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Lens-free Shadow Imaging Technique (LSIT) is a well-established technique for the characterization of microparticles and biological cells. Due to its simplicity and cost-effectiveness, various low-cost solutions have been evolved, such as…

Image and Video Processing · Electrical Eng. & Systems 2022-03-04 Rajkumar Vaghashiya , Sanghoon Shin , Varun Chauhan , Kaushal Kapadiya , Smit Sanghavi , Sungkyu Seo , Mohendra Roy

Multiplex immunofluorescence (mIF) enables simultaneous single-cell quantification of multiple biomarkers within intact tissue architecture, yet its high reagent cost, multi-round staining protocols, and need for specialized imaging…

Computer Vision and Pattern Recognition · Computer Science 2026-03-18 Junhyeok Lee , Han Jang , Heeseong Eum , Joon Jang , Kyu Sung Choi

We propose a virtual staining methodology based on Generative Adversarial Networks to map histopathology images of breast cancer tissue from H&E stain to PHH3 and vice versa. We use the resulting synthetic images to build Convolutional…

Image and Video Processing · Electrical Eng. & Systems 2020-03-18 Caner Mercan , Germonda Reijnen-Mooij , David Tellez Martin , Johannes Lotz , Nick Weiss , Marcel van Gerven , Francesco Ciompi

How microorganisms respond to and interact with their environment can vary significantly from individual to individual, which can have important microbiological and ecological implications. However, most microscopy techniques can only…

Fluorescence microscopy is essential in biological and medical research, providing critical insights into cellular structures. However, limited by optical diffraction and background noise, a substantial amount of hidden information is still…

Biological Physics · Physics 2026-04-14 Xiaofeng Zhang , Yongsheng Huang , Jielong Yang , Zhili Wang , Si Chen , Linbo Liu , Xin Ge

Histological images are obtained by transmitting light through a tissue specimen that has been stained in order to produce contrast. This process results in 2D images of the specimen that has a three-dimensional structure. In this paper, we…

Computer Vision and Pattern Recognition · Computer Science 2018-01-11 Maxime W. Lafarge , Josien P. W. Pluim , Koen A. J. Eppenhof , Pim Moeskops , Mitko Veta

We introduce a novel approach to single-view face relighting in the wild, addressing challenges such as global illumination and cast shadows. A common scheme in recent methods involves intrinsically decomposing an input image into 3D shape,…

Computer Vision and Pattern Recognition · Computer Science 2026-05-13 Puntawat Ponglertnapakorn , Nontawat Tritrong , Supasorn Suwajanakorn

Portrait harmonization aims to composite a subject into a new background, adjusting its lighting and color to ensure harmony with the background scene. Existing harmonization techniques often only focus on adjusting the global color and…

Computer Vision and Pattern Recognition · Computer Science 2024-04-09 Mengwei Ren , Wei Xiong , Jae Shin Yoon , Zhixin Shu , Jianming Zhang , HyunJoon Jung , Guido Gerig , He Zhang

Optical imaging through scattering media is an important challenge in a variety of fields ranging from microscopy to autonomous vehicles. While advanced wavefront shaping techniques have offered significant breakthroughs in the past decade,…

Optics · Physics 2023-05-23 Omri Haim , Jeremy Boger-Lombard , Ori Katz

We present a deep learning driven computational approach to overcome the limitations of self-interference digital holography that imposed by inferior axial imaging performances. We demonstrate a 3D deep neural network model can…

Previous image based relighting methods require capturing multiple images to acquire high frequency lighting effect under different lighting conditions, which needs nontrivial effort and may be unrealistic in certain practical use…

Computer Vision and Pattern Recognition · Computer Science 2020-08-13 Di Qiu , Jin Zeng , Zhanghan Ke , Wenxiu Sun , Chengxi Yang

Contrastive learning and self-supervised techniques have gained prevalence in computer vision for the past few years. It is essential for medical image analysis, which is often notorious for its lack of annotations. Most existing…

Image and Video Processing · Electrical Eng. & Systems 2022-03-07 Jun Li , Quan Quan , S. Kevin Zhou

Although the advances of self-supervised blind denoising are significantly superior to conventional approaches without clean supervision in synthetic noise scenarios, it shows poor quality in real-world images due to spatially correlated…

Computer Vision and Pattern Recognition · Computer Science 2023-02-22 Kanggeun Lee , Kyungryun Lee , Won-Ki Jeong

Multimodal large language models (MLLMs) have markedly expanded the competence of graphical user-interface (GUI) systems, propelling them beyond controlled simulations into complex, real-world environments across diverse platforms. However,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Bin Lei , Nuo Xu , Ali Payani , Mingyi Hong , Chunhua Liao , Yu Cao , Caiwen Ding

This study details an artificial intelligence (AI)-based methodology for the semantic segmentation of space camera faults. Specifically, we address the segmentation of straylight effects induced by solar presence around the camera's Field…

Computer Vision and Pattern Recognition · Computer Science 2026-02-25 Riccardo Gallon , Fabian Schiemenz , Alessandra Menicucci , Eberhard Gill

Accurate single cell detection in brightfield microscopy is crucial for biological research, yet data scarcity and annotation bottlenecks limit the progress of deep learning methods. We investigate the use of unconditional models to…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Mario de Jesus da Graca , Jörg Dahlkemper , Peer Stelldinger

Active illumination is a prominent complement to enhance 2D face recognition and make it more robust, e.g., to spoofing attacks and low-light conditions. In the present work we show that it is possible to adopt active illumination to…

Computer Vision and Pattern Recognition · Computer Science 2020-04-08 J. Matias Di Martino , Fernando Suzacq , Mauricio Delbracio , Qiang Qiu , Guillermo Sapiro

Tracking cells in 3D at high speed continues to attract extensive attention for many biomedical applications, such as monitoring immune cell migration and observing tumor metastasis in flowing blood vessels. Here, we propose a deep…

Optics · Physics 2018-05-16 Kan Liu , Hui Qiao , Jiamin Wu , Haoqian Wang , Lu Fang , Qionghai Dai

Focus stacking is widely used in micro, macro, and landscape photography to reconstruct all-in-focus images from multiple frames obtained with focus bracketing, that is, with shallow depth of field and different focus planes. Existing deep…

Computer Vision and Pattern Recognition · Computer Science 2023-11-30 Alexandre Araujo , Jean Ponce , Julien Mairal

Gram staining has been one of the most frequently used staining protocols in microbiology for over a century, utilized across various fields, including diagnostics, food safety, and environmental monitoring. Its manual procedures make it…

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