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In the paper, we develop an ensemble-based implicit sampling method for Bayesian inverse problems. For Bayesian inference, the iterative ensemble smoother (IES) and implicit sampling are integrated to obtain importance ensemble samples,…

Numerical Analysis · Mathematics 2018-12-04 Yuming Ba , Lijian Jiang

Importance sampling (IS) is commonly used for cross validation (CV) in Bayesian models, because it only involves reweighting existing posterior draws without needing to re-estimate the model by re-running Markov chain Monte Carlo (MCMC).…

Computation · Statistics 2025-08-12 Geonhee Han , Andrew Gelman

The ability to engineer optimized protein variants has transformative potential for biotechnology and medicine. Prior sequence-based optimization methods struggle with the high-dimensional complexities due to the epistasis effect and the…

Artificial Intelligence · Computer Science 2026-01-19 Jiahao Wang , Shuangjia Zheng

Bayesian experimental design (BED) is a framework that uses statistical models and decision making under uncertainty to optimise the cost and performance of a scientific experiment. Sequential BED, as opposed to static BED, considers the…

Machine Learning · Statistics 2020-03-23 Steven Kleinegesse , Christopher Drovandi , Michael U. Gutmann

In real-world Bayesian inference applications, prior assumptions regarding the parameters of interest may be unrepresentative of their actual values for a given dataset. In particular, if the likelihood is concentrated far out in the wings…

Computation · Statistics 2018-11-01 Xi Chen , Mike Hobson , Saptarshi Das , Paul Gelderblom

This work presents a tractable approach to multi-object posterior computation under a generic measurement likelihood function. While filtering is a popular solution, valuable historical information is discarded. Posterior inference, which…

Computation · Statistics 2026-04-15 Ba Tuong Vo , Ba-Ngu Vo

Two-phase sampling designs have been widely adopted in epidemiological studies to reduce costs when measuring certain biomarkers is prohibitively expensive. Under these designs, investigators commonly relate survival outcomes to risk…

Methodology · Statistics 2025-12-12 Jooho Kim , Yei Eun Shin

The likelihood-informed subspace (LIS) method offers a viable route to reducing the dimensionality of high-dimensional probability distributions arising in Bayesian inference. LIS identifies an intrinsic low-dimensional linear subspace…

Computation · Statistics 2021-10-22 Tiangang Cui , Xin T. Tong

We give a risk-averse solution to the problem of estimating the reliability of a parallel-series system. We adopt a beta-binomial model for components reliabilities, and assume that the total sample size for the experience is fixed. The…

Applications · Statistics 2016-11-15 Zohra Benkamra , Mekki Terbeche , Mounir Tlemcani

In this paper we introduce Refractor Importance Sampling (RIS), an improvement to reduce error variance in Bayesian network importance sampling propagation under evidential reasoning. We prove the existence of a collection of importance…

Artificial Intelligence · Computer Science 2012-06-18 Haohai Yu , Robert A. van Engelen

Deterministic compartmental models are predominantly used in the modeling of infectious diseases, though stochastic models are considered more realistic, yet are complicated to estimate due to missing data. In this paper we present a novel…

Computation · Statistics 2022-06-22 Shuying Wang , Stephen G. Walker

Precision achieved by stochastic sampling algorithms for Bayesian networks typically deteriorates in face of extremely unlikely evidence. To address this problem, we propose the Evidence Pre-propagation Importance Sampling algorithm…

Artificial Intelligence · Computer Science 2012-12-12 Changhe Yuan , Marek J. Druzdzel

Bayesian model selection provides a powerful framework for objectively comparing models directly from observed data, without reference to ground truth data. However, Bayesian model selection requires the computation of the marginal…

Methodology · Statistics 2024-01-17 Xiaohao Cai , Jason D. McEwen , Marcelo Pereyra

Implementing Bayesian inference is often computationally challenging in applications involving complex models, and sometimes calculating the likelihood itself is difficult. Synthetic likelihood is one approach for carrying out inference…

Computation · Statistics 2021-03-15 David T. Frazier , David J. Nott , Christopher Drovandi , Robert Kohn

Parameter inference is a fundamental problem in data-driven modeling. Given observed data that is believed to be a realization of some parameterized model, the aim is to find parameter values that are able to explain the observed data. In…

Data Structures and Algorithms · Computer Science 2016-04-20 Carlo Albert , Simone Ulzega , Ruedi Stoop

Many Bayesian inference problems involve high dimensional models for which only a subset of the model variables are of actual interest. All other variables are just nuisance parameters that one would ideally like to integrate out…

Computation · Statistics 2025-08-13 Fabián González , Víctor Elvira , Joaquín Miguez

Recent advances in Markov chain Monte Carlo (MCMC) extend the scope of Bayesian inference to models for which the likelihood function is intractable. Although these developments allow us to estimate model parameters, other basic problems…

Computation · Statistics 2019-12-12 Minh-Ngoc Tran , Marcel Scharth , David Gunawan , Robert Kohn , Scott D. Brown , Guy E. Hawkins

Probabilistic software analysis aims at quantifying the probability of a target event occurring during the execution of a program processing uncertain incoming data or written itself using probabilistic programming constructs. Recent…

Machine Learning · Computer Science 2021-06-21 Yicheng Luo , Antonio Filieri , Yuan Zhou

We introduce a deep learning image segmentation framework that is extremely robust to missing imaging modalities. Instead of attempting to impute or synthesize missing data, the proposed approach learns, for each modality, an embedding of…

Computer Vision and Pattern Recognition · Computer Science 2016-07-19 Mohammad Havaei , Nicolas Guizard , Nicolas Chapados , Yoshua Bengio

Estimation of small failure probabilities is one of the most important and challenging computational problems in reliability engineering. The failure probability is usually given by an integral over a high-dimensional uncertain parameter…

Computation · Statistics 2011-10-18 Konstantin M. Zuev , James L. Beck , Siu-Kui Au , Lambros S. Katafygiotis
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