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Large Language Models (LLMs) are known to hallucinate, whereby they generate plausible but inaccurate text. This phenomenon poses significant risks in critical applications, such as medicine or law, necessitating robust hallucination…

Computation and Language · Computer Science 2024-10-23 Benedict Aaron Tjandra , Muhammed Razzak , Jannik Kossen , Kunal Handa , Yarin Gal

In this study, we propose a structured methodology that utilizes large language models (LLMs) in a cost-efficient and parsimonious manner, integrating the strengths of scholars and machines while offsetting their respective weaknesses. Our…

Computation and Language · Computer Science 2025-12-30 Navid Asgari , Benjamin M. Cole

The modeling of bio-molecular system across molecular scales remains a central challenge in scientific research. Large language models (LLMs) are increasingly applied to bio-molecular discovery, yet systematic evaluation across multi-scale…

Machine Learning · Computer Science 2026-04-07 Yaxin Xu , Yue Zhou , Tianyu Zhao , Fengwei An , Zhixiang Ren

Autonomous vehicle navigation in complex environments such as dense and fast-moving highways and merging scenarios remains an active area of research. A key limitation of RL is its reliance on well-specified reward functions, which often…

Machine Learning · Computer Science 2025-11-18 Timur Anvar , Jeffrey Chen , Yuyan Wang , Rohan Chandra

The demand for efficient large language model (LLM) inference has propelled the development of dedicated accelerators. As accelerators are vulnerable to hardware faults due to aging, variation, etc, existing accelerator designs often…

Hardware Architecture · Computer Science 2025-04-08 Tong Xie , Jiawang Zhao , Zishen Wan , Zuodong Zhang , Yuan Wang , Runsheng Wang , Ru Huang , Meng Li

Molecular discovery, when formulated as an optimization problem, presents significant computational challenges because optimization objectives can be non-differentiable. Evolutionary Algorithms (EAs), often used to optimize black-box…

Models such as GPT-4 and Med-PaLM 2 have demonstrated impressive performance on a wide variety of biomedical NLP tasks. However, these models have hundreds of billions of parameters, are computationally expensive to run, require users to…

Large Language Models (LLMs) represent a landmark achievement in Artificial Intelligence (AI), demonstrating unprecedented proficiency in procedural tasks such as text generation, code completion, and conversational coherence. These…

Artificial Intelligence · Computer Science 2025-05-07 Schaun Wheeler , Olivier Jeunen

The advancement in generative AI could be boosted with more accessible mathematics. Beyond human-AI chat, large language models (LLMs) are emerging in programming, algorithm discovery, and theorem proving, yet their genomics application is…

Other Quantitative Biology · Quantitative Biology 2023-07-07 Melanie Swan , Takashi Kido , Eric Roland , Renato P. dos Santos

Large Language Models (LLMs) enable a new form of digital experimentation where treatments combine human and model-generated content in increasingly sophisticated ways. The main methodological challenge in this setting is representing these…

Methodology · Statistics 2025-10-27 Lei Shi , David Arbour , Raghavendra Addanki , Ritwik Sinha , Avi Feller

While large language models (LLMs) demonstrate impressive capabilities across numerous applications, their robustness remains a critical concern. This paper is motivated by a specific vulnerability: the order sensitivity of LLMs. This…

Machine Learning · Computer Science 2025-05-22 Beni Egressy , Jan Stühmer

Large language models (LLMs) often suffer from catastrophic forgetting in continual learning: after learning new tasks sequentially, they perform worse on earlier tasks. Existing methods mitigate catastrophic forgetting by data replay,…

Machine Learning · Computer Science 2026-05-08 Yazheng Liu , Yuxuan Wan , Rui Xu , Xi Zhang , Sihong Xie , Hui Xiong

Automating the enrichment of UML class diagrams with behavioral methods from natural language use cases is a significant challenge. This study evaluates nine large language models (LLMs) in augmenting a methodless UML diagram (21 classes,…

Software Engineering · Computer Science 2025-06-03 Djaber Rouabhia , Ismail Hadjadj

The sequential recommendation problem has attracted considerable research attention in the past few years, leading to the rise of numerous recommendation models. In this work, we explore how Large Language Models (LLMs), which are nowadays…

Information Retrieval · Computer Science 2025-01-14 Artun Boz , Wouter Zorgdrager , Zoe Kotti , Jesse Harte , Panos Louridas , Dietmar Jannach , Vassilios Karakoidas , Marios Fragkoulis

While Large Language Models (LLMs) have exhibited remarkable emergent capabilities through extensive pre-training, they still face critical limitations in generalizing to specialized domains and handling diverse linguistic variations, known…

Computation and Language · Computer Science 2025-05-28 Jinwu Hu , Zhitian Zhang , Guohao Chen , Xutao Wen , Chao Shuai , Wei Luo , Bin Xiao , Yuanqing Li , Mingkui Tan

We propose a novel approach to enhancing the performance and efficiency of large language models (LLMs) by combining domain prompt routing with domain-specialized models. We introduce a system that utilizes a BERT-based router to direct…

Computation and Language · Computer Science 2024-10-11 Toby Simonds , Kemal Kurniawan , Jey Han Lau

Retrieval-augmented generation (RAG) has emerged as an approach to augment large language models (LLMs) by reducing their reliance on static knowledge and improving answer factuality. RAG retrieves relevant context snippets and generates an…

Computation and Language · Computer Science 2025-02-21 Juraj Vladika , Florian Matthes

Generative AI, particularly Large Language Models, increasingly integrates graph-based representations to enhance reasoning, retrieval, and structured decision-making. Despite rapid advances, there remains limited clarity regarding when,…

Artificial Intelligence · Computer Science 2026-04-21 Hamed Jelodar , Samita Bai , Mohammad Meymani , Parisa Hamedi , Roozbeh Razavi-Far , Ali Ghorbani

This paper introduces a system that integrates large language models (LLMs) into the clinical trial retrieval process, enhancing the effectiveness of matching patients with eligible trials while maintaining information privacy and allowing…

Information Retrieval · Computer Science 2024-11-01 Georgios Peikos , Pranav Kasela , Gabriella Pasi

As healthcare increasingly turns to AI for scalable and trustworthy clinical decision support, ensuring reliability in model reasoning remains a critical challenge. Individual large language models (LLMs) are susceptible to hallucinations…

Machine Learning · Computer Science 2025-12-05 Huascar Sanchez , Briland Hitaj , Jules Bergmann , Linda Briesemeister