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In this paper, we aim to address a significant challenge in the field of missing data imputation: identifying and leveraging the interdependencies among features to enhance missing data imputation for tabular data. We introduce a novel…

Machine Learning · Computer Science 2024-11-08 Zhaoyang Zhang , Hongtu Zhu , Ziqi Chen , Yingjie Zhang , Hai Shu

Missing data scenarios are very common in ML applications in general and time-series/sequence applications are no exceptions. This paper pertains to a novel Recurrent Neural Network (RNN) based solution for sequence prediction under missing…

Machine Learning · Computer Science 2022-08-19 Soumen Pachal , Avinash Achar

Treatment effects in a wide range of economic, environmental, and epidemiological applications often vary across space, and understanding the heterogeneity of causal effects across space and outcome quantiles is a critical challenge in…

Methodology · Statistics 2025-09-03 Yan Gong , Reetam Majumder , Brian J. Reich , Raphaël Huser

We present a framework for generating multiple imputations for continuous data when the missing data mechanism is unknown. Imputations are generated from more than one imputation model in order to incorporate uncertainty regarding the…

Applications · Statistics 2013-01-14 Juned Siddique , Ofer Harel , Catherine M. Crespi

This paper studies the inference of the regression coefficient matrix under multivariate response linear regressions in the presence of hidden variables. A novel procedure for constructing confidence intervals of entries of the coefficient…

Methodology · Statistics 2022-01-21 Xin Bing , Wei Cheng , Huijie Feng , Yang Ning

Advances in spatial transcriptomics (ST) technologies enable systematic molecular characterization of tumor microenvironment, tumor gradients and gene regulatory networks. Cancer progression is known to vary along pathological gradients,…

In order to predict and fill in the gaps in categorical datasets, this research looked into the use of machine learning algorithms. The emphasis was on ensemble models constructed using the Error Correction Output Codes framework, including…

Machine Learning · Computer Science 2024-09-13 Muhammad Ishaq , Sana Zahir , Laila Iftikhar , Mohammad Farhad Bulbul , Seungmin Rho , Mi Young Lee

The multivariate linear regression model is an important tool for investigating relationships between several response variables and several predictor variables. The primary interest is in inference about the unknown regression coefficient…

Statistics Theory · Mathematics 2017-09-13 Daniel J. Eck

One limitation of the most statistical/machine learning-based variable selection approaches is their inability to control the false selections. A recently introduced framework, model-x knockoffs, provides that to a wide range of models but…

Machine Learning · Statistics 2025-09-03 Deniz Koyuncu , Alex Gittens , Bülent Yener

We present an approach for imputation of missing items in multivariate categorical data nested within households. The approach relies on a latent class model that (i) allows for household level and individual level variables, (ii) ensures…

Methodology · Statistics 2018-07-05 Olanrewaju Akande , Jerome Reiter , Andrés F. Barrientos

Measurement error in count data is common but underexplored in the literature, particularly in contexts where observed scores are bounded and arise from discrete scoring processes. Motivated by applications in oral reading fluency…

Methodology · Statistics 2025-06-26 Yuqiu Yang , Christina Vu , Cornelis J. Potgieter , Xinlei Wang , Akihito Kamata

Multi-view learning is widely applied to real-life datasets, such as multiple omics biological data, but it often suffers from both missing views and missing labels. Prior probabilistic approaches addressed the missing view problem by using…

Machine Learning · Computer Science 2025-08-18 Yiyang Shen , Weiran Wang

We propose a general nonparametric Bayesian framework for binary regression, which is built from modeling for the joint response-covariate distribution. The observed binary responses are assumed to arise from underlying continuous random…

Methodology · Statistics 2016-09-06 Maria DeYoreo , Athanasios Kottas

Clinical decision support using data mining techniques offers more intelligent way to reduce the decision error in the last few years. However, clinical datasets often suffer from high missingness, which adversely impacts the quality of…

Machine Learning · Computer Science 2020-11-20 Xuetong Wu , Hadi Akbarzadeh Khorshidi , Uwe Aickelin , Zobaida Edib , Michelle Peate

Since survival data occur over time, often important covariates that we wish to consider also change over time. Such covariates are referred as time-dependent covariates. Quantile regression offers flexible modeling of survival data by…

Methodology · Statistics 2014-05-01 Malka Gorfine , Yair Goldberg , Yaacov Ritov

Epigenetic aging clocks play a pivotal role in estimating an individual's biological age through the examination of DNA methylation patterns at numerous CpG (Cytosine-phosphate-Guanine) sites within their genome. However, making valid…

Machine Learning · Statistics 2026-01-21 Zhe Fei , Yi Li

Irregularly sampled multivariate time series (ISMTS) are prevalent in reality. Most existing methods treat ISMTS as synchronized regularly sampled time series with missing values, neglecting that the irregularities are primarily attributed…

Machine Learning · Computer Science 2024-12-03 Jiexi Liu , Meng Cao , Songcan Chen

Missing data are inevitable in longitudinal studies. Traditional methods, such as the full information maximum likelihood (FIML), are commonly used to handle ignorable missing data. However, they may lead to biased model estimation due to…

Applications · Statistics 2024-01-01 Dandan Tang , Xin Tong

Cell-free DNA (cfDNA) analysis is a powerful, minimally invasive tool for monitoring disease progression, treatment response, and early detection. A major challenge, however, is accurately determining the tissue of origin, especially in…

Genomics · Quantitative Biology 2025-06-03 Keng-Jung Lee , Dharanya Sampath , Konstantinos Mavrommatis

Standard (network) meta-analysis methods for medical test accuracy evaluation analyse the data separately for each test threshold - wasting data - unless every study reports all thresholds. Previously proposed "multiple threshold" models…