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Generalized category discovery (GCD) is a pragmatic but underexplored problem, which requires models to automatically cluster and discover novel categories by leveraging the labeled samples from old classes. The challenge is that unlabeled…

Machine Learning · Computer Science 2025-04-08 Shijie Ma , Fei Zhu , Xu-Yao Zhang , Cheng-Lin Liu

Graph neural network (GNN) is a powerful learning approach for graph-based recommender systems. Recently, GNNs integrated with contrastive learning have shown superior performance in recommendation with their data augmentation schemes,…

Information Retrieval · Computer Science 2023-06-16 Xuheng Cai , Chao Huang , Lianghao Xia , Xubin Ren

Image segmentation relies on large annotated datasets, which are expensive and slow to produce. Silver-standard (AI-generated) labels are easier to obtain, but they risk introducing bias. Self-supervised learning, needing only images, has…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Marceau Lafargue-Hauret , Raghav Mehta , Fabio De Sousa Ribeiro , Mélanie Roschewitz , Ben Glocker

Protein-ligand interactions (PLIs) are fundamental to biochemical research and their identification is crucial for estimating biophysical and biochemical properties for rational therapeutic design. Currently, experimental characterization…

Machine Learning · Statistics 2021-12-01 Carter Knutson , Mridula Bontha , Jenna A. Bilbrey , Neeraj Kumar

Protein (receptor)--ligand interaction prediction is a critical component in computer-aided drug design, significantly influencing molecular docking and virtual screening processes. Despite the development of numerous scoring functions in…

Biomolecules · Quantitative Biology 2024-01-22 Haoyu Lin , Shiwei Wang , Jintao Zhu , Yibo Li , Jianfeng Pei , Luhua Lai

To learn target discriminative representations, using pseudo-labels is a simple yet effective approach for unsupervised domain adaptation. However, the existence of false pseudo-labels, which may have a detrimental influence on learning…

Computer Vision and Pattern Recognition · Computer Science 2019-08-02 Jaehoon Choi , Minki Jeong , Taekyung Kim , Changick Kim

Although graph neural networks (GNNs) have achieved impressive achievements in graph classification, they often need abundant task-specific labels, which could be extensively costly to acquire. A credible solution is to explore additional…

Machine Learning · Computer Science 2025-07-15 Nan Yin , Li Shen , Mengzhu Wang , Long Lan , Zeyu Ma , Chong Chen , Xian-Sheng Hua , Xiao Luo

Recently, structure-text contrastive learning has shown promising performance on text-attributed graphs by leveraging the complementary strengths of graph neural networks and language models. However, existing methods typically rely on…

Machine Learning · Computer Science 2026-01-29 Yating Ren , Yikun Ban , Huobin Tan

The embedding of Biomedical Knowledge Graphs (BKGs) generates robust representations, valuable for a variety of artificial intelligence applications, including predicting drug combinations and reasoning disease-drug relationships.…

Databases · Computer Science 2023-10-17 Zhiguang Fan , Yuedong Yang , Mingyuan Xu , Hongming Chen

Contrastive Language-Image Pre-training (CLIP) has achieved success on multiple downstream tasks by aligning image and text modalities. However, the nature of global contrastive learning limits CLIP's ability to comprehend compositional…

Computer Vision and Pattern Recognition · Computer Science 2025-08-27 Xiaoxing Hu , Kaicheng Yang , Jun Wang , Haoran Xu , Ziyong Feng , Yupei Wang

Graph Neural Networks (GNNs) have become powerful tools in modeling graph-structured data in recommender systems. However, real-life recommendation scenarios usually involve heterogeneous relationships (e.g., social-aware user influence,…

Information Retrieval · Computer Science 2023-03-03 Mengru Chen , Chao Huang , Lianghao Xia , Wei Wei , Yong Xu , Ronghua Luo

Deep networks have strong capacities of embedding data into latent representations and finishing following tasks. However, the capacities largely come from high-quality annotated labels, which are expensive to collect. Noisy labels are more…

Computer Vision and Pattern Recognition · Computer Science 2022-03-09 Shikun Li , Xiaobo Xia , Shiming Ge , Tongliang Liu

Graph Convolutional Networks (GCNs) show promising results for semi-supervised learning tasks on graphs, thus become favorable comparing with other approaches. Despite the remarkable success of GCNs, it is difficult to train GCNs with…

Machine Learning · Computer Science 2020-08-14 Xianfeng Tang , Huaxiu Yao , Yiwei Sun , Yiqi Wang , Jiliang Tang , Charu Aggarwal , Prasenjit Mitra , Suhang Wang

Cross-graph Relational Learning (CGRL) refers to the problem of predicting the strengths or labels of multi-relational tuples of heterogeneous object types, through the joint inference over multiple graphs which specify the internal…

Machine Learning · Computer Science 2016-05-09 Hanxiao Liu , Yiming Yang

Contrastive learning (CL) has achieved astonishing progress in computer vision, speech, and natural language processing fields recently with self-supervised learning. However, CL approach to the supervised setting is not fully explored,…

Computation and Language · Computer Science 2022-05-23 Zhenyu Zhang , Yuming Zhao , Meng Chen , Xiaodong He

The recent breakthrough achieved by contrastive learning accelerates the pace for deploying unsupervised training on real-world data applications. However, unlabeled data in reality is commonly imbalanced and shows a long-tail distribution,…

Computer Vision and Pattern Recognition · Computer Science 2021-06-08 Ziyu Jiang , Tianlong Chen , Bobak Mortazavi , Zhangyang Wang

Graph databases (GDBs) enable processing and analysis of unstructured, complex, rich, and usually vast graph datasets. Despite the large significance of GDBs in both academia and industry, little effort has been made into integrating them…

We propose Graph Contrastive Learning (GraphCL), a general framework for learning node representations in a self supervised manner. GraphCL learns node embeddings by maximizing the similarity between the representations of two randomly…

Machine Learning · Computer Science 2020-07-17 Hakim Hafidi , Mounir Ghogho , Philippe Ciblat , Ananthram Swami

Graph Neural Networks (GNNs) have demonstrated promising results on exploiting node representations for many downstream tasks through supervised end-to-end training. To deal with the widespread label scarcity issue in real-world…

Machine Learning · Computer Science 2023-08-02 Cheng Wu , Chaokun Wang , Jingcao Xu , Ziyang Liu , Kai Zheng , Xiaowei Wang , Yang Song , Kun Gai

Research on Graph Structure Learning (GSL) provides key insights for graph-based clustering, yet current methods like Graph Neural Networks (GNNs), Graph Attention Networks (GATs), and contrastive learning often rely heavily on the original…

Machine Learning · Computer Science 2025-05-21 Jingyun Zhang , Hao Peng , Li Sun , Guanlin Wu , Chunyang Liu , Zhengtao Yu