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The adoption of Digital Twin technologies is rapidly expanding in diverse industrial, economic, and societal domains. Over the past decade, a multitude of studies, surveys, and investigations have been conducted, examining the nature,…

Software Engineering · Computer Science 2026-03-09 Philipp Zech , Yanis Mair , Michael Vierhauser , Pablo Oliveira Antonino , Frank Schnicke , Tony Clark

A patient's digital twin is a computational model that describes the evolution of their health over time. Digital twins have the potential to revolutionize medicine by enabling individual-level computer simulations of human health, which…

Digital Twins (DTs) are computational models that simulate the states and temporal dynamics of real-world systems, playing a crucial role in prediction, understanding, and decision-making across diverse domains. However, existing approaches…

Machine Learning · Computer Science 2024-11-01 Samuel Holt , Tennison Liu , Mihaela van der Schaar

Leveraging hypergraph structures to model advanced processes has gained much attention over the last few years in many areas, ranging from protein-interaction in computational biology to image retrieval using machine learning. Hypergraph…

Human-Computer Interaction · Computer Science 2021-12-07 Maximilian T. Fischer , Alexander Frings , Daniel A. Keim , Daniel Seebacher

Digital twin (DT) technologies have emerged as a solution for real-time data-driven modeling of cyber physical systems (CPS) using the vast amount of data available by Internet of Things (IoT) networks. In this position paper, we elucidate…

Networking and Internet Architecture · Computer Science 2022-04-12 Jithin Jagannath , Keyvan Ramezanpour , Anu Jagannath

Currently, most of the research in digital twins focuses on simulation and optimization. Digital twins are especially useful for critical systems. However, digital twins can also be used for safety and cyber security. The idea of this paper…

Cryptography and Security · Computer Science 2022-05-02 Tianyu Zhao , Ernest Foo , Hui Tian

Over the past decade, scientific machine learning has transformed the development of mathematical and computational frameworks for analyzing, modeling, and predicting complex systems. From inverse problems to numerical PDEs, dynamical…

Machine Learning · Computer Science 2025-09-26 Matthias Chung , Deepanshu Verma , Max Collins , Amit N. Subrahmanya , Varuni Katti Sastry , Vishwas Rao

We demonstrate that graph-based models are fully capable of representing higher-order interactions, and have a long history of being used for precisely this purpose. This stands in contrast to a common claim in the recent literature on…

Physics and Society · Physics 2026-02-20 Tiago P. Peixoto , Leto Peel , Thilo Gross , Manlio De Domenico

Digital Twin (DT) technologies promise to remove cyber-physical barriers in systems and services and provide seamless management of distributed resources effectively. Ideally, full-fledged instantiations of DT offer bi-directional features…

Computational Engineering, Finance, and Science · Computer Science 2024-10-14 Ricardo M. Czekster , Alexeis Garcia Perez , Manolya Kavakli-Thorne , Seif Allah El Mesloul Nasri , Siraj Shaikh

Digital Twin (DT) has gained great interest as an innovative technology in Industry 4.0 that enables advanced modeling, simulation, and optimization of service and manufacturing systems. This article provides an extensive review of the…

General Mathematics · Mathematics 2026-01-26 Sarow Saeedi

In many industries, the scale and complexity of systems can present significant barriers to the development of accurate digital twin models. This paper introduces a novel methodology and a modular computational tool utilizing machine…

Computational Engineering, Finance, and Science · Computer Science 2025-09-23 Deniz Karanfil , Bahram Ravani

The ability to train ever-larger neural networks brings artificial intelligence to the forefront of scientific and technical discoveries. However, their exponentially increasing size creates a proportionally greater demand for energy and…

Digital Twins (DTs) are a conventional and well-known concept, proposed in 70s, that are popular in a broad spectrum of sciences, industry innovations, and consortium alliances. However, in the last few years, the growth of digital assets…

Networking and Internet Architecture · Computer Science 2022-04-26 Saeed Banaeian Far , Azadeh Imani Rad

The mathematical formalisms used to model biological systems induce both latent and ambiguous assumptions that can limit or distort their representational capabilities. Developing formalisms that can represent systems more precisely is…

Quantitative Methods · Quantitative Biology 2026-05-25 Léo Diaz , Sean T. Vittadello , Michael P. H. Stumpf

Background. Digital Twins (DTs) are dynamic virtual representations of physical systems, enabled by seamless, bidirectional communication between the physical and digital realms. Among the challenges impeding the widespread adoption of DTs…

Software Engineering · Computer Science 2025-10-14 Alessandra Somma , Domenico Amalfitano , Alessandra De Benedictis , Patrizio Pelliccione

The acknowledged model for networks of collaborations is the hypergraph model. Nonetheless when it comes to be visualized hypergraphs are transformed into simple graphs. Very often, the transformation is made by clique expansion of the…

Social and Information Networks · Computer Science 2017-07-04 Xavier Ouvrard , Jean-Marie Le Goff , Stéphane Marchand-Maillet

The Metaverse comprises technologies to enable virtual twins of the real world, via mixed reality, internet of things, and others. As it matures unique challenges arise such as a lack of strong connections between virtual and physical…

Human-Computer Interaction · Computer Science 2023-06-05 Jie Guan , Alexis Morris , Jay Irizawa

While network science has become an indispensable tool for studying complex systems, the conventional use of pairwise links often shows limitations in describing high-order interactions properly. Hypergraphs, where each edge can connect…

Physics and Society · Physics 2024-12-20 Zhao Li , Jing Zhang , Jiqiang Zhang , Guozhong Zheng , Weiran Cai , Li Chen

The potential of digital twin technology is yet to be fully realized due to its diversity and untapped potential. Digital twins enable systems' analysis, design, optimization, and evolution to be performed digitally or in conjunction with a…

Cryptography and Security · Computer Science 2024-07-23 MohammadHossein Homaei , Oscar Mogollon Gutierrez , Jose Carlos Sancho Nunez , Mar Avila Vegas , Andres Caro Lindo

The convergence of digital twin technology and quantum computing is opening new horizons for the modeling, control, and optimization of smart grid systems. This paper reviews the current research landscape at the intersection of these…

Quantum Physics · Physics 2025-08-27 Arianne Ornella Lemo , Ahmad Mohammad Saber , Deepa Kundur , Adam W. Skorek
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