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We introduce MetaChem, a language for representing and implementing Artificial Chemistries. We motivate the need for modularisation and standardisation in representation of artificial chemistries. We describe a mathematical formalism for…

Emerging Technologies · Computer Science 2020-06-16 Penelope Faulkner Rainford , Angelika Sebald , Susan Stepney

Recently, there has been increasing interest in using Large Language Models (LLMs) to construct complex multi-agent systems to perform tasks such as compiling literature reviews, drafting consumer reports, and planning vacations. Many tools…

Computation and Language · Computer Science 2024-11-06 Andrew Zhu , Liam Dugan , Chris Callison-Burch

Machine learning (ML) has demonstrated the promise for accurate and efficient property prediction of molecules and crystalline materials. To develop highly accurate ML models for chemical structure property prediction, datasets with…

This paper presents RDCSim, an interactive simulator for reaction--diffusion chemistry (RDC) research, being developed as part of an ongoing project studying how humans interact with unconventional computing systems. While much research…

Emerging Technologies · Computer Science 2019-01-23 James Stovold

RESPACK is a first-principles calculation software for evaluating the interaction parameters of materials and is able to calculate maximally localized Wannier functions, response functions based on the random phase approximation and related…

Applications in science and engineering often require huge computational resources for solving problems within a reasonable time frame. Parallel supercomputers provide the computational infrastructure for solving such problems. A…

Distributed, Parallel, and Cluster Computing · Computer Science 2007-05-23 Rajesh Sudarsan , Calvin J. Ribbens

Machine learning (ML) is increasingly becoming a common tool in computational chemistry. At the same time, the rapid development of ML methods requires a flexible software framework for designing custom workflows. MLatom 3 is a program…

We treat the accurate simulation of the calcination reaction in particles, where the particles are large and, thus, the inner-particle processes must be resolved. Because these processes need to be described with coupled partial…

Fluid Dynamics · Physics 2023-11-28 Lucas Reineking , Torben Bergold , Enric Illana , Viktor Scherer , Martin Mönnigmann

In this paper, we present ChemRecon, a meta-database and Python interface for integrating and exploring biochemical data across multiple heterogeneous resources by consolidating compounds, reactions, enzymes, molecular structures, and…

Quantitative Methods · Quantitative Biology 2026-02-16 Casper Asbjørn Eriksen , Jakob Lykke Andersen , Rolf Fagerberg , Daniel Merkle

Runko is a new open-source plasma simulation framework implemented in C++ and Python. It is designed to function as an easy-to-extend general toolbox for simulating astrophysical plasmas with different theoretical and numerical models.…

Computational Physics · Physics 2022-08-10 J. Nättilä

A novel extension of a rapid compression machine (RCM), namely a Rapid Compression Expansion Machine (RCEM), is described and its use for studying chemical kinetics is demonstrated. Like conventional RCMs, the RCEM quickly compresses a…

Chemical Physics · Physics 2016-06-21 Marc Werler , Robert Schiessl , Ulrich Maas

Identifying reliable synthesis pathways in materials chemistry is a complex task, particularly in polymer science, due to the intricate and often non-unique nomenclature of macromolecules. To address this challenge, we propose an agent…

Artificial Intelligence · Computer Science 2025-04-16 Qinyu Ma , Yuhao Zhou , Jianfeng Li

Organic synthesis stands as a cornerstone of the chemical industry. The development of robust machine learning models to support tasks associated with organic reactions is of significant interest. However, current methods rely on…

Machine Learning · Computer Science 2025-01-06 Kaipeng Zeng , Xianbin Liu , Yu Zhang , Xiaokang Yang , Yaohui Jin , Yanyan Xu

We propose a novel computational strategy for de novo design of molecules with desired properties termed ReLeaSE (Reinforcement Learning for Structural Evolution). Based on deep and reinforcement learning approaches, ReLeaSE integrates two…

Artificial Intelligence · Computer Science 2018-07-30 Mariya Popova , Olexandr Isayev , Alexander Tropsha

Graph rewrite systems are powerful tools to model and study complex problems in various fields of research. Their successful application to chemical reaction modelling on a molecular level was shown but no appropriate and simple system is…

Mathematical Software · Computer Science 2013-04-05 Martin Mann , Heinz Ekker , Christoph Flamm

Prediction of complete step-by-step chemical reaction mechanisms (CRMs) remains a major challenge. Whereas the traditional approaches in CRM tasks rely on expert-driven experiments or costly quantum chemical computations, contemporary deep…

Chemical Physics · Physics 2025-12-11 Manajit Das , Ajnabiul Hoque , Mayank Baranwal , Raghavan B. Sunoj

ML4Chem is an open-source machine learning library for chemistry and materials science. It provides an extendable platform to develop and deploy machine learning models and pipelines and is targeted to the non-expert and expert users.…

Chemical Physics · Physics 2020-03-31 Muammar El Khatib , Wibe A de Jong

Artificial intelligence (AI) has demonstrated significant promise in advancing organic chemistry research; however, its effectiveness depends on the availability of high-quality chemical reaction data. Currently, most published chemical…

Computer Vision and Pattern Recognition · Computer Science 2025-03-12 Yufan Chen , Ching Ting Leung , Jianwei Sun , Yong Huang , Linyan Li , Hao Chen , Hanyu Gao

In this paper, we present a study on how to develop an efficient multiscale simulation strategy for the dynamics of chemically active systems on low-dimensional supports. Such reactions are encountered in a wide variety of situations,…

Computational Physics · Physics 2015-06-04 Giacomo Mazzi , Yannick De Decker , Giovanni Samaey

CHEMSMART (Chemistry Simulation and Modeling Automation Toolkit) is an open-source, Python-based framework designed to streamline quantum chemistry workflows for homogeneous catalysis and molecular modeling. By integrating job preparation,…

Chemical Physics · Physics 2025-08-28 Xinglong Zhang , Huiwen Tan , Jingyi Liu , Zihan Li , Lewen Wang , Benjamin W. J. Chen