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Understanding how the brain represents and processes information is crucial for advancing neuroscience and artificial intelligence. Representational similarity analysis (RSA) has been instrumental in characterizing neural representations,…

Neurons and Cognition · Quantitative Biology 2024-08-23 Baihan Lin

Scientific data has been growing in both size and complexity across the modern physical, engineering, life and social sciences. Spatial structure, for example, is a hallmark of many of the most important real-world complex systems, but its…

Persistent homology, a powerful mathematical tool for data analysis, summarizes the shape of data through tracking topological features across changes in different scales. Classical algorithms for persistent homology are often constrained…

Quantum Physics · Physics 2024-02-28 Bernardo Ameneyro , George Siopsis , Vasileios Maroulas

Understanding how the spatial structure of blood vessel networks relates to their function in healthy and abnormal biological tissues could improve diagnosis and treatment for diseases such as cancer. New imaging techniques can generate…

Quantitative Methods · Quantitative Biology 2019-07-23 Helen M Byrne , Heather A Harrington , Ruth Muschel , Gesine Reinert , Bernadette J Stolz , Ulrike Tillmann

Recently, there has been an explosion in statistical learning literature to represent data using topological principles to capture structure and relationships. We propose a topological data analysis (TDA)-based framework, named Topological…

Machine Learning · Statistics 2025-11-10 Jordan Eckert , Elvan Ceyhan , Henry Schenck

Combinatorial and topological structures, such as graphs, simplicial complexes, and cell complexes, form the foundation of geometric and topological deep learning (GDL and TDL) architectures. These models aggregate signals over such…

Machine Learning · Computer Science 2026-05-28 Chuan-Shen Hu

We use Topological Data Analysis tools for studying the inner organization of cells in segmented images of epithelial tissues. More specifically, for each segmented image, we compute different persistence barcodes, which codify lifetime of…

Computer Vision and Pattern Recognition · Computer Science 2022-04-11 N. Atienza , M. J. Jimenez , M. Soriano-Trigueros

This research addresses a new tool for data analysis known as Topological Data Analysis TDA It underlies an area of Mathematics known as Combinatorial Algebra or more recently Algebraic Topology which through making strong use of…

Statistics Theory · Mathematics 2021-06-29 Daniel Trejo Medina , Karla Sarai Jimenez

We present an investigation of the applicability of topological data analysis (TDA) to the study of high-resolution confocal microscopy images of fibrin network structures from patients with oesophageal cancer undergoing intended curative…

Other Quantitative Biology · Quantitative Biology 2026-05-22 Thomas Burnett , Theresa Reinhold , Bea Bleile , Sophie Raynor , Freya Jensen , Martin Hermann , Tua Gyldenholm , Yossi Bokor Bleile

We use the persistent homology method of topological data analysis and dimensional analysis techniques to study data of syntactic structures of world languages. We analyze relations between syntactic parameters in terms of dimensionality,…

Computation and Language · Computer Science 2019-03-14 Alexander Port , Taelin Karidi , Matilde Marcolli

Topological data analysis (TDA) studies the shape patterns of data. Persistent homology is a widely used method in TDA that summarizes homological features of data at multiple scales and stores them in persistence diagrams (PDs). In this…

Machine Learning · Statistics 2022-09-16 Theodore Papamarkou , Farzana Nasrin , Austin Lawson , Na Gong , Orlando Rios , Vasileios Maroulas

A primary hypothesis that drives scientific and engineering studies is that data has structure. The dominant paradigms for describing such structure are statistics (e.g., moments, correlation functions) and signal processing (e.g.,…

Algebraic Topology · Mathematics 2020-11-11 Alexander D. Smith , Pawel Dlotko , Victor M. Zavala

The application of network techniques to the analysis of neural data has greatly improved our ability to quantify and describe these rich interacting systems. Among many important contributions, networks have proven useful in identifying…

Quantitative Methods · Quantitative Biology 2018-06-14 Ann E. Sizemore , Jennifer Phillips-Cremins , Robert Ghrist , Danielle S. Bassett

Improvements in experimental and computational technologies have led to significant increases in data available for analysis. Topological data analysis (TDA) is an emerging area of mathematical research that can identify structures in these…

Quantitative Methods · Quantitative Biology 2022-07-25 Maria-Veronica Ciocanel , Riley Juenemann , Adriana T. Dawes , Scott A. McKinley

Surface roughness plays an important role in analyzing engineering surfaces. It quantifies the surface topography and can be used to determine whether the resulting surface finish is acceptable or not. Nevertheless, while several existing…

Signal Processing · Electrical Eng. & Systems 2021-10-20 Melih C. Yesilli , Firas A. Khasawneh

This work introduces a number of algebraic topology approaches, such as multicomponent persistent homology, multi-level persistent homology and electrostatic persistence for the representation, characterization, and description of small…

Quantitative Methods · Quantitative Biology 2018-02-07 Zixuan Cang , Lin Mu , Guowei Wei

Computational topology provides a tool, persistent homology, to extract quantitative descriptors from structured objects (images, graphs, point clouds, etc). These descriptors can then be involved in optimization problems, typically as a…

Computational Geometry · Computer Science 2026-03-27 Mathieu Carriere , Yuichi Ike , Théo Lacombe , Naoki Nishikawa

In this article, we introduce a Topological Data Analysis (TDA) pipeline for neural spike train data. Understanding how the brain transforms sensory information into perception and behavior requires analyzing coordinated neural population…

Methodology · Statistics 2025-12-10 Cagatay Ayhan , Audrey N. Nash , Roberto Vincis , Martin Bauer , Richard Bertram , Tom Needham

Computational topologists recently developed a method, called persistent homology to analyze data presented in terms of similarity or dissimilarity. Indeed, persistent homology studies the evolution of topological features in terms of a…

Quantitative Methods · Quantitative Biology 2017-08-01 Pavel Petrov , Stephen T Rush , Zhichun Zhai , Christine H Lee , Peter T Kim , Giseon Heo

In topological data analysis (TDA), one often studies the shape of data by constructing a filtered topological space, whose structure is then examined using persistent homology. However, a single filtered space often does not adequately…

Algebraic Topology · Mathematics 2023-03-14 Magnus Bakke Botnan , Michael Lesnick
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