , Xiaoke Liu , Terence T Sio , Owen Garrick , Young J Juhn , James R Cerhan , Cui Tao , Nansu Zong

Efficient patient-doctor interaction is among the key factors for a successful disease diagnosis. During the conversation, the doctor could query complementary diagnostic information, such as the patient's symptoms, previous surgery, and…

Computation and Language · Computer Science 2024-10-08 Xueshen Li , Xinlong Hou , Nirupama Ravi , Ziyi Huang , Yu Gan

Mental disorders are highly prevalent worldwide, but the shortage of psychiatrists and the inherent subjectivity of interview-based diagnosis create substantial barriers to timely and consistent mental-health assessment. Progress in…

Multiagent Systems · Computer Science 2026-02-12 Shihao Xu , Tiancheng Zhou , Jiatong Ma , Yanli Ding , Yiming Yan , Ming Xiao , Guoyi Li , Haiyang Geng , Yunyun Han , Jianhua Chen , Yafeng Deng

Large language models (LLMs), due to their advanced natural language capabilities, have seen significant success in applications where the user interface is usually a conversational artificial intelligence (AI) agent and engages the user…

Computation and Language · Computer Science 2025-03-10 Fei Wei , Yaliang Li , Bolin Ding

At the heart of medicine lies the physician-patient dialogue, where skillful history-taking paves the way for accurate diagnosis, effective management, and enduring trust. Artificial Intelligence (AI) systems capable of diagnostic dialogue…

Recent advances in large language models (LLMs) have accelerated the development of conversational agents capable of generating human-like responses. Since psychiatric assessments typically involve complex conversational interactions…

Computation and Language · Computer Science 2025-01-06 Jingoo Lee , Kyungho Lim , Young-Chul Jung , Byung-Hoon Kim

Conversational diagnosis requires multi-turn history-taking, where an agent asks clarifying questions to refine differential diagnoses under incomplete information. Existing approaches often rely on the parametric knowledge of a model or…

Artificial Intelligence · Computer Science 2026-02-04 Jeongmoon Won , Seungwon Kook , Yohan Jo

The increasing complexity of clinical decision-making, alongside the rapid expansion of electronic health records (EHR), presents both opportunities and challenges for delivering data-informed care. This paper proposes a clinical decision…

Artificial Intelligence · Computer Science 2025-10-03 Leon Garza , Anantaa Kotal , Michael A. Grasso , Emre Umucu

Background: Large language models (LLMs) such as OpenAI's GPT-4 or Google's PaLM 2 are proposed as viable diagnostic support tools or even spoken of as replacements for "curbside consults". However, even LLMs specifically trained on medical…

Artificial Intelligence · Computer Science 2024-10-21 Gioele Barabucci , Victor Shia , Eugene Chu , Benjamin Harack , Nathan Fu

The proliferation of Large Language Models (LLMs) in medicine has enabled impressive capabilities, yet a critical gap remains in their ability to perform systematic, transparent, and verifiable reasoning, a cornerstone of clinical practice.…

Computation and Language · Computer Science 2025-08-04 Wenxuan Wang , Zizhan Ma , Meidan Ding , Shiyi Zheng , Shengyuan Liu , Jie Liu , Jiaming Ji , Wenting Chen , Xiang Li , Linlin Shen , Yixuan Yuan

Background: Large Language Models (LLMs) are transforming artificial intelligence applications in healthcare due to their ability to understand, generate, and summarize complex medical text. They offer valuable support to clinicians,…

Computation and Language · Computer Science 2026-04-14 Subin Santhosh , Farwa Abbas , Hussain Ahmad , Claudia Szabo

Large language models (LLMs) are increasingly attracting the attention of healthcare professionals for their potential to assist in diagnostic assessments, which could alleviate the strain on the healthcare system caused by a high patient…

Computation and Language · Computer Science 2025-01-03 Kaushik Roy , Harshul Surana , Darssan Eswaramoorthi , Yuxin Zi , Vedant Palit , Ritvik Garimella , Amit Sheth

With the rapid growth of large language models (LLMs) and vision-language models (VLMs) in medicine, simply integrating clinical text and medical imaging does not guarantee reliable reasoning. Existing multimodal models often produce…

Artificial Intelligence · Computer Science 2025-12-29 Zelin Zang , Wenyi Gu , Siqi Ma , Dan Yang , Yue Shen , Zhu Zhang , Guohui Fan , Wing-Kuen Ling , Fuji Yang

With the advancement of large language models, many dialogue systems are now capable of providing reasonable and informative responses to patients' medical conditions. However, when patients consult their doctor, they may experience…

Computation and Language · Computer Science 2025-06-17 Shang-Chi Tsai , Yun-Nung Chen

Doctors and patients alike increasingly use Large Language Models (LLMs) to diagnose clinical cases. However, unlike domains such as math or coding, where correctness can be objectively defined by the final answer, medical diagnosis…

Computation and Language · Computer Science 2025-05-21 Kevin Wu , Eric Wu , Rahul Thapa , Kevin Wei , Angela Zhang , Arvind Suresh , Jacqueline J. Tao , Min Woo Sun , Alejandro Lozano , James Zou

Current medical AI systems often fail to replicate real-world clinical reasoning, as they are predominantly trained and evaluated on static text and question-answer tasks. These tuning methods and benchmarks overlook critical aspects like…

Computation and Language · Computer Science 2026-02-24 Zijie Liu , Xinyu Zhao , Jie Peng , Zhuangdi Zhu , Qingyu Chen , Kaidi Xu , Xia Hu , Tianlong Chen

Large language models (LLMs) show promise for healthcare question answering, but clinical use is limited by weak verification, insufficient evidence grounding, and unreliable confidence signalling. We propose a multi-agent medical QA…

Computation and Language · Computer Science 2026-02-17 Naeimeh Nourmohammadi , Md Meem Hossain , The Anh Han , Safina Showkat Ara , Zia Ush Shamszaman

Diagnosing student problem behaviors requires teachers to synthesize multifaceted information, identify behavioral categories, and plan intervention strategies. Although fine-tuned large language models (LLMs) can support this process…

Computation and Language · Computer Science 2026-04-27 Zhilin Fan , Deliang Wang , Penghe Chen , Yu Lu