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Deep learning networks are increasingly attracting attention in various fields, including electroencephalography (EEG) signal processing. These models provided comparable performance with that of traditional techniques. At present, however,…

Signal Processing · Electrical Eng. & Systems 2021-07-29 Haoming Zhang , Mingqi Zhao , Chen Wei , Dante Mantini , Zherui Li , Quanying Liu

Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder characterized by progressive cognitive decline and widespread epigenetic dysregulation in the brain. DNA methylation, as a stable yet dynamic epigenetic modification,…

Genomics · Quantitative Biology 2026-01-05 Gang Qu , Guanghao Li , Zhongming Zhao

Electrocardiography (ECG), an electrical measurement which captures cardiac activities, is the gold standard for diagnosing cardiovascular disease (CVD). However, ECG is infeasible for continuous cardiac monitoring due to its requirement…

Signal Processing · Electrical Eng. & Systems 2022-12-06 Ella Lan

Parkinson's disease (PD) is a progressive neurodegenerative disorder that, in addition to directly impairing functional mobility, is frequently associated with vocal impairments such as hypophonia and dysarthria, which typically manifest in…

Foundation models for time series are emerging as powerful general-purpose backbones, yet their potential for domain-specific biomedical signals such as electroencephalography (EEG) remains rather unexplored. In this work, we investigate…

Machine Learning · Computer Science 2025-11-03 Théo Gnassounou , Yessin Moakher , Shifeng Xie , Vasilii Feofanov , Ievgen Redko

Acceleration of machine learning research in healthcare is challenged by lack of large annotated and balanced datasets. Furthermore, dealing with measurement inaccuracies and exploiting unsupervised data are considered to be central to…

Signal Processing · Electrical Eng. & Systems 2019-01-11 Deepta Rajan , David Beymer , Girish Narayan

Epileptic seizure detection from EEG signals remains challenging due to the high dimensionality and nonlinear, potentially stochastic, dynamics of neural activity. In this work, we investigate whether features derived from topological data…

Machine Learning · Computer Science 2026-04-15 Sunia Tanweer , Narayan Puthanmadam Subramaniyam , Firas A. Khasawneh

In conventional machine learning (ML) approaches applied to electroencephalography (EEG), this is often a limited focus, isolating specific brain activities occurring across disparate temporal scales (from transient spikes in milliseconds…

Quantitative Methods · Quantitative Biology 2024-02-06 Jonathan W. Kim , Ahmed Alaa , Danilo Bernardo

A new deep learning-based electroencephalography (EEG) signal analysis framework is proposed. While deep neural networks, specifically convolutional neural networks (CNNs), have gained remarkable attention recently, they still suffer from…

Signal Processing · Electrical Eng. & Systems 2019-08-29 Mojtaba Taherisadr , Mohsen Joneidi , Nazanin Rahnavard

Classification models for electroencephalogram (EEG) data show a large decrease in performance when evaluated on unseen test sub jects. We reduce this performance decrease using new regularization techniques during model training. We…

Machine Learning · Computer Science 2023-10-16 Niklas Smedemark-Margulies , Ye Wang , Toshiaki Koike-Akino , Jing Liu , Kieran Parsons , Yunus Bicer , Deniz Erdogmus

Alzheimer's Disease is a progressive neurological disorder that is one of the most common forms of dementia. It leads to a decline in memory, reasoning ability, and behavior, especially in older people. The cause of Alzheimer's Disease is…

Machine Learning · Computer Science 2025-04-03 Jing Wang , Jun-En Ding , Feng Liu , Elisa Kallioniemi , Shuqiang Wang , Wen-Xiang Tsai , Albert C. Yang

This study introduces a WaveNet-based deep learning model designed to automate the classification of intracranial electroencephalography (iEEG) signals into physiological activity, pathological (epileptic) activity, power-line noise, and…

Machine Learning · Computer Science 2026-01-14 Casper van Laar , Khubaib Ahmed

Electroencephalography (EEG) is widely used in neuroscience and clinical research for analyzing brain activity. While deep learning models such as EEGNet have shown success in decoding EEG signals, they often struggle with data complexity,…

Quantum Physics · Physics 2025-03-05 Chi-Sheng Chen , Samuel Yen-Chi Chen , Huan-Hsin Tseng

Electroencephalography (EEG) is a non-invasive technique for recording brain electrical activity, widely used in brain-computer interface (BCI) and healthcare. Recent EEG foundation models trained on large-scale datasets have shown improved…

Machine Learning · Computer Science 2025-09-29 Yi Ding , Muyun Jiang , Weibang Jiang , Shuailei Zhang , Xinliang Zhou , Chenyu Liu , Shanglin Li , Yong Li , Cuntai Guan

This work investigates the predictive potential of bipolar electroencephalogram (EEG) recordings towards efficient prediction of poor neurological outcomes. A retrospective design using a hybrid deep learning approach is utilized to…

Signal Processing · Electrical Eng. & Systems 2023-10-09 Hemin Ali Qadir , Naimahmed Nesaragi , Per Steiner Halvorsen , Ilangko Balasingham

Clinical electroencephalography is routinely used to evaluate patients with diverse and often overlapping neurological conditions, yet interpretation remains manual, time-intensive, and variable across experts. While automated EEG analysis…

Human-Computer Interaction · Computer Science 2025-12-30 Argha Kamal Samanta , Deepak Mewada , Monalisa Sarma , Debasis Samanta

The Early diagnosis and treatment of depression is essential for effective treatment. Depression, while being one of the most common mental illnesses, is still poorly understood in both research and clinical practice. Among different…

Signal Processing · Electrical Eng. & Systems 2023-03-13 Abdolkarim Saeedi , Arash Maghsoudi , Fereidoun Nowshiravan Rahatabad

This work presents xEEGNet, a novel, compact, and explainable neural network for EEG data analysis. It is fully interpretable and reduces overfitting through major parameter reduction. As an applicative use case, we focused on classifying…

Machine Learning · Computer Science 2025-12-04 Andrea Zanola , Louis Fabrice Tshimanga , Federico Del Pup , Marco Baiesi , Manfredo Atzori

The presence of interictal epileptiform discharges (IEDs) in electroencephalogram (EEG) recordings is a critical biomarker of epilepsy. Even trained neurologists find detecting IEDs difficult, leading many practitioners to turn to machine…

Diagnosing pre-existing heart diseases early in life is important as it helps prevent complications such as pulmonary hypertension, heart rhythm problems, blood clots, heart failure and sudden cardiac arrest. To identify such diseases,…