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Simulating many-body fermionic systems in conventional qubit-based quantum computers poses significant challenges due to the overheads associated with the encoding of fermionic statistics in qubits, leading to the proposal of native…

Quantum Physics · Physics 2025-12-15 Ahana Ghoshal , Carlos de Gois , Kiara Hansenne , Otfried Gühne , Hai-Chau Nguyen

The procedure for simulating the nuclear magnetic resonance spectrum linked to the spin system of a molecule for a certain nucleus entails diagonalizing the associated Hamiltonian matrix. As the dimensions of said matrix grow exponentially…

Quantum Physics · Physics 2024-10-29 Joaquín Ossorio-Castillo , Alexandre Rodríguez-Coello

Quantum computing has shown great potential in various quantum chemical applications such as drug discovery, material design, and catalyst optimization. Although significant progress has been made in quantum simulation of simple molecules,…

Quantum Physics · Physics 2023-05-30 Changsu Cao , Jinzhao Sun , Xiao Yuan , Han-Shi Hu , Hung Q. Pham , Dingshun Lv

Compiling quantum circuits to account for hardware restrictions is an essential part of the quantum computing stack. Circuit compilation allows us to adapt algorithm descriptions into a sequence of operations supported by real quantum…

Quantum Physics · Physics 2025-10-14 Alejandro Villoria , Henning Basold , Alfons Laarman

We demonstrate the feasibility of quantum computing for large-scale, realistic chemical systems through the development of a new interface using a quantum circuit simulator and CP2K, a highly efficient first-principles calculation software.…

Chemical Physics · Physics 2025-06-24 Tomoya Shiota , Klaas Gunst , Toshio Mori , Toru Shiozaki , Wataru Mizukami

Quantum simulations of molecular systems on quantum computers often employ minimal basis sets of Gaussian orbitals. In comparison with more realistic basis sets, quantum simulations employing minimal basis sets require fewer qubits and…

Quantum Physics · Physics 2022-08-17 Stefano Barison , Davide Emilio Galli , Mario Motta

Quantum chemistry simulations on a quantum computer suffer from the overhead needed for encoding the fermionic problem in a bosonic system of qubits. By exploiting the block diagonality of a fermionic Hamiltonian, we show that the number of…

Quantum Physics · Physics 2016-06-09 Nikolaj Moll , Andreas Fuhrer , Peter Staar , Ivano Tavernelli

Recent demonstrations of superconducting quantum computers by Google and IBM and trapped-ion computers from IonQ fueled new research in quantum algorithms, compilation into quantum circuits, and empirical algorithmics. While online access…

Quantum Physics · Physics 2020-11-26 Aneeqa Fatima , Igor L. Markov

Currently available quantum computing hardware platforms have limited 2-qubit connectivity among their addressable qubits. In order to run a generic quantum algorithm on such a platform, one has to transform the initial logical quantum…

Quantum Physics · Physics 2020-04-28 Beatrice Nash , Vlad Gheorghiu , Michele Mosca

Quantum computers have the potential to simulate chemical systems beyond the capability of classical computers. Recent developments in hybrid quantum-classical approaches enable the determinations of the ground or low energy states of…

Quantum Physics · Physics 2021-12-06 Chee-Kong Lee , Jonathan Wei Zhong Lau , Liang Shi , Leong Chuan Kwek

Quantum algorithms for simulating large and complex molecular systems are still in their infancy, and surpassing state-of-the-art classical techniques remains an ever-receding goal post. A promising avenue of inquiry in the meanwhile is to…

Quantum Physics · Physics 2025-08-07 Soohaeng Yoo Willow , D. ChangMo Yang , Chang Woo Myung

First quantized, grid-based methods for chemistry modelling are a natural and elegant fit for quantum computers. However, it is infeasible to use today's quantum prototypes to explore the power of this approach, because it requires a…

Quantum Physics · Physics 2023-03-09 Hans Hon Sang Chan , Richard Meister , Tyson Jones , David P. Tew , Simon C. Benjamin

Simulating the time evolution of a physical system at quantum mechanical levels of detail -- known as Hamiltonian Simulation (HS) -- is an important and interesting problem across physics and chemistry. For this task, algorithms that run on…

Optimal control theory is a powerful tool for solving control problems in quantum mechanics, ranging from the control of chemical reactions to the implementation of gates in a quantum computer. Gradient-based optimization methods are able…

Quantum Physics · Physics 2015-10-06 Michael H. Goerz , K. Birgitta Whaley , Christiane P. Koch

We provide a simple framework for the synthesis of quantum circuits based on a numerical optimization algorithm. This algorithm is used in the context of the trapped-ions technology. We derive theoretical lower bounds for the number of…

Emerging Technologies · Computer Science 2020-04-17 Timothée Goubault de Brugière , Marc Baboulin , Benoît Valiron , Cyril Allouche

Quantum computers do not run in isolation; rather, they are embedded in quantum-classical hybrid architectures. In these setups, a quantum processing unit communicates with a classical device in near-real time. To enable efficient hybrid…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-05-20 Lian Remme , Alexander Weinert , Andre Waschk

We conduct a systematic study of quantum circuits composed of multiple-control $Z$-rotation (MCZR) gates as primitives, since they are widely-used components in quantum algorithms and also have attracted much experimental interest in recent…

Quantum Physics · Physics 2024-06-11 Shihao Zhang , Junda Wu , Lvzhou Li

Quantum simulation, the simulation of quantum processes on quantum computers, suggests a path forward for the efficient simulation of problems in condensed-matter physics, quantum chemistry, and materials science. While the majority of…

Quantum Physics · Physics 2022-10-03 Paul K. Faehrmann , Mark Steudtner , Richard Kueng , Maria Kieferova , Jens Eisert

Gradient-based optimization is a key ingredient of variational quantum algorithms, with applications ranging from quantum machine learning to quantum chemistry and simulation. The parameter-shift rule provides a hardware-friendly method for…

Quantum Physics · Physics 2025-10-08 Leonardo Banchi , Dominic Branford , Chetan Waghela

In leading fault-tolerant quantum computing schemes, accurate transformation are obtained by a two-stage process. In a first stage, a discrete, universal set of fault-tolerant operations is obtained by error-correcting noisy transformations…

Quantum Physics · Physics 2015-04-22 Guillaume Duclos-Cianci , David Poulin
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