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One outcome of interspecific hybridization and subsequent effects of evolutionary forces is introgression, which is the integration of genetic material from one species into the genome of an individual in another species. The evolution of…

Populations and Evolution · Quantitative Biology 2015-06-17 Kevin J. Liu , Jingxuan Dai , Kathy Truong , Ying Song , Michael H. Kohn , Luay Nakhleh

The evolutionary significance of hybridization and subsequent introgression has long been appreciated, but evaluation of the genome-wide effects of these phenomena has only recently become possible. Crop-wild study systems represent ideal…

Populations and Evolution · Quantitative Biology 2013-07-30 Matthew B. Hufford , Pesach Lubinksy , Tanja Pyhäjärvi , Michael T. Devengenzo , Norman C. Ellstrand , Jeffrey Ross-Ibarra

As whole genomes become widely available, maximum likelihood and Bayesian phylogenetic methods are demonstrating their limits in meeting the escalating computational demands. Conversely, distance-based phylogenetic methods are efficient,…

Populations and Evolution · Quantitative Biology 2025-02-07 Matthew J. Penn , Neil Scheidwasser , Mark P. Khurana , Christl A. Donnelly , David A. Duchêne , Samir Bhatt

Significant phylogenetic codivergence between plant or animal hosts ($H$) and their symbionts or parasites ($P$) indicate the importance of their interactions on evolutionary time scales. However, valid and realistic methods to test for…

Populations and Evolution · Quantitative Biology 2008-08-28 Chris L. Schardl , Kelly D. Craven , Adam Lindstrom , Skyler Speakman , Arnold Stromberg , Ruriko Yoshida

Complete genome sequences contain valuable information about natural selection, but extracting this information for short, widely scattered noncoding elements remains a challenging problem. Here we introduce a new computational method for…

Genomics · Quantitative Biology 2015-03-19 Ilan Gronau , Leonardo Arbiza , Jaaved Mohammed , Adam Siepel

We report on a genome-wide scan for introgression in the house mouse (Mus musculus domesticus) involving the Algerian mouse (Mus spretus), using samples from the ranges of sympatry and allopatry in Africa and Europe. Our analysis reveals…

Populations and Evolution · Quantitative Biology 2014-09-22 Kevin J. Liu , Ethan Steinberg , Alexander Yozzo , Ying Song , Michael H. Kohn , Luay Nakhleh

Introgression is an evolutionary process in which genes or other types of genetic material are introduced into a genome. It is an important evolutionary process that can, for example, play a fundamental role in speciation. Recently the…

Combinatorics · Mathematics 2020-06-26 K. T. Huber , V. Moulton , G. E. Scholz

The recA/RAD51 gene family encodes a diverse set of recombinase proteins that effect homologous recombination, DNA-repair, and genome stability. The recA gene family is expressed in almost all species of Eubacteria, Archaea, and Eukaryotes,…

Breeding by introgressive hybridization is a pivotal strategy to broaden the genetic basis of crops. Usually, the desired traits are monitored in consecutive crossing generations by marker-assisted selection, but their analyses fail in…

Motivation: While the majority of gene histories found in a clade of organisms are expected to be generated by a common process (e.g. the coalescent process), it is well-known that numerous other coexisting processes (e.g. horizontal gene…

Genomics · Quantitative Biology 2014-04-23 Grady Weyenberg , Peter Huggins , Christopher Schardl , Daniel K Howe , Ruriko Yoshida

All genes interact with other genes, and their additive effects and epistatic interactions affect an organism's phenotype and fitness. Recent theoretical and empirical work has advanced our understanding of the role of multi-locus…

Populations and Evolution · Quantitative Biology 2020-05-29 I. Satokangas , S. H. Martin , H. Helanterä , J. Saramäki , J. Kulmuni

We provide, on an extensive dataset and using several different distances, confirmation of the hypothesis that CGR patterns are preserved along a genomic DNA sequence, and are different for DNA sequences originating from genomes of…

Genomics · Quantitative Biology 2015-03-11 Rallis Karamichalis , Lila Kari , Stavros Konstantinidis , Steffen Kopecki

Post-implant dosimetry (PID) is an essential step of prostate brachytherapy that utilizes CT to image the prostate and allow the location and dose distribution of the radioactive seeds to be directly related to the actual prostate. However,…

Image and Video Processing · Electrical Eng. & Systems 2019-06-26 Yading Yuan , Ren-Dih Sheu , Luke Fu , Yeh-Chi Lo

Reconstructing the tree of life from molecular sequences is a fundamental problem in computational biology. Modern data sets often contain a large number of genes, which can complicate the reconstruction problem due to the fact that…

Probability · Mathematics 2017-07-21 Constantinos Daskalakis , Sebastien Roch

In this work, we propose a new deep learning model for Genomic Prediction (GP), which involves correlating genotypic data with phenotypic. The genotypes are typically fed as a sequence of characters to the 1D-Convolution Neural Network…

Machine Learning · Computer Science 2026-03-03 Kuldeep Pathak , Kapil Ahuja , Eric de Sturler

Secondary contact between divergent populations or incipient species may result in the exchange and introgression of genomic material. We develop a simple DNA sequence measure, called Gmin, which is designed to identify genomic regions…

Populations and Evolution · Quantitative Biology 2017-02-08 Anthony J. Geneva , Sarah B. Kingan , Daniel Garrigan

The Rosids is one of the largest groups of flowering plants, with 140 families and ~70,000 species. Previous phylogenetic studies of the rosids have primarily utilized organelle genes that likely differ in evolutionary histories from…

Populations and Evolution · Quantitative Biology 2016-07-01 Lei Zhao , Xia Li , Ning Zhang , Shu-Dong Zhang , Ting-Shuang Yi , Hong Ma , Zhen-Hua Guo , De-Zhu Li

Graph-based machine learning methods are useful tools in the identification and prediction of variation in genetic data. In particular, the comprehension of phenotypic effects at the cellular level is an accelerating research area in…

Quantitative Methods · Quantitative Biology 2024-12-06 Nandini Gadhia , Michalis Smyrnakis , Po-Yu Liu , Damer Blake , Melanie Hay , Anh Nguyen , Dominic Richards , Dong Xia , Ritesh Krishna

This work illustrates potentials for recognition within {\em ad hoc} sensor networks if their nodes possess individual inter-related biologically inspired genetic codes. The work takes ideas from natural immune systems protecting organisms…

Cryptography and Security · Computer Science 2009-12-31 Reinert Korsnes , Knut Ovsthus
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