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Deep learning models have exhibited remarkable efficacy in accurately delineating the prostate for diagnosis and treatment of prostate diseases, but challenges persist in achieving robust generalization across different medical centers.…

Computer Vision and Pattern Recognition · Computer Science 2024-07-08 Zihao Luo , Xiangde Luo , Zijun Gao , Guotai Wang

We hypothesize that anatomical priors can be viable mediums to infuse domain-specific clinical knowledge into state-of-the-art convolutional neural networks (CNN) based on the U-Net architecture. We introduce a probabilistic population…

Image and Video Processing · Electrical Eng. & Systems 2021-09-22 Anindo Saha , Matin Hosseinzadeh , Henkjan Huisman

Semi-supervised learning utilizes insights from unlabeled data to improve model generalization, thereby reducing reliance on large labeled datasets. Most existing studies focus on limited samples and fail to capture the overall data…

Computer Vision and Pattern Recognition · Computer Science 2025-03-13 Xiuzhen Guo , Lianyuan Yu , Ji Shi , Na Lei , Hongxiao Wang

Latent Diffusion Models (LDMs) are generally trained at fixed resolutions, limiting their capability when scaling up to high-resolution images. While training-based approaches address this limitation by training on high-resolution datasets,…

Computer Vision and Pattern Recognition · Computer Science 2025-07-30 Sangmin Han , Jinho Jeong , Jinwoo Kim , Seon Joo Kim

Magnetic Resonance Imaging (MRI) reconstruction is essential in medical diagnostics. As the latest generative models, diffusion models (DMs) have struggled to produce high-fidelity images due to their stochastic nature in image domains.…

Image and Video Processing · Electrical Eng. & Systems 2025-07-01 Lingtong Zhang , Mengdie Song , Xiaohan Hao , Huayu Mai , Bensheng Qiu

Generative models based on deep learning have shown significant potential in medical imaging, particularly for modality transformation and multimodal fusion in MRI-based brain imaging. This study introduces GM-LDM, a novel framework that…

Image and Video Processing · Electrical Eng. & Systems 2025-06-17 Hu Xu , Yang Jingling , Jia Sihan , Bi Yuda , Calhoun Vince

Identifying differentially methylated cytosine-guanine dinucleotide (CpG) sites between benign and tumour samples can assist in understanding disease. However, differential analysis of bounded DNA methylation data often requires data…

Annotation-efficient segmentation of the numerous mitochondria instances from various electron microscopy (EM) images is highly valuable for biological and neuroscience research. Although unsupervised domain adaptation (UDA) methods can…

Computer Vision and Pattern Recognition · Computer Science 2026-05-04 Shan Xiong , Jiabao Chen , Ye Wang , Jialin Peng

Quality of deep convolutional neural network predictions strongly depends on the size of the training dataset and the quality of the annotations. Creating annotations, especially for 3D medical image segmentation, is time-consuming and…

Image and Video Processing · Electrical Eng. & Systems 2023-05-11 Matin Hosseinzadeh , Anindo Saha , Joeran Bosma , Henkjan Huisman

Prostate cancer (PCa) was the most frequently diagnosed cancer among American men in 2023. The histological grading of biopsies is essential for diagnosis, and various deep learning-based solutions have been developed to assist with this…

Image and Video Processing · Electrical Eng. & Systems 2024-09-16 Ekaterina Redekop , Mara Pleasure , Zichen Wang , Anthony Sisk , Yang Zong , Kimberly Flores , William Speier , Corey W. Arnold

Continual Test-Time Adaptation (CTTA) aims to adapt a pre-trained model to a sequence of target domains during the test phase without accessing the source data. To adapt to unlabeled data from unknown domains, existing methods rely on…

Machine Learning · Computer Science 2024-07-15 Jiayao Tan , Fan Lyu , Chenggong Ni , Tingliang Feng , Fuyuan Hu , Zhang Zhang , Shaochuang Zhao , Liang Wang

General-purpose large language models (LLMs) are increasingly deployed in verticals such as telecommunications, where adaptation is hindered by scarce, low-information-density corpora and tight mobile/edge constraints. We propose Data…

Machine Learning · Computer Science 2025-11-11 Zhicheng Zhou , Jing Li , Suming Qiu , Junjie Huang , Linyuan Qiu , Zhijie Sun

Automated 3D segmentation of prostate lesions from biparametric MRI (bp-MRI) is essential for reliable algorithmic analysis, but achieving high precision remains challenging. Volumetric methods must combine multiple modalities while…

Computer Vision and Pattern Recognition · Computer Science 2026-04-22 Cuiling Sun , Linkai Peng , Adam Murphy , Elif Keles , Hiten D. Patel , Ashley Ross , Frank Miller , Baris Turkbey , Andrea Mia Bejar , Halil Ertugrul Aktas , Gorkem Durak , Ulas Bagci

The need for training data can impede the adoption of novel imaging modalities for learning-based medical image analysis. Domain adaptation methods partially mitigate this problem by translating training data from a related source domain to…

Computer Vision and Pattern Recognition · Computer Science 2021-01-19 Eleni Chiou , Francesco Giganti , Shonit Punwani , Iasonas Kokkinos , Eleftheria Panagiotaki

When the training and test data are from different distributions, domain adaptation is needed to reduce dataset bias to improve the model's generalization ability. Since it is difficult to directly match the cross-domain joint…

Machine Learning · Computer Science 2020-07-28 Chaohui Yu , Jindong Wang , Chang Liu , Tao Qin , Renjun Xu , Wenjie Feng , Yiqiang Chen , Tie-Yan Liu

The domain discrepancy existed between medical images acquired in different situations renders a major hurdle in deploying pre-trained medical image segmentation models for clinical use. Since it is less possible to distribute training data…

Computer Vision and Pattern Recognition · Computer Science 2022-11-22 Shishuai Hu , Zehui Liao , Yong Xia

Biparametric MRI has emerged as an alternative to multiparametric prostate MRI, which eliminates the need for the potential harms to the patient due to the contrast medium. One major issue with biparametric MRI is difficulty to detect…

We focus on the problem of Unsupervised Domain Adaptation (\uda) for breast cancer detection from mammograms (BCDM) problem. Recent advancements have shown that masked image modeling serves as a robust pretext task for UDA. However, when…

Computer Vision and Pattern Recognition · Computer Science 2024-07-10 Tajamul Ashraf , Krithika Rangarajan , Mohit Gambhir , Richa Gabha , Chetan Arora

The scarcity and complexity of voxel-level annotations in 3D medical imaging present significant challenges, particularly due to the domain gap between labeled datasets from well-resourced centers and unlabeled datasets from less-resourced…

Computer Vision and Pattern Recognition · Computer Science 2024-08-13 Haifan Gong , Yitao Wang , Yihan Wang , Jiashun Xiao , Xiang Wan , Haofeng Li

We present a fully automated, anatomically guided deep learning pipeline for prostate cancer (PCa) risk stratification using routine MRI. The pipeline integrates three key components: an nnU-Net module for segmenting the prostate gland and…

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