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At the macroscale, the brain operates as a network of interconnected neuronal populations, which display rhythmic dynamics that support interareal communication. Understanding how stimulation of a particular brain area impacts such…

Neurons and Cognition · Quantitative Biology 2020-11-12 Lia Papadopoulos , Christopher W. Lynn , Demian Battaglia , Danielle S. Bassett

Population-based methods are often used to solve multimodal optimization problems. By combining niching or clustering strategy, the state-of-the-art approaches generally divide the population into several subpopulations to find multiple…

Neural and Evolutionary Computing · Computer Science 2021-05-28 Jian Yang , Yuhui Shi

The ability to modulate brain states using targeted stimulation is increasingly being employed to treat neurological disorders and to enhance human performance. Despite the growing interest in brain stimulation as a form of neuromodulation,…

Neurons and Cognition · Quantitative Biology 2016-01-07 Sarah Feldt Muldoon , Fabio Pasqualetti , Shi Gu , Matthew Cieslak , Scott T. Grafton , Jean M. Vettel , Danielle S. Bassett

Neurostimulation technologies have seen a recent surge in interest from the neuroscience and controls communities alike due to their proven potential to treat conditions such as Parkinson's Disease, and depression. The provided stimulation…

Systems and Control · Electrical Eng. & Systems 2023-01-03 Gagan Acharya , Sebastian F. Ruf , Erfan Nozari

Today's deep learning architectures are primarily based on perceptron models, which do not capture the oscillatory dynamics characteristic of biological neurons. Although oscillatory systems have recently gained attention for their closer…

Machine Learning · Computer Science 2025-10-14 Zhongju Yuan , Geraint Wiggins , Dick Botteldooren

Higher brain function relies upon the ability to flexibly integrate information across specialized communities of brain regions, however it is unclear how this mechanism manifests over time. In this study, we use time-resolved network…

Human brain dynamics can be profitably viewed through the lens of statistical mechanics, where neurophysiological activity evolves around and between local attractors representing preferred mental states. Many physically-inspired models of…

Neurons and Cognition · Quantitative Biology 2016-09-06 Arian Ashourvan , Shi Gu , Marcelo G. Mattar , Jean M. Vettel , Danielle S. Bassett

The decoding of brain signals recorded via, e.g., an electroencephalogram, using machine learning is key to brain-computer interfaces (BCIs). Stimulation parameters or other experimental settings of the BCI protocol typically are chosen…

Neurons and Cognition · Quantitative Biology 2021-09-14 Jan Sosulski , David Hübner , Aaron Klein , Michael Tangermann

We apply the framework of optimal nonlinear control to steer the dynamics of a whole-brain network of FitzHugh-Nagumo oscillators. Its nodes correspond to the cortical areas of an atlas-based segmentation of the human cerebral cortex, and…

Neurons and Cognition · Quantitative Biology 2021-09-08 Teresa Chouzouris , Nicolas Roth , Caglar Cakan , Klaus Obermayer

The relationship between brain structure and function has been probed using a variety of approaches, but how the underlying structural connectivity of the human brain drives behavior is far from understood. To investigate the effect of…

Neurons and Cognition · Quantitative Biology 2018-11-15 Kanika Bansal , John D. Medaglia , Danielle S. Bassett , Jean M. Vettel , Sarah F. Muldoon

Objective: A major challenge in designing closed-loop brain-computer interfaces is finding optimal stimulation patterns as a function of ongoing neural activity for different subjects and objectives. Approach: To achieve goal-directed…

Neurons and Cognition · Quantitative Biology 2023-03-22 Matthew J. Bryan , Linxing Preston Jiang , Rajesh P N Rao

Concept-selective regions within the human cerebral cortex exhibit significant activation in response to specific visual stimuli associated with particular concepts. Precisely localizing these regions stands as a crucial long-term goal in…

Neurons and Cognition · Quantitative Biology 2025-03-05 Guangyin Bao , Qi Zhang , Zixuan Gong , Zhuojia Wu , Duoqian Miao

Elements of neural networks, both biological and artificial, can be described by their selectivity for specific cognitive features. Understanding these features is important for understanding the inner workings of neural networks. For a…

Neural and Evolutionary Computing · Computer Science 2026-04-28 Nikita Pospelov , Andrei Chertkov , Maxim Beketov , Ivan Oseledets , Konstantin Anokhin

Brain stimulation is a core method in neuroscience. Numerous non-invasive brain stimulation (NIBS) techniques are currently in use in basic and clinical research, and recent advances promise the ability to non-invasively access deep brain…

Neurons and Cognition · Quantitative Biology 2021-11-02 Sebastian J Lehmann , Brian D Corneil

Neuroscientists have enjoyed much success in understanding brain functions by constructing brain connectivity networks using data collected under highly controlled experimental settings. However, these experimental settings bear little…

Machine Learning · Statistics 2019-06-24 Kean Ming Tan , Junwei Lu , Tong Zhang , Han Liu

The models in statistical physics such as an Ising model offer a convenient way to characterize stationary activity of neural populations. Such stationary activity of neurons may be expected for recordings from in vitro slices or…

Neurons and Cognition · Quantitative Biology 2017-05-05 Christian Donner , Klaus Obermayer , Hideaki Shimazaki

This workshop explores the interface between cognitive neuroscience and recent advances in AI fields that aim to reproduce human performance such as natural language processing and computer vision, and specifically deep learning approaches…

Training large language models (LLMs) is constrained by memory requirements, with activations accounting for a substantial fraction of the total footprint. Existing approaches reduce memory using low-rank weight parameterizations or…

Machine Learning · Computer Science 2026-04-13 Sakshi Choudhary , Utkarsh Saxena , Kaushik Roy

The mammalian brain is a metabolically expensive device, and evolutionary pressures have presumably driven it to make productive use of its resources. For sensory areas, this concept has been expressed more formally as an optimality…

Neurons and Cognition · Quantitative Biology 2016-03-02 Deep Ganguli , Eero P. Simoncelli

Efficient complex systems have a modular structure, but modularity does not guarantee robustness, because efficiency also requires an ingenious interplay of the interacting modular components. The human brain is the elemental paradigm of an…

Neurons and Cognition · Quantitative Biology 2022-06-08 Flaviano Morone , Kevin Roth , Byungjoon Min , H. Eugene Stanley , Hernán A. Makse
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