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This article reviews the evolving field of radiobiology, emphasizing the need for advanced multiscale, mechanistic models to optimize radiopharmaceutical therapies (RPT). While the traditional linear-quadratic (LQ) model underpins external…

Medical Physics · Physics 2025-09-23 Tahir Yusufaly , Hamid Abdollahi , Babak Saboury , Arman Rahmim

We establish an equivalence between two classes of methods for solving fractional diffusion problems, namely, Reduced Basis Methods (RBM) and Rational Krylov Methods (RKM). In particular, we demonstrate that several recently proposed RBMs…

Numerical Analysis · Mathematics 2021-03-01 Tobias Danczul , Clemens Hofreither

Kinetic transport equations are notoriously difficult to simulate because of their complex multiscale behaviors and the need to numerically resolve a high dimensional probability density function. Past literature has focused on building…

Numerical Analysis · Mathematics 2022-11-10 Zhichao Peng , Yanlai Chen , Yingda Cheng , Fengyan Li

Segregated Runge-Kutta (SRK) schemes are time integration methods for the incompressible Navier-Stokes equations. In this approach, convection and diffusion can be independently treated either explicitly or implicitly, which in particular…

Numerical Analysis · Mathematics 2025-06-12 Pavel Bakhvalov

In this paper, we develop a new type of Runge--Kutta (RK) discontinuous Galerkin (DG) method for solving hyperbolic conservation laws. Compared with the original RKDG method, the new method features improved compactness and allows simple…

Numerical Analysis · Mathematics 2024-02-26 Qifan Chen , Zheng Sun , Yulong Xing

We study global optimization (GOP) in the framework of non-linear inverse problems with a unique solution. These problems are in general ill-posed. Evaluation of the objective function is often expensive, as it implies the solution of a…

Numerical Analysis · Mathematics 2007-05-23 W. Jacquet , B. Truyen , P. de Groen , I. Lemahieu , J. Cornelis

This paper introduces the Runge-Kutta Chebyshev descent method (RKCD) for strongly convex optimisation problems. This new algorithm is based on explicit stabilised integrators for stiff differential equations, a powerful class of numerical…

Optimization and Control · Mathematics 2020-06-30 Armin Eftekhari , Bart Vandereycken , Gilles Vilmart , Konstantinos C. Zygalakis

Perturbed Runge--Kutta methods (also referred to as downwind Runge--Kutta methods) can guarantee monotonicity preservation under larger step sizes relative to their traditional Runge--Kutta counterparts. In this paper we study, the question…

Numerical Analysis · Mathematics 2018-02-16 Inmaculada Higueras , David I. Ketcheson , Tihamér A. Kocsis

To overcome these obstacles and improve computational accuracy and efficiency, this paper presents the Randomized Radial Basis Function Neural Network (RRNN), an innovative approach explicitly crafted for solving multiscale elliptic…

Numerical Analysis · Mathematics 2024-07-23 Yuhang Wu , Ziyuan Liu , Wenjun Sun , Xu Qian

The aim of this paper is to show how rapidly decaying RBF Lagrange functions on the spheres can be used to create effective, stable finite difference methods based on radial basis functions (RBF-FD). For certain classes of PDEs this…

Numerical Analysis · Mathematics 2023-02-17 Wolfgang Erb , Thomas Hangelbroek , Francis J. Narcowich , Christian Rieger , Joseph D. Ward

This article aims to develop a direct numerical approach to solve the space-fractional partial differential equations (PDEs) based on a new differential quadrature (DQ) technique. The fractional derivatives are approximated by the weighted…

Numerical Analysis · Mathematics 2017-01-24 X. G. Zhu , Y. F. Nie

We propose a quantum algorithm based on ridge regression model, which get the optimal fitting parameters w and a regularization hyperparameter {\alpha} by analysing the training dataset. The algorithm consists of two subalgorithms. One is…

Quantum Physics · Physics 2021-04-28 Menghan Chen , Chaohua Yu , Gongde Guo , Song Lin

Optimal control methods provide solutions to safety-critical problems but easily become intractable. Control Barrier Functions (CBFs) have emerged as a popular technique that facilitates their solution by provably guaranteeing safety,…

Systems and Control · Electrical Eng. & Systems 2025-02-21 Ehsan Sabouni , H. M. Sabbir Ahmad , Vittorio Giammarino , Christos G. Cassandras , Ioannis Ch. Paschalidis , Wenchao Li

One of main obstacles in verifying the energy dissipation laws of implicit-explicit Runge-Kutta (IERK) methods for phase field equations is to establish the uniform boundedness of stage solutions without the global Lipschitz continuity…

Numerical Analysis · Mathematics 2024-12-11 Hong-lin Liao , Tao Tang , Xuping Wang , Tao Zhou

The radial basis function (RBF) approach is applied in predicting nuclear masses for 8 widely used nuclear mass models, ranging from macroscopic-microscopic to microscopic types. A significantly improved accuracy in computing nuclear masses…

Nuclear Theory · Physics 2013-09-03 Z. M. Niu , Z. L. Zhu , Y. F. Niu , B. H. Sun , T. H. Heng , J. Y. Guo

In this paper, we present a method based on Radial Basis Function (RBF)-generated Finite Differences (FD) for numerically solving diffusion and reaction-diffusion equations (PDEs) on closed surfaces embedded in $\mathbb{R}^d$. Our method…

Numerical Analysis · Mathematics 2014-04-04 Varun Shankar , Grady B. Wright , Robert M. Kirby , Aaron L. Fogelson

In this research a novel stochastic gradient descent based learning approach for the radial basis function neural networks (RBFNN) is proposed. The proposed method is based on the q-gradient which is also known as Jackson derivative. In…

This paper introduces a novel framework for the solution of (large-scale) Lyapunov and Sylvester equations derived from numerical integration methods. Suitable systems of ordinary differential equations are introduced. Low-rank…

Numerical Analysis · Mathematics 2021-04-13 Christian Bertram , Heike Faßbender

In this paper, two new families of fourth-order explicit exponential Runge--Kutta (ERK) methods with four stages are studied for solving first-order differential systems $y'(t)+My(t)=f(y(t))$. By comparing the Taylor series of the exact…

Numerical Analysis · Mathematics 2024-06-19 Xianfa Hu , Yonglei Fang , Bin Wang

We describe the optimization algorithm implemented in the open-source derivative-free solver RBFOpt. The algorithm is based on the radial basis function method of Gutmann and the metric stochastic response surface method of Regis and…

Machine Learning · Computer Science 2021-02-02 Giacomo Nannicini