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In this work, we propose Oph-Guid-RAG, a multimodal visual RAG system for ophthalmology clinical question answering and decision support. We treat each guideline page as an independent evidence unit and directly retrieve page images,…

Artificial Intelligence · Computer Science 2026-03-24 Shuying Chen , Sen Cui , Zhong Cao

This work presents a Biomedical Literature Question Answering (Q&A) system based on a Retrieval-Augmented Generation (RAG) architecture, designed to improve access to accurate, evidence-based medical information. Addressing the shortcomings…

Computation and Language · Computer Science 2025-09-09 Mansi Garg , Lee-Chi Wang , Bhavesh Ghanchi , Sanjana Dumpala , Shreyash Kakde , Yen Chih Chen

As AI chatbots gain adoption in clinical medicine, developing effective frameworks for complex, emerging diseases presents significant challenges. We developed and evaluated six Retrieval-Augmented Generation (RAG) corpus configurations for…

Artificial Intelligence · Computer Science 2025-10-20 Philip DiGiacomo , Haoyang Wang , Jinrui Fang , Yan Leng , W Michael Brode , Ying Ding

Clients wishing to implement generative AI in the domain of IT Support and AIOps face two critical issues: domain coverage and model size constraints due to model choice limitations. Clients might choose to not use larger proprietary models…

This paper presents the development and evaluation of a Retrieval-Augmented Generation (RAG) system for querying the United Kingdom's National Institute for Health and Care Excellence (NICE) clinical guidelines using Large Language Models…

Automated question-answering (QA) systems increasingly rely on retrieval-augmented generation (RAG) to ground large language models (LLMs) in authoritative medical knowledge, ensuring clinical accuracy and patient safety in Artificial…

Computation and Language · Computer Science 2026-03-05 Aswini Sivakumar , Vijayan Sugumaran , Yao Qiang

Vaccination plays a vital role in global public health, yet healthcare professionals often struggle to access immunization guidelines quickly and efficiently. National protocols and WHO recommendations are typically extensive and complex,…

Computation and Language · Computer Science 2025-07-08 Abdellah Zeggai , Ilyes Traikia , Abdelhak Lakehal , Abdennour Boulesnane

Cancer treatments require personalized approaches based on a patient's clinical condition, medical history, and evidence-based guidelines. The National Comprehensive Cancer Network (NCCN) provides frequently updated, complex guidelines…

Information Retrieval · Computer Science 2025-02-25 Abdul M. Mohammed , Iqtidar Mansoor , Sarah Blythe , Dennis Trujillo

Retrieval-augmented generation (RAG) is a popular technique for using large language models (LLMs) to build customer-support, question-answering solutions. In this paper, we share our team's practical experience building and maintaining…

Information Retrieval · Computer Science 2024-10-18 Sarah Packowski , Inge Halilovic , Jenifer Schlotfeldt , Trish Smith

The rapid growth of medical knowledge and increasing complexity of clinical practice pose challenges. In this context, large language models (LLMs) have demonstrated value; however, inherent limitations remain. Retrieval-augmented…

Retrieval-augmented generation (RAG) mitigates hallucination in Large Language Models (LLMs) by using query pipelines to retrieve relevant external information and grounding responses in retrieved knowledge. However, query pipeline…

Computation and Language · Computer Science 2026-04-17 Maolin He , Rena Gao , Mike Conway , Brian E. Chapman

Biomedical question-answering (QA) systems require effective retrieval and generation components to ensure accuracy, efficiency, and scalability. This study systematically examines a Retrieval-Augmented Generation (RAG) system for…

Information Retrieval · Computer Science 2026-01-14 Linus Stuhlmann , Michael Alexander Saxer , Jonathan Fürst

Virtual health counselors offer the potential to provide users with information and counseling in complex areas such as disease management and health education. However, ensuring user engagement is challenging, particularly when the volume…

Human-Computer Interaction · Computer Science 2024-07-09 Mina Fallah , Farnaz Nouraei , Hye Sun Yun , Timothy Bickmore

Despite the success of integrating large language models into the development of conversational systems, many studies have shown the effectiveness of retrieving and augmenting external knowledge for informative responses. Hence, many…

Computation and Language · Computer Science 2024-08-01 Xi Wang , Procheta Sen , Ruizhe Li , Emine Yilmaz

Accurate and efficient access to laboratory protocols is essential in Anatomical Pathology (AP), where up to 70% of medical decisions depend on laboratory diagnoses. However, static documentation such as printed manuals or PDFs is often…

Information Retrieval · Computer Science 2026-02-27 Diogo Pires , Yuriy Perezhohin , Mauro Castelli

We propose Retrieval Augmented Generation (RAG) as an approach for automated radiology report writing that leverages multimodally aligned embeddings from a contrastively pretrained vision language model for retrieval of relevant candidate…

Computation and Language · Computer Science 2023-05-08 Mercy Ranjit , Gopinath Ganapathy , Ranjit Manuel , Tanuja Ganu

Recently, Large Language Models (LLMs) have been increasingly used to support various decision-making tasks, assisting humans in making informed decisions. However, when LLMs confidently provide incorrect information, it can lead humans to…

Information Retrieval · Computer Science 2025-10-16 Chaeyun Jang , Deukhwan Cho , Seanie Lee , Hyungi Lee , Juho Lee

Safe and trustworthy use of Large Language Models (LLM) in the processing of healthcare documents and scientific papers could substantially help clinicians, scientists and policymakers in overcoming information overload and focusing on the…

Large language models (LLMs) often generate outdated or inaccurate information based on static training datasets. Retrieval-augmented generation (RAG) mitigates this by integrating outside data sources. While previous RAG systems used…

Retrieval-Augmented Generation (RAG) has emerged as a critical technique for enhancing large language model (LLM) capabilities. However, practitioners face significant challenges when making RAG deployment decisions. While existing research…

Software Engineering · Computer Science 2025-07-22 Shengming Zhao , Yuchen Shao , Yuheng Huang , Jiayang Song , Zhijie Wang , Chengcheng Wan , Lei Ma
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