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Topological data analysis (TDA) has emerged as one of the most promising techniques to reconstruct the unknown shapes of high-dimensional spaces from observed data samples. TDA, thus, yields key shape descriptors in the form of persistent…

Machine Learning · Statistics 2017-11-15 Wei Guo , Krithika Manohar , Steven L. Brunton , Ashis G. Banerjee

Topological Data Analysis (TDA) has been praised by researchers for its ability to capture intricate shapes and structures within data. TDA is considered robust in handling noisy and high-dimensional datasets, and its interpretability is…

Machine Learning · Computer Science 2024-01-10 Funmilola Mary Taiwo , Umar Islambekov , Cuneyt Gurcan Akcora

Topological features based on persistent homology capture high-order structural information so as to augment graph neural network methods. However, computing extended persistent homology summaries remains slow for large and dense graphs and…

Machine Learning · Computer Science 2022-11-16 Zuoyu Yan , Tengfei Ma , Liangcai Gao , Zhi Tang , Yusu Wang , Chao Chen

Persistent homology, a method from topological data analysis, extracts robust, multi-scale features from data. It produces stable representations of time series by applying varying thresholds to their values (a process known as a…

Computation and Language · Computer Science 2026-04-24 Marius Huber , David R. Reich , Lena A. Jäger

Graph-based learning excels at capturing interaction patterns in diverse domains like recommendation, fraud detection, and particle physics. However, its performance often degrades under distribution shifts, especially those altering…

Machine Learning · Computer Science 2026-05-12 Hans Hao-Hsun Hsu , Shikun Liu , Han Zhao , Pan Li

This paper describes a localized algorithm for the topological simplification of scalar data, an essential pre-processing step of topological data analysis (TDA). Given a scalar field f and a selection of extrema to preserve, the proposed…

Data Structures and Algorithms · Computer Science 2020-09-02 Jonas Lukasczyk , Christoph Garth , Ross Maciejewski , Julien Tierny

In this work, we introduce a filtration on temporal graphs based on $\delta$-temporal motifs (recurrent subgraphs), yielding a multi-scale representation of temporal structure. Our temporal filtration allows tools developed for filtered…

Machine Learning · Computer Science 2025-12-04 Samrik Chowdhury , Siddharth Pritam , Rohit Roy , Madhav Cherupilil Sajeev

Over the years, Principal Component Analysis (PCA) has served as the baseline approach for dimensionality reduction in gene expression data analysis. It primary objective is to identify a subset of disease-causing genes from a vast pool of…

Algebraic Topology · Mathematics 2023-06-13 Sean Cottrell , Rui Wang , Guowei Wei

Persistent homology computes topological invariants from point cloud data. Recent work has focused on developing statistical methods for data analysis in this framework. We show that, in certain models, parametric inference can be performed…

Quantitative Methods · Quantitative Biology 2014-06-19 Kevin Emmett , Daniel Rosenbloom , Pablo Camara , Raul Rabadan

Recent advances in cellular research demonstrate that scRNA-seq characterizes cellular heterogeneity, while spatial transcriptomics reveals the spatial distribution of gene expression. Cell representation is the fundamental issue in the two…

Genomics · Quantitative Biology 2025-01-16 Kai Zheng , Shaokai Wang , Yunpei Xu , Qiming Lei , Qichang Zhao , Xiao Liang , Qilong Feng , Yaohang Li , Min Li , Jinhui Xu , Jianxin Wang

Topological Data Analysis (TDA) is a field that leverages tools and ideas from algebraic topology to provide robust methods for analysing geometric and topological aspects of data. One of the principal tools of TDA, persistent homology,…

High Energy Physics - Lattice · Physics 2023-02-16 Nicholas Sale , Biagio Lucini , Jeffrey Giansiracusa

In this paper, we introduce the persistence transformation, a novel methodology in Topological Data Analysis (TDA) for applications in time series data which can be obtained in various areas such as science, politics, economy, healthcare,…

Algebraic Topology · Mathematics 2024-01-31 Gideon Klaila , Anastasios Stefanou , Lena Ranke

Exploring the shape of point configurations has been a key driver in the evolution of TDA (short for topological data analysis) since its infancy. This survey illustrates the recent efforts to broaden these ideas to model spatial…

Computational Geometry · Computer Science 2024-06-07 Sebastiano Cultrera di Montesano , Ondrej Draganov , Herbert Edelsbrunner , Morteza Saghafian

Tubular structure segmentation (TSS) is important for various applications, such as hemodynamic analysis and route navigation. Despite significant progress in TSS, domain shifts remain a major challenge, leading to performance degradation…

Computer Vision and Pattern Recognition · Computer Science 2025-08-04 Jiale Zhou , Wenhan Wang , Shikun Li , Xiaolei Qu , Xin Guo , Yizhong Liu , Wenzhong Tang , Xun Lin , Yefeng Zheng

This paper introduces new methodology based on the field of Topological Data Analysis for detecting anomalies in multivariate time series, that aims to detect global changes in the dependency structure between channels. The proposed…

Statistics Theory · Mathematics 2024-06-11 Frédéric Chazal , Martin Royer , Clément Levrard

This thesis consists of two topics related to computational geometry and one topic related to topological data analysis (TDA), which combines fields of computational geometry and algebraic topology for analyzing data. The first part studies…

Computational Geometry · Computer Science 2023-01-04 Yury Elkin

Rapid advances in high-throughput technologies have led to considerable interest in analyzing genome-scale data in the context of biological pathways, with the goal of identifying functional systems that are involved in a given phenotype.…

Quantitative Methods · Quantitative Biology 2015-06-01 Rosemary Braun , Sahil Shah

We provide a short introduction to the field of topological data analysis and discuss its possible relevance for the study of complex systems. Topological data analysis provides a set of tools to characterise the shape of data, in terms of…

Data Analysis, Statistics and Probability · Physics 2018-12-05 Vsevolod Salnikov , Daniele Cassese , Renaud Lambiotte

Persistent homology is a common technique in topological data analysis providing geometrical and topological information about the sample space. All this information, known as topological features, is summarized in persistence diagrams, and…

Methodology · Statistics 2022-04-05 Asael Fabian Martínez

The development of machine learning models based on computed tomography (CT) imaging has been a major focus due to the promise that imaging holds for diagnosis, staging, and prognostication. These models often rely on the extraction of…