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Molecular odor prediction has great potential across diverse fields such as chemistry, pharmaceuticals, and environmental science, enabling the rapid design of new materials and enhancing environmental monitoring. However, current methods…

Machine Learning · Computer Science 2025-02-04 HongXin Xie , JianDe Sun , Yi Shao , Shuai Li , Sujuan Hou , YuLong Sun , Yuxiang Liu

Neuromorphic computing is one of the few current approaches that have the potential to significantly reduce power consumption in Machine Learning and Artificial Intelligence. Imam & Cleland presented an odour-learning algorithm that runs on…

Neural and Evolutionary Computing · Computer Science 2023-09-22 Nik Dennler , André van Schaik , Michael Schmuker

Despite extraordinary progress in artificial intelligence (AI), modern systems remain incomplete representations of human cognition. Vision, audition, and language have received disproportionate attention due to well-defined benchmarks,…

Artificial Intelligence · Computer Science 2025-06-03 Kordel K. France , Rohith Peddi , Nik Dennler , Ovidiu Daescu

We explore a suite of generative modelling techniques to efficiently navigate and explore the complex landscapes of odor and the broader chemical space. Unlike traditional approaches, we not only generate molecules but also predict the odor…

Machine Learning · Computer Science 2025-02-03 Mrityunjay Sharma , Sarabeshwar Balaji , Pinaki Saha , Ritesh Kumar

Numerous studies have attempted to demonstrate the olfactory ability of canines to detect several common cancer types from human bodily fluids, breath and tissue. Canines have been reported to detect bladder cancer (sensitivity of 0.63-0.73…

Tissues and Organs · Quantitative Biology 2015-10-20 Oliver Gould , Amy Smart , Norman Ratcliffe , Ben de Lacy Costello

This work presents a general chemical reaction network theory for olfactory sensing processes that employ G-protein-coupled receptors as olfactory receptors (ORs). The theory is applicable to general mixtures of odorants and an arbitrary…

Molecular Networks · Quantitative Biology 2023-09-06 Won Kyu Kim , Kiri Choi , Changbong Hyeon , Seogjoo J. Jang

The convergent interests of different scientific disciplines, from biochemistry to electronics, toward the investigation of protein electrical properties, has promoted the development of a novel bailiwick, the so called proteotronics. The…

Soft Condensed Matter · Physics 2014-05-16 E. Alfinito , L. Reggiani , J. Pousset

Animal behavior and neural recordings show that the brain is able to measure both the intensity of an odor and the timing of odor encounters. However, whether intensity or timing of odor detections is more informative for olfactory-driven…

Quantitative Methods · Quantitative Biology 2021-06-17 Nicola Rigolli , Nicodemo Magnoli , Lorenzo Rosasco , Agnese Seminara

Ovarian cancer (OC) is one of the most prevalent types of cancer in women. Early and accurate diagnosis is crucial for the survival of the patients. However, the majority of women are diagnosed in advanced stages due to the lack of…

Machine Learning · Computer Science 2024-07-31 Asif Newaz , Abdullah Taharat , Md Sakibul Islam , A. G. M. Fuad Hasan Akanda

Olfactory systems use a small number of broadly sensitive receptors to combinatorially encode a vast number of odors. We propose a method of decoding such distributed representations by exploiting a statistical fact: receptors that do not…

Neurons and Cognition · Quantitative Biology 2021-09-01 Vijay Singh , Martin Tchernookov , Vijay Balasubramanian

The olfactory system is constantly solving pattern-recognition problems by the creation of a large space to codify odour representations and optimizing their distribution within it. A model of the Olfactory Bulb was developed by Z. Li and…

Adaptation and Self-Organizing Systems · Physics 2019-05-16 Alexandra Pinto

The human brain encodes stimuli from the environment into representations that form a sensory perception of the world. Despite recent advances in understanding visual and auditory perception, olfactory perception remains an under-explored…

Machine Learning · Computer Science 2024-11-06 Farzaneh Taleb , Miguel Vasco , Antônio H. Ribeiro , Mårten Björkman , Danica Kragic

Embeddings from contemporary natural language processing (NLP) models are commonly used as numerical representations for words or sentences. However, odor descriptor words, like "leather" or "fruity", vary significantly between their…

Machine Learning · Computer Science 2022-05-10 Laura Sisson

Recordings from neurons in the insects' olfactory primary processing center, the antennal lobe (AL), reveal that the AL is able to process the input from chemical receptors into distinct neural activity patterns, called olfactory neural…

Neurons and Cognition · Quantitative Biology 2014-08-27 Eli Shlizerman , Jeffrey A. Riffell , J. Nathan Kutz

Local computation in microcircuits is an essential feature of distributed information processing in vertebrate and invertebrate brains. The insect antennal lobe represents a spatially confined local network that processes high-dimensional…

Neurons and Cognition · Quantitative Biology 2012-12-27 Anneke Meyer , Giovanni Galizia , Martin P. Nawrot

Molecular communication is a new, active area of research that has created a paradigm shift in the way a communication system is perceived. An artificial molecular communication network is created using biological molecules for encoding,…

Emerging Technologies · Computer Science 2023-12-01 Aditya Powari , Ozgur B. Akan

One of the key challenges to predict odor from molecular structure is unarguably our limited understanding of the odor space and the complexity of the underlying structure-odor relationships. Here, we show that the predictive performance of…

Quantitative Methods · Quantitative Biology 2025-08-14 Akshay Sajan , Stijn Sluis , Reza Haydarlou , Sanne Abeln , Pasquale Lisena , Raphael Troncy , Caro Verbeek , Inger Leemans , Halima Mouhib

A treatment benefit predictor (TBP) is a function that maps patient characteristics to an estimate of the treatment benefit for that patient. Such predictors support optimizing individualized treatment decisions, which are central to…

Methodology · Statistics 2025-09-30 Yuan Xia , Mohsen Sadatsafavi , Paul Gustafson

In this paper we propose the use of the Word2vec algorithm in order to obtain odor perception embeddings (or smell embeddings), only using publicly available perfume descriptions. Besides showing meaningful similarity relationships among…

Computation and Language · Computer Science 2022-03-22 Janek Amann , Manex Agirrezabal

Odor sensory evaluation has a broad application in food, clothing, cosmetics, and other fields. Traditional artificial sensory evaluation has poor repeatability, and the machine olfaction represented by the electronic nose (E-nose) is…

Artificial Intelligence · Computer Science 2023-11-27 Xiuxin Xia , Yuchen Guo , Yanwei Wang , Yuchao Yang , Yan Shi , Hong Men