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Sequence data, such as DNA, RNA, and protein sequences, exhibit intricate, multi-scale structures that pose significant challenges for conventional analysis methods, particularly those relying on alignment or purely statistical…

Genomics · Quantitative Biology 2025-10-22 Jian Liu , Li Shen , Mushal Zia , Guo-Wei Wei

We introduce a subsampling method for topological data analysis based on strong collapses of simplicial complexes. Given a point cloud and a scale parameter $\delta$, we construct a subsampling that preserves both global and local…

Computational Geometry · Computer Science 2025-11-27 Elias Gabriel Minian

Persistent topological Laplacians constitute a new class of tools in topological data analysis (TDA). They are motivated by the necessity to address challenges encountered in persistent homology when handling complex data. These Laplacians…

Algebraic Topology · Mathematics 2024-12-12 Xiaoqi Wei , Guo-Wei Wei

Topological Data Analysis (TDA) is a novel statistical technique, particularly powerful for the analysis of large and high dimensional data sets. Much of TDA is based on the tool of persistent homology, represented visually via persistence…

Applications · Statistics 2017-11-07 Sarit Agami , Robert J. Adler

Topological Data Analysis (TDA) gives practioners the ability to analyse the global structure of cybersecurity data. We use TDA for anomaly detection in host-based logs collected with the open-source Logging Made Easy (LME) project. We…

Machine Learning · Computer Science 2022-04-28 Thomas Davies

Topological Data Analysis (TDA) is a rising field of computational topology in which the topological structure of a data set can be observed by persistent homology. By considering a sequence of sublevel sets, one obtains a filtration that…

Methodology · Statistics 2020-03-17 Yu-Min Chung , William Cruse , Austin Lawson

Interacting, self-propelled particles such as epithelial cells can dynamically self-organize into complex multicellular patterns, which are challenging to classify without a priori information. Classically, different phases and phase…

Quantitative Methods · Quantitative Biology 2021-01-19 Dhananjay Bhaskar , William Y. Zhang , Ian Y. Wong

Topological data analysis (TDA) is a rapidly evolving field in applied mathematics and data science that leverages tools from topology to uncover robust, shape-driven insights in complex datasets. The main workhorse is persistent homology,…

History and Overview · Mathematics 2025-07-29 Zhe Su , Xiang Liu , Layal Bou Hamdan , Vasileios Maroulas , Jie Wu , Gunnar Carlsson , Guo-Wei Wei

Topological data analysis (TDA) is a tool from data science and mathematics that is beginning to make waves in environmental science. In this work, we seek to provide an intuitive and understandable introduction to a tool from TDA that is…

Machine Learning · Computer Science 2025-07-15 Lander Ver Hoef , Henry Adams , Emily J. King , Imme Ebert-Uphoff

In this chapter, we discuss applications of topological data analysis (TDA) to spatial systems. We briefly review the recently proposed level-set construction of filtered simplicial complexes, and we then examine persistent homology in two…

Social and Information Networks · Computer Science 2021-04-06 Michelle Feng , Abigail Hickok , Mason A. Porter

In this paper we develop a novel Topological Data Analysis (TDA) approach for studying graph representations of time series of dynamical systems. Specifically, we show how persistent homology, a tool from TDA, can be used to yield a…

Chaotic Dynamics · Physics 2020-01-28 Audun Myers , Elizabeth Munch , Firas A. Khasawneh

This survey provides a comprehensive exploration of applications of Topological Data Analysis (TDA) within neural network analysis. Using TDA tools such as persistent homology and Mapper, we delve into the intricate structures and behaviors…

Machine Learning · Computer Science 2024-01-04 Rubén Ballester , Carles Casacuberta , Sergio Escalera

Topological Data Analysis (TDA) is the collection of mathematical tools that capture the structure of shapes in data. Despite computational topology and computational geometry, the utilization of TDA in time series and signal processing is…

Information Retrieval · Computer Science 2018-10-23 Shafie Gholizadeh , Wlodek Zadrozny

The recent explosion of genomic data has underscored the need for interpretable and comprehensive analyses that can capture complex phylogenetic relationships within and across species. Recombination, reassortment and horizontal gene…

Quantitative Methods · Quantitative Biology 2016-09-28 Pablo G. Camara , Arnold J. Levine , Raul Rabadan

Persistent Homology is a powerful tool in Topological Data Analysis (TDA) to capture topological properties of data succinctly at different spatial resolutions. For graphical data, shape, and structure of the neighborhood of individual data…

Social and Information Networks · Computer Science 2018-11-12 Sumit Bhatia , Bapi Chatterjee , Deepak Nathani , Manohar Kaul

Spatial transcriptomics studies are becoming increasingly large and commonplace, necessitating simultaneous analysis of a large number of spatially resolved variables. Correspondingly, a diverse range of methodologies have been proposed to…

Quantitative Methods · Quantitative Biology 2025-09-09 James Boyle , Gregory Hamm , Eleanor Williams , Robin JG Hartman , Magnus Soderburg , Ian Henry , Michael Casey

Topological Data Analysis (TDA) is an emergent field that aims to discover topological information hidden in a dataset. TDA tools have been commonly used to create filters and topological descriptors to improve Machine Learning (ML)…

Machine Learning · Computer Science 2022-02-07 Rolando Kindelan , José Frías , Mauricio Cerda , Nancy Hitschfeld

Topological data analysis (TDA), while abstract, allows a characterization of time-series data obtained from nonlinear and complex dynamical systems. Though it is surprising that such an abstract measure of structure - counting pieces and…

Computational Geometry · Computer Science 2020-01-07 Nicole Sanderson , Elliott Shugerman , Samantha Molnar , James D. Meiss , Elizabeth Bradley

The absence of a conventional association between the cell-cell cohabitation and its emergent dynamics into cliques during development has hindered our understanding of how cell populations proliferate, differentiate, and compete, i.e. the…

Machine Learning · Computer Science 2022-10-11 Baihan Lin

Topological Data Analysis (TDA) is an emergent field that aims to discover topological information hidden in a dataset. TDA tools have been commonly used to create filters and topological descriptors to improve Machine Learning (ML)…

Machine Learning · Computer Science 2021-02-09 Rolando Kindelan , José Frías , Mauricio Cerda , Nancy Hitschfeld
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