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Electronic transitions involving core-level orbitals offer a localized, atomic-site and element specific peek window into statistical systems such as molecular liquids. Although formally understood, the complex relation between structure…

Chemical Physics · Physics 2022-09-02 Johannes Niskanen , Anton Vladyka , J. Antti Kettunen , Christoph J. Sahle

We propose a simple, but efficient and accurate machine learning (ML) model for developing high-dimensional potential energy surface. This so-called embedded atom neural network (EANN) approach is inspired by the well-known empirical…

Chemical Physics · Physics 2019-10-23 Yaolong Zhang , Ce Hu , Bin Jiang

Accurately predicting the survival rate of cancer patients is crucial for aiding clinicians in planning appropriate treatment, reducing cancer-related medical expenses, and significantly enhancing patients' quality of life. Multimodal…

Computer Vision and Pattern Recognition · Computer Science 2024-03-15 Liangrui Pan , Yijun Peng , Yan Li , Xiang Wang , Wenjuan Liu , Liwen Xu , Qingchun Liang , Shaoliang Peng

While investigating methods to predict small molecule potencies, we found random forests or support vector machines paired with extended-connectivity fingerprints (ECFP) consistently outperformed recently developed methods. A detailed…

Biomolecules · Quantitative Biology 2023-10-03 James H. Notwell , Michael W. Wood

Soot is an important material with impacts that depend on particle morphology. Transmission electron microscopy (TEM) represents one of the most direct routes to qualitatively assess particle characteristics. However, producing quantitative…

Applied Physics · Physics 2022-02-01 Timothy A. Sipkens , Max Frei , Alberto Baldelli , P. Kirchen , Frank E. Kruis , Steven N. Rogak

In this article, we establish the mathematical foundations for modeling the randomness of shapes and conducting statistical inference on shapes using the smooth Euler characteristic transform. Based on these foundations, we propose two…

Methodology · Statistics 2024-05-27 Kun Meng , Jinyu Wang , Lorin Crawford , Ani Eloyan

In recent years the machine learning techniques have shown a great potential in various problems from a multitude of disciplines, including materials design and drug discovery. The high computational speed on the one hand and the accuracy…

Chemical Physics · Physics 2018-05-09 Konstantin Gubaev , Evgeny V. Podryabinkin , Alexander V. Shapeev

Multimodal molecular representation learning, which jointly models molecular graphs and their textual descriptions, enhances predictive accuracy and interpretability by enabling more robust and reliable predictions of drug toxicity,…

Machine Learning · Computer Science 2025-10-21 Yingxu Wang , Kunyu Zhang , Jiaxin Huang , Nan Yin , Siwei Liu , Eran Segal

Molecular representation learning plays a crucial role in AI-assisted drug discovery research. Encoding 3D molecular structures through Euclidean neural networks has become the prevailing method in the geometric deep learning community.…

Machine Learning · Computer Science 2023-03-29 Yiqun Wang , Yuning Shen , Shi Chen , Lihao Wang , Fei Ye , Hao Zhou

Prediction and discovery of new materials with desired properties are at the forefront of quantum science and technology research. A major bottleneck in this field is the computational resources and time complexity related to finding new…

Multivariate time series classification (MTSC) has attracted significant research attention due to its diverse real-world applications. Recently, exploiting transformers for MTSC has achieved state-of-the-art performance. However, existing…

Machine Learning · Computer Science 2024-05-24 Xuan-May Le , Ling Luo , Uwe Aickelin , Minh-Tuan Tran

The electron density of a molecule or material has recently received major attention as a target quantity of machine-learning models. A natural choice to construct a model that yields transferable and linear-scaling predictions is to…

Chemical Physics · Physics 2022-06-29 Andrea Grisafi , Alan M. Lewis , Mariana Rossi , Michele Ceriotti

Convolutional Neural Networks (CNN) have been successful in processing data signals that are uniformly sampled in the spatial domain (e.g., images). However, most data signals do not natively exist on a grid, and in the process of being…

Computer Vision and Pattern Recognition · Computer Science 2019-01-09 Chiyu "Max" Jiang , Dequan Wang , Jingwei Huang , Philip Marcus , Matthias Nießner

Molecular generative models often assume meaningful latent geometry, but apparent property predictability can reflect sequence-level shortcuts rather than chemical organization. We study this issue in an unsupervised autoregressive…

Machine Learning · Computer Science 2026-05-08 Zakaria Elabid , Jan Andrzejewski , Bartosz Brzoza , Attila Cangi

Tiered graph autoencoders provide the architecture and mechanisms for learning tiered latent representations and latent spaces for molecular graphs that explicitly represent and utilize groups (e.g., functional groups). This enables the…

Machine Learning · Computer Science 2021-07-02 Daniel T. Chang

Obesity is a common issue in modern societies today that can lead to various diseases and significantly reduced quality of life. Currently, research has been conducted to investigate resting state EEG (electroencephalogram) signals with an…

Machine Learning · Computer Science 2023-02-03 Yuan Yue , Jeremiah D. Deng , Dirk De Ridder , Patrick Manning , Divya Adhia

We present a Machine Learning approach to solve electronic quantum transport equations of one-dimensional nanostructures. The transmission coefficients of disordered systems were computed to provide training and test datasets to the…

Mesoscale and Nanoscale Physics · Physics 2015-06-18 Alejandro Lopez-Bezanilla , O. Anatole von Lilienfeld

The Absorption, Distribution, Metabolism, Elimination, and Toxicity (ADMET) properties of drug candidates are estimated to account for up to 50% of all clinical trial failures. Predicting ADMET properties has therefore been of great…

Machine Learning · Computer Science 2019-03-29 Evan N. Feinberg , Robert Sheridan , Elizabeth Joshi , Vijay S. Pande , Alan C. Cheng

The preformation factor quantifies the probability of {\alpha} particles preforming on the surface of the parent nucleus in decay theory and is closely related to the study of {\alpha} clustering structure. In this work, a multilayer…

Nuclear Theory · Physics 2025-04-04 Jiaqi Luo , Yang Xu , Xiaolong Li , Junxiang Wang , Yangjie Zhang , Jungang Deng , Fang Zhang , Nana Ma

Deep learning is an important method for molecular design and exhibits considerable ability to predict molecular properties, including physicochemical, bioactive, and ADME/T (absorption, distribution, metabolism, excretion, and toxicity)…

Molecular Networks · Quantitative Biology 2022-05-10 Hanxuan Cai , Huimin Zhang , Duancheng Zhao , Jingxing Wu , Ling Wang